Results 21 to 30 of about 4,384,512 (209)

RIP140 represses the “Brown-in-White” adipocyte program including a futile cycle of triacyclglycerol breakdown and synthesis [PDF]

open access: yes, 2014
Receptor-interacting protein 140 (RIP140) is a corepressor of nuclear receptors that is highly expressed in adipose tissues. We investigated the role of RIP140 in conditionally immortal preadipocyte cell lines prepared from white or brown fat depots.
Edward Curry   +25 more
core   +1 more source

Adipose-derived mesenchymal stromal/stem cells : tissue localization, characterization, and heterogeneity [PDF]

open access: yes, 2012
Adipose tissue as a stem cell source is ubiquitously available and has several advantages compared to other sources. It is easily accessible in large quantities with minimal invasive harvesting procedure, and isolation of adipose-derived mesenchymal ...
Helmut Geiger   +3 more
core   +1 more source

De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis

open access: yesNature Communications, 2018
Long non-coding RNAs are known to regulate mouse white adipose tissue development and brown adipose tissue program expression. Here, the authors construct a roadmap for human long non-coding RNAs expressed in fetal brown adipose tissue, adult omental and
Chunming Ding   +12 more
doaj   +1 more source

Expression profiles and gene set enrichment analysis of the transcriptomes from the cancer tissue, white adipose tissue and paracancer tissue with colorectal cancer [PDF]

open access: yesPeerJ
Background Colorectal cancer (CRC) is one of the most common cancers worldwide and is related to diet and obesity. Currently, crosstalk between lipid metabolism and CRC has been reported; however, the specific mechanism is not yet understood.
Xiufeng Zhang   +9 more
doaj   +2 more sources

CD47 differentially regulates white and brown fat function

open access: yesBiology Open, 2020
Mechanisms that enhance energy expenditure are attractive therapeutic targets for obesity. Previously we have demonstrated that mice lacking cd47 are leaner, exhibit increased energy expenditure, and are protected against diet-induced obesity.
Heather Norman-Burgdolf   +3 more
doaj   +1 more source

Adipokines: inflammation and the pleiotropic role of white adipose tissue. [PDF]

open access: yes, 2022
I had been working on the endocrine and signalling role of white adipose tissue (WAT) since 1994 following the identification of the ob (Lep) gene(1), this after some 15 years investigating the physiological role of brown adipose tissue.
Trayhurn, Paul
core   +1 more source

The adipose tissue: something more than a reservoir of energy

open access: yesGrasas y Aceites, 2009
Adipose tissue is a reservoir of energy and also an organ that contributes to the aesthetics and health of human body working as an endocrine tissue. White adipose tissue, which is formed by unilocular adipose cells, can modify organic homeostasis by ...
Alfonso Valenzuela B, Julio Sanhueza C
doaj   +1 more source

mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue [PDF]

open access: yes, 2016
Activation of non-shivering thermogenesis (NST) in brown adipose tissue (BAT) has been proposed as an anti-obesity treatment. Moreover, cold-induced glucose uptake could normalize blood glucose levels in insulin-resistant patients.
Handschin, Christoph   +20 more
core   +1 more source

Spatial Metabolomics Reveals the Effects of Dietary Capsaicin Intervention on Interscapular Adipose Tissue Metabolome in Mice

open access: yesFoods
Capsaicin is a polyphenol with a well-known anti-obesity potential, which could activate brown adipose tissue and promote the browning of white adipose tissue.
Haoqing Yang   +5 more
doaj   +1 more source

Gene Expression Analysis of Murine Brown and Subcutaneous Adipose Tissue: Significance with Human

open access: yesОжирение и метаболизм, 2015
Gene Expression Analysis of Murine Brown and Subcutaneous Adipose Tissue: Significance with ...
Teona Albertovna Shvangiradze
doaj   +1 more source

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