Results 91 to 100 of about 254,914 (259)

Shell Neurons of the Master Circadian Clock Coordinate the Phase of Tissue Clocks Throughout the Brain and Body [PDF]

, 2015
Background: Daily rhythms in mammals are programmed by a master clock in the suprachiasmatic nucleus (SCN). The SCN contains two main compartments (shell and core), but the role of each region in system-level coordination remains ill defined.
Baba, Kenkichi, Baker, Kimberly M., Bartness, Timothy J., Callif, Ben L., Castanon-Cervantes, Oscar, Davidson, Alec J., Ehlen, J. Christopher, Evans, Jennifer A., Kloehn, Ian, Leise, Tanya, Mitchell, Andrew S., Paul, Ketema N., Suen, Ting-Chung, Teubner, Brett J.W., Tosini, Gianluca   +14 more
core   +2 more sources

White-to-Beige and Back: Adipocyte Conversion and Transcriptional Reprogramming

Pharmaceuticals
Obesity has become a pandemic, as currently more than half a billion people worldwide are obese. The etiology of obesity is multifactorial, and combines a contribution of hereditary and behavioral factors, such as nutritional inadequacy, along with the ...
Stanislav Boychenko, Vera S. Egorova, Andrew Brovin, Alexander D. Egorov   +3 more
doaj   +1 more source

Short photoperiod-induced decrease of histamine H3 receptors facilitates activation of hypothalamic neurons in the Siberian Hamster [PDF]

, 2009
Nonhibernating seasonal mammals have adapted to temporal changes in food availability through behavioral and physiological mechanisms to store food and energy during times of predictable plenty and conserve energy during predicted shortage.
Bamshad, Barrett, Barrett, Brown, C. K. Song, D. Spanswick, D. Wilson, Doi, Enriori, Franklin, Franklin, Garcia, Gottsch, Inagaki, J. G. Mercer, Jamali, Jamali, Leurs, Liu, M. van den Top, Malmlöf, Morgan, Morgan, Morton, Nakamura, Nilaweera, Ookuma, P. Barrett, P. J. Morgan, Panula, Pillot, Prendergast, Revel, Ross, Sakata, Sallmen, Sallmen, Schneider, Song, Spanswick, Spanswick, T. J. Bartness, Top, Tups, Viguié, Yoshimoto, Yoshimura   +46 more
core   +1 more source

PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity. [PDF]

, 2019
(1) Background: Paraoxonase 2 (PON2) is a ubiquitously expressed protein localized to endoplasmic reticulum and mitochondria. Previous studies have shown that PON2 exhibits anti-oxidant and anti-inflammatory functions, and PON2-deficient (PON2-def) mice ...
Fogelman, Alan M, Lusis, Aldons J, Meng, Yonghong, Reddy, Srinivasa T, Reue, Karen, Sallam, Tamer, Shih, Diana M, Shu, Michelle L, Tontonoz, Peter, Vergnes, Laurent   +9 more
core   +1 more source

Inductive Effect and Mechanism of EGCG on Beiging of White Adipose Tissue in High-fat Diet-fed GK Rats [PDF]

Chaye kexue
The types of adipose tissue are closely related to human metabolism. Transforming white adipocytes into thermogenic beige adipocytes through dietary or nutritional interventions is a safe strategy to reduce fat accumulation and regulate metabolism ...
WAN Liwei, ZENG Hongzhe, PENG Liyuan, WEN Shuai, LIU Changwei, BAO Sudu, AN Qin, HUANG Jian'an, LIU Zhonghua
doaj   +1 more source

Adipose extracellular matrix remodelling in obesity and insulin resistance [PDF]

