Results 201 to 210 of about 356,218 (360)

Harnessing nanomaterials to precisely regulate the immunosuppressive tumor microenvironment for enhanced immunotherapy

BMEMat, EarlyView.
The immunosuppressive tumor microenvironment, characterized by hypoxia, redox imbalance, elevated interstitial fluid pressure, and acidity, was comprehensively elucidated. This review discussed the etiology and consequences of the characteristics of the immunosuppressive tumor microenvironment, and analyzed the recent advancements in nanomaterials for ...
Wen Zhang, Xueyin Hu, Wei Cheng, Lumeng Zhang, Yuanfang Chen, Qinrui Fu, Luntao Liu, Saijun Fan   +7 more
wiley   +1 more source

Obesity drives depot-specific vascular remodeling in male white adipose tissue. [PDF]

Nat Commun
Hasan SS, John D, Rudnicki M, AlZaim I, Eberhard D, Moll I, Taylor J, Klein C, von Heesen M, Conradi LC, Adams RH, Lammert E, Kalucka J, Ruhrberg C, Dimmeler S, Fischer A.   +15 more
europepmc   +1 more source

Obesity, White Adipose Tissue, and Adipokines Signaling in Male Reproduction. [PDF]

Mol Nutr Food Res
Martins FF, Amarante MDSM, Oliveira DS, Vasques-Monteiro IML, Souza-Mello V, Daleprane JB, Camillo CDS.   +6 more
europepmc   +1 more source

Angiotensin II as a Trophic Factor of White Adipose Tissue: Stimulation of Adipose Cell Formation**This work was supported by a grant from the Fondation pour la Recherche Médicale.

, 2001
Perla Saint-Marc, Leslie P. Kozak, Gérard Ailhaud, Christian Darimont, Raymond Négrel   +4 more
openalex   +1 more source

Insulin regulation of gene expression and concentrations of white adipose tissue-derived proteins in vivo in healthy men: relation to adiponutrin [PDF]

, 2006
May Faraj, Geneviève Beauregard, Emmanuelle Loizon, Marthe Moldes, Karine Clément, Youssef Tahiri, Katherine Cianflone, Hubert Vidal, Rémi Rabasa-Lhoret   +8 more
openalex   +1 more source

Associations of body mass index and waist circumference with incidence of overall and of 27 site‐specific cancers: a population‐based retrospective cohort study

Cancer Communications, EarlyView.
Abstract Background Overweight and obesity are known risk factors for cancer. The aim of this study was to investigate associations of body mass index (BMI) and waist circumference (WC) with incidence of 27 site‐specific cancers stratified by sex and menopausal status accounting for non‐linearity.
Seonghye Kim, Bongseong Kim, Kyu‐won Jung, Ga Eun Nam, Wonyoung Jung, Junhee Park, Kyung‐Do Han, Dong Wook Shin   +7 more
wiley   +1 more source

Antiaging, Wound‐Healing Properties and Chemical Characterization of Crude Hydroalcoholic Extract and Fractions of Myrcia neoobscura

Chemistry &Biodiversity, EarlyView.
ABSTRACT The aim of this study was to characterize the phytochemical profile and potential antiaging and wound‐healing activities of 70% hydroalcoholic crude extract (CHE) from Myrcia neoobscura leaves and its fractions—insoluble (IF), ethyl acetate (EAF), and aqueous (AF)—for use in phytocosmetics for skin application.
Larissa Mascarenhas Krepsky, Ana Helena Loos Moritz, Mayra Alice Corrêa Pitz, Letícia Bachmann, Diogo Alexandre Siebert, Paula Flegar, Stjepan Lešnjak, Ana Tirić, Amanda Tavares Germano, Mayara da Silva, Carlos Rafael Vaz, Larissa Benvenutti, André Luís de Gasper, José Roberto Santin, Isabel Daufenback Machado, Luciano Vitali, Marijana Zovko Končić, Michele Debiasi Alberton   +17 more
wiley   +1 more source

Sulfonylureas exert antidiabetic action on adipocytes by inhibition of PPARγ serine 273 phosphorylation

Molecular Metabolism
Objective: Sulfonylureas (SUs) are still among the mostly prescribed antidiabetic drugs with an established mode of action: release of insulin from pancreatic β-cells.
Bodo Haas, Moritz David Sebastian Hass, Alexander Voltz, Matthias Vogel, Julia Walther, Arijit Biswas, Daniela Hass, Alexander Pfeifer   +7 more
doaj  

Consumption of resistant starch decreases postprandial lipogenesis in white adipose tissue of the rat [PDF]

, 2006
Janine Higgins, Marc A. Brown, Leonard H Storlien   +2 more
openalex   +1 more source

Synthesis of New N,N′‐Diarylureas and Their Theoretical Study as Cannabinoid‐1 Receptor Inhibitors

ChemPlusChem, EarlyView.
A series of new pyrazolo‐ and triazolo‐based N,N′‐diarylureas is synthesized following the triphosgene protocol in the last step. Density functional theory calculations and molecular docking provide strong evidence that all new compounds bind strongly to the cannabinoid‐1 (CB‐1) receptor, showing comparable results with the known allosteric CB‐1 ...
Eirini Tsemperlidou, Nikitas Georgiou, Demeter Tzeli, Nikolaos Karousis, George Varvounis   +4 more
wiley   +1 more source