Results 41 to 50 of about 253,274 (360)

Roles of FGFs as adipokines in adipose tissue development, remodeling, and metabolism

open access: yesFrontiers in Endocrinology, 2014
White and brown adipose tissues, which store and burn lipids, respectively, play critical roles in energy homeostasis. Fibroblast growth factors (FGFs) are signaling proteins with diverse functions in development, metabolism, and neural function. Among
Nobuyuki eItoh, Hiroya eOhta
doaj   +1 more source

Latest Advancements on Combating Obesity by Targeting Human Brown/Beige Adipose Tissues

open access: yesFrontiers in Endocrinology, 2022
Obesity is defined as overaccumulation of white adipose tissue in the body, mainly under the skin (subcutaneous adiposity) or in the abdominal cavity (visceral adiposity).
Ruping Pan   +3 more
doaj   +1 more source

Gene Expression Analysis of Murine Brown and Subcutaneous Adipose Tissue: Significance with Human

open access: yesОжирение и метаболизм, 2015
Gene Expression Analysis of Murine Brown and Subcutaneous Adipose Tissue: Significance with ...
Teona Albertovna Shvangiradze
doaj   +1 more source

Otopetrin 1 protects mice from obesity-associated metabolic dysfunction through attenuating adipose tissue inflammation. [PDF]

open access: yes, 2014
Chronic low-grade inflammation is emerging as a pathogenic link between obesity and metabolic disease. Persistent immune activation in white adipose tissue (WAT) impairs insulin sensitivity and systemic metabolism, in part, through the actions of ...
Cheng, Ji-Xin   +10 more
core   +2 more sources

Spatial Metabolomics Reveals the Effects of Dietary Capsaicin Intervention on Interscapular Adipose Tissue Metabolome in Mice

open access: yesFoods
Capsaicin is a polyphenol with a well-known anti-obesity potential, which could activate brown adipose tissue and promote the browning of white adipose tissue.
Haoqing Yang   +5 more
doaj   +1 more source

Characterisation of human adipose tissue : ceramide metabolism, depot differences and evaluation of dysfunctionality [PDF]

open access: yes, 2016
Normal adipose tissue function is necessary for maintaining proper energy balance, as both excess and absence of this tissue lead to metabolic disturbances, such as insulin resistance.
Gertow, Joanna
core   +1 more source

Effects of Different Fasting Modes Combined with Exercise Training on Browning of White Adipose Tissue in Mice [PDF]

open access: yesShipin Kexue
To investigate the effect of intermittent fasting (IF) combined with exercise on browning of white adipose tissue (WAT), we randomly divided male C57BL/6 mice aged 5–6 weeks into six groups: control (Con), exercise (Ex), alternate-day fasting (ADF ...
LI Yinhuan, WANG Xukai, SHI Jian, XU Linjing, ZHOU Lizi, LI Weiye, LIU Hui, LIU Chunhong
doaj   +1 more source

Ethnic differences in adiposity and diabetes risk – insights from genetic studies [PDF]

open access: yes, 2020
Type 2 diabetes is more common in non-Europeans and starts at a younger age and at lower BMI cut-offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of disease with a focus on the role of
Bell, J.D.   +7 more
core   +2 more sources

E0771 and 4T1 murine breast cancer cells and interleukin 6 alter gene expression patterns but do not induce browning in cultured white adipocytes

open access: yesBiochemistry and Biophysics Reports, 2019
Breast cancer remains a substantial clinical problem worldwide, and cancer-associated cachexia is a condition associated with poor prognosis in this and other malignancies.
Janina V. Pearce   +6 more
doaj   +1 more source

Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus

open access: yesAdipocyte, 2021
Mammalian adipose tissue can be divided into two major types, namely, white adipose tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function of WAT is to store excess energy in the form of triglycerides, while BAT is a ...
Long Cheng   +13 more
doaj   +1 more source

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