, 2016
The extracellular matrix (ECM) of adipose tissues undergoes constant remodelling to allow adipocytes and their precursor cells to change cell shape and function in adaptation to nutritional cues.
Agnihotri, Aouadi, Arany, Aumailley, Bauters, Berger, Bertola, Bonnans, Bonner, Bourlier, Brahimi-Horn, Brakenhielm, Brew, Cao, Chapman, Chavey, Chinsomboon, Choi, Chun, Chun, Chun, Daviet, De Lin, Derosa, Desgrosellier, Divoux, Facchini, Febbraio, Feral, Filippov, Fraser, Gerin, Ghosh, Hajri, Halberg, Hames, Han, Haslam, Heni, Hopps, Huber, Hynes, Inoue, Jaworski, Ji, Jiang, Kahles, Kandalam, Kang, Kang, Kang, Kang, Khan, Kiefer, Kiefer, Kleiner, Kodama, Kulkarni, Lancha, Lawler, Lee, Leick, Li, Li Kang, Lijnen, Lijnen, Liu, Liu, Lu, Luk, Lumeng, Maquoi, Maquoi, Mariman, Martinez-Santibanez, Matsuo, Meakin, Menghini, Menghini, Miller, Moore, Murphy, Nagase, Naor, Nasser, Nergiz-Unal, Nicholls, Nomiyama, Oh, Ponta, Rong, Rowe, Rupnick, Sato, Signorelli, Spencer, Stern, Strissel, Sun, Sun, Sun, Sun, Sung, Szabova, Tae-Hwa Chun, Takahashi, Thomas, Thrailkill, Tinahones, Tracy, Traurig, Van Hul, Van Hul, Van Hul, Van Hul, Varma, Weis, Wentworth, Williams, Wu, Yang, Yeh, Zheng, Zoller, Zong   +124 more
core   +2 more sources

Perivascular adipose tissue as a relevant fat depot for cardiovascular risk in obesity [PDF]

, 2018
Obesity is associated with increased risk of premature death, morbidity, and mortality from several cardiovascular diseases (CVDs), including stroke, coronary heart disease (CHD), myocardial infarction, and congestive heart failure.
Costa, Rafael M., Lobato, Núbia S., Neves, Karla B., Tostes, Rita C.   +3 more
core   +3 more sources

Development of brown and white adipose tissue

Journal of Lipid Research, 1975
In this review, it is assumed that the reader is familiar with the basic properties of white and brown adipose tissue. The role and metabolic characteristics of both tissues in adult mammals have been adequately and repeatedly reviewed (1-3) and will be mentioned here only insofar as they impinge upon developmental aspects. Macroscopically brown fat is
P. Hahn, M. Novak
openaire   +3 more sources

Cold-induced changes in gene expression in brown adipose tissue, white adipose tissue and liver [PDF]

, 2013
Cold exposure imposes a metabolic challenge to mammals that is met by a coordinated response in different tissues to prevent hypothermia. This study reports a transcriptomic analysis in brown adipose tissue (BAT), white adipose (WAT) and liver of mice in
A Karamitri, A Shore, A Unami, AL Vallerand, Andrew M. Shore, Angeliki Karamitri, AV Gabova, B Cannon, B Cannon, BM Spiegelman, DW Gong, G Karamanlidis, H Ohguchi, J Liu, J Moitra, JE Silva, JK Kim, John R. Speakman, JR Hall, K Kajimoto, M Solter, M Watanabe, M Watanabe, M Watanabe, MA Thorne, Marc Lenburg, ME Symonds, Michael A. Lomax, N Yamazaki, Neil S. Graham, O Gavrilova, O Gavrilova, O Gavrilova, OA Gavrilova, Paul Kemp, PE Penner, R Edgar, S Bi, S Yu, T Daikoku, T Yamamoto, TB Walden   +41 more
core   +5 more sources

Sox9-Meis1 Inactivation Is Required for Adipogenesis, Advancing Pref-1+ to PDGFRα+ Cells. [PDF]

, 2018
Adipocytes arise from the commitment and differentiation of adipose precursors in white adipose tissue (WAT). In studying adipogenesis, precursor markers, including Pref-1 and PDGFRα, are used to isolate precursors from stromal vascular fractions of WAT,
Gulyaeva, Olga, Heydari, Kartoosh, Nguyen, Hai, Sambeat, Audrey, Sul, Hei Sook   +4 more
core   +1 more source