Results 41 to 50 of about 388,905 (379)

Brown vs white adipocytes: The PPARγ coregulator story [PDF]

open access: yes, 2010
The development of adipose tissue is a process which involves the concerted cooperation of numerous transcription factors together with their coactivators and corepressors.
Kalkhoven, Eric, Koppen, Arjen
core   +1 more source

De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis

open access: yesNature Communications, 2018
Long non-coding RNAs are known to regulate mouse white adipose tissue development and brown adipose tissue program expression. Here, the authors construct a roadmap for human long non-coding RNAs expressed in fetal brown adipose tissue, adult omental and
Chunming Ding   +12 more
doaj   +1 more source

Expression profiles and gene set enrichment analysis of the transcriptomes from the cancer tissue, white adipose tissue and paracancer tissue with colorectal cancer [PDF]

open access: yesPeerJ
Background Colorectal cancer (CRC) is one of the most common cancers worldwide and is related to diet and obesity. Currently, crosstalk between lipid metabolism and CRC has been reported; however, the specific mechanism is not yet understood.
Xiufeng Zhang   +9 more
doaj   +2 more sources

Epigenetic regulation of white adipose tissue plasticity and energy metabolism by nucleosome binding HMGN proteins

open access: yesNature Communications, 2022
White adipose tissue browning plays an important role in regulating whole-body energy homeostasis and metabolism. Here the authors show that the HMGN nucleosome binding proteins epigenetically promote white adipocyte differentiation and modulate the rate
Ravikanth Nanduri   +9 more
doaj   +1 more source

PexRAP inhibits PRDM16-mediated thermogenic gene expression [PDF]

open access: yes, 2017
How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat, as well as the browning of white fat, remains unclear.
Dean, John M   +8 more
core   +3 more sources

Development of brown and white adipose tissue

open access: yesJournal of Lipid Research, 1975
In this review, it is assumed that the reader is familiar with the basic properties of white and brown adipose tissue. The role and metabolic characteristics of both tissues in adult mammals have been adequately and repeatedly reviewed (1-3) and will be mentioned here only insofar as they impinge upon developmental aspects. Macroscopically brown fat is
Peter Hahn, Milan Novák
openaire   +4 more sources

The regulation of adipocyte growth in white adipose tissue

open access: yesFrontiers in Cell and Developmental Biology, 2022
Adipocytes can increase in volume up to a thousand-fold, storing excess calories as triacylglycerol in large lipid droplets. The dramatic morphological changes required of adipocytes demands extensive cytoskeletal remodeling, including lipid droplet and plasma membrane expansion.
Li, Qian, Spalding, Kirsty L.
openaire   +3 more sources

AATCT-IDS: A Benchmark Abdominal Adipose Tissue CT Image Dataset for Image Denoising, Semantic Segmentation, and Radiomics Evaluation [PDF]

open access: yesarXiv, 2023
Methods: In this study, a benchmark \emph{Abdominal Adipose Tissue CT Image Dataset} (AATTCT-IDS) containing 300 subjects is prepared and published. AATTCT-IDS publics 13,732 raw CT slices, and the researchers individually annotate the subcutaneous and visceral adipose tissue regions of 3,213 of those slices that have the same slice distance to ...
arxiv  

Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming [PDF]

open access: yes, 2017
BACKGROUND: The de novo biosynthesis of fatty acids (DNL) through fatty acid synthase (FASN) in adipocytes is exquisitely regulated by nutrients, hormones, fasting, and obesity in mice and humans. However, the functions of DNL in adipocyte biology and in
Czech, Michael P   +11 more
core   +4 more sources

Fate of Adipose Progenitor Cells in Obesity-Related Chronic Inflammation [PDF]

open access: yes, 2020
Adipose progenitor cells, or preadipocytes, constitute a small population of immature cells within the adipose tissue. They are a heterogeneous group of cells, in which different subtypes have a varying degree of commitment toward diverse cell fates ...
Chatzigeorgiou , Antonios   +5 more
core   +1 more source

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