Results 51 to 60 of about 116,442 (217)

FAM13A and POM121C are candidate genes for fasting insulin: functional follow-up analysis of a genome-wide association study [PDF]

, 2018
Aims/hypothesis: By genome-wide association meta-analysis, 17 genetic loci associated with fasting serum insulin (FSI), a marker of systemic insulin resistance, have been identified. To define potential culprit genes in these loci, in a cross-sectional
Arner, Peter, Dahlman, Ingrid, Kulyte, Agne, Lundbäck, Veroniqa, Marcus, Claude, Ryden, Mikael, Strawbridge, Rona J.   +6 more
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Sox9-Meis1 Inactivation Is Required for Adipogenesis, Advancing Pref-1+ to PDGFRα+ Cells. [PDF]

, 2018
Adipocytes arise from the commitment and differentiation of adipose precursors in white adipose tissue (WAT). In studying adipogenesis, precursor markers, including Pref-1 and PDGFRα, are used to isolate precursors from stromal vascular fractions of WAT,
Gulyaeva, Olga, Heydari, Kartoosh, Nguyen, Hai, Sambeat, Audrey, Sul, Hei Sook   +4 more
core   +1 more source

Water-fat magnetic resonance imaging of adipose tissue compartments in the normal third trimester fetus [PDF]

, 2021
BACKGROUND: Assessment of fetal adipose tissue gives information about the future metabolic health of an individual, with evidence that the development of this tissue has regional heterogeneity.
de Vrijer, Barbra, Eastabrook, Genevieve D, Giza, Stephanie A, Koreman, Tianna L, McKenzie, Charles A, Miller, Michael R, Penava, Debbie A, Sethi, Simran   +7 more
core   +2 more sources

Pyrophosphate‐Containing Calcium Phosphates Negatively Impact Heterotopic Bone Quality

Advanced Healthcare Materials, EarlyView.
The role of calcium pyrophosphate (Ca‐PP) in heterotopic bone formation and material degradation is investigated using calcium phosphate (CaP) compositions with varying Ca‐PP content. Results show that Ca‐PP does not impede heterotopic bone formation, minimally affects CaP degradation at non‐osseous sites, and increases phagocytosis.
Martina Jolic, Isabella Åberg, Omar Omar, Håkan Engqvist, Thomas Engstrand, Anders Palmquist, Peter Thomsen, Furqan A. Shah   +7 more
wiley   +1 more source

Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ [PDF]

Proceedings of the Nutrition Society, 2001
The traditional role attributed to white adipose tissue is energy storage, fatty acids being released when fuel is required. The metabolic role of white fat is, however, complex. For example, the tissue is needed for normal glucose homeostasis and a role in inflammatory processes has been proposed. A radical change in perspective followed the discovery
John H. Beattie, Paul Trayhurn
openaire   +3 more sources

Characterization of Cre recombinase models for the study of adipose tissue [PDF]

, 2014
The study of adipose tissue in vivo has been significantly advanced through the use of genetic mouse models. While the aP2-CreBI and aP2-CreSalk lines have been widely used to target adipose tissue, the specificity of these lines for adipocytes has ...
Berry, Ryan, Church, Christopher D, Horsley, Valerie, Jeffery, Elise, Rodeheffer, Matthew S, Rosen, Evan D, Shook, Brett A, Yu, Songtao   +7 more
core   +1 more source

Tri‐Layered Bioactive Cutaneous Scaffold with Integrated Bioactive Metal Organic Frameworks to Promote Full‐Thickness Infected Diabetic Wound Healing: Multifaceted Therapeutic Strategies

Advanced Healthcare Materials, EarlyView.
The limitations of existing clinical treatments highlight the need for a more comprehensive strategy for addressing infected diabetic wounds. A tri‐layered scaffold is developed to deliver therapeutics loaