Results 151 to 160 of about 388,905 (379)

Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes

Journal of physiology and biochemistry, 2018
Mammalian adipose tissue is traditionally categorized into white and brown relating to their function and morphology: while white serves as an energy storage, brown adipose tissue acts as the heat generator maintaining the core body temperature. The most
A. Kaisanlahti, Tumo Glumoff
semanticscholar   +1 more source

Tributyltin Enhances Macrophage Inflammation and Lipolysis, Contributing to Adipose Tissue Dysfunction [PDF]

: Tributyltin (TBT) is a synthetic chemical widely used in industrial and commercial applications. TBT exposure has been proven to elicit obesogenic effects.
Blumberg, Bruce, Chang, Richard C, Huang, Yikai, Joloya, Erika, To, Kaitlin Thanh, Whitlock, Ryan Scott   +5 more
core   +1 more source

CD90 is dispensable for white and beige/brown adipocyte differentiation [PDF]

, 2020
Brown adipose tissue (BAT) is a thermogenic organ in rodents and humans. In mice, the transplantation of BAT has been successfully used to combat obesity and its comorbidities.
Dahlhaus, Meike, Debatin, Klaus-Michael, Döscher, Johannes, Engel, Daniel, Fischer-Posovszky, Pamela, Funcke, Jan-Bernd, Halbgebauer, Daniel, Hoffmann, Thomas K., Kiener, Sophie, Rojewski, Markus, Roos, Julian, Schrezenmeier, Hubert, Schuler, Patrick J., Tews, Daniel, Wabitsch, Martin, Zinngrebe, Julia   +15 more
core   +1 more source

Host Plasma Microenvironment in Immunometabolically Impaired HIV Infection Leads to Dysregulated Monocyte Function and Synaptic Transmission Ex Vivo

Advanced Science, EarlyView.
Network‐based risk stratification of people living with HIV (PWH) on prolonged therapy using multi‐omics data identifies 44% of the patients are at risk of immunometabolic complications. A senescence‐associated myeloid cell‐driven plasma microenvironment drives immunometabolic dysregulation in at‐risk PWH.
Flora Mikaeloff, Marco Gelpi, Alejandra Escós, Tianqi Wang, Soham Gupta, Anna Olofsson, Sara Svensson Akusjärvi, Sabrina Schuster, Prajakta Naval, Vikas Sood, Negin Nikouyan, Andreas D. Knudsen, Beate Vestad, Julie Høgh, Johannes R. Hov, Thomas Benfield, Marius Trøseid, Vinay Pawar, Marijana Rucevic, Rui Benfeitas, Ákos Végvári, Liam O'Mahony, Rajkumar Savai, Niklas K. Björkström, Magda Lourda, João Pedro de Magalhães, Siegfried Weiss, Adil Mardinoglu, Mukesh Kumar Varshney, Annika C. Karlsson, Yasir Ahmed Syed, Susanne D. Nielsen, Ujjwal Neogi   +32 more
wiley   +1 more source

The anti‐obesity and anti‐diabetic effects of the edible seaweed Gloiopeltis furcata (Postels et Ruprecht) J. Agardh in mice fed a high‐fat diet

Food Science &Nutrition, Volume 11, Issue 1, Page 599-610, January 2023., 2023
Edible red seaweed G. furcata alleviates obesity and associated metabolic disorders in mice fed a high fat diet by suppressing intestinal lipid absorption, oxidative stress and inflammation. Abstract Obesity and diabetes are serious, chronic medical conditions associated with a wide range of life‐threatening conditions.
Shigeru Murakami, Chihiro Hirazawa, Toshiki Mizutani, Rina Yoshikawa, Takuma Ohya, Ning Ma, Yutaka Owaki, Toyohiro Owaki, Takashi Ito, Chiaki Matsuzaki   +9 more
wiley   +1 more source

White-to-Beige and Back: Adipocyte Conversion and Transcriptional Reprogramming

Pharmaceuticals
Obesity has become a pandemic, as currently more than half a billion people worldwide are obese. The etiology of obesity is multifactorial, and combines a contribution of hereditary and behavioral factors, such as nutritional inadequacy, along with the ...
Stanislav Boychenko, Vera S. Egorova, Andrew Brovin, Alexander D. Egorov   +3 more
doaj   +1 more source

The Circadian Clock in White and Brown Adipose Tissue: Mechanistic, Endocrine, and Clinical Aspects.

Endocrine reviews, 2018
Obesity is a major risk factor for the development of illnesses, such as insulin resistance and hypertension, and has become a serious public health problem. Mammals have developed a circadian clock located in the hypothalamic suprachiasmatic nuclei (SCN)
O. Froy, M. Garaulet
semanticscholar   +1 more source

Acute Rejection of White Adipose Tissue Allograft

Cell Transplantation, 2007
White adipose tissue (WAT) transplantation, although widely used in humans, has been done for cosmetic and reconstructive purposes only. Accumulating evidence indicates, however, that WAT is an important endocrine organ and, therefore, WAT transplantation may become valuable as a replacement therapy for a number of hereditary human diseases.
Simon Klebanov, Simon Klebanov, Alan J. Goldstein, Alan J. Goldstein, Marina H. Tovbina, Marina H. Tovbina, Vitaly Ablamunits, Vitaly Ablamunits, Harold P. Gaetz   +8 more
openaire   +4 more sources

Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species

Advanced Science, EarlyView.
This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu, Xing‐Yue Zhou, Da‐Lian Qin, Qan Qiao, Qiao‐Zhi Wang, Shi‐Ying Li, Yun‐Fei Zhu, Ya‐Ping Li, Jiang‐Min Zhou, Hui Cai, Fei‐Hong Huang, Lu Yu, Long Wang, An‐Guo Wu, Jian‐Ming Wu, Xiao‐Gang Zhou   +15 more
wiley   +1 more source

Exercise-induced adaptations to white and brown adipose tissue

Journal of Experimental Biology, 2018
The beneficial effects of exercise on skeletal muscle and the cardiovascular system have long been known. Recent studies have focused on investigating the effects of exercise on adipose tissue and the effects that these exercise-induced adaptations have ...
Adam C. Lehnig, K. Stanford
semanticscholar   +1 more source