Results 171 to 180 of about 131,653 (265)

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger   +3 more
wiley   +1 more source

Assessing Metabolic and Reproductive Consequences of Prenatal Paracetamol Exposure in Female CD1 Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Paracetamol is a widely used analgesic during pregnancy; however, emerging evidence suggests it may act as an endocrine/metabolism disrupting compound. Using an F1 female CD1 mouse model, this study scrutinized the long‐term metabolic and reproductive consequences linked to intrauterine paracetamol exposure.
Bita Entezari   +7 more
wiley   +1 more source

The microbial metabolite desaminotyrosine is a potent antiobesity agent with potential effects on white adipose tissue remodeling in mice. [PDF]

open access: yesGut Microbes
Huang H   +11 more
europepmc   +1 more source

Heavy Metal Mixture Exposure and Insulin Resistance in U.S. Adults: The Mediating Role of Systemic Inflammation

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
In a nationally representative sample of 3042 U.S. adults from NHANES 2021–2023, blood lead, cadmium, and mercury, both individually and as a weighted quantile sum (WQS) mixture, were inversely associated with insulin resistance assessed by HOMA‐IR. Systemic inflammation, measured by high‐sensitivity C‐reactive protein (hs‐CRP), significantly mediated ...
Cai Zhang, Shidi Lin, Yu Lin
wiley   +1 more source

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

open access: yesJournal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini   +3 more
wiley   +1 more source

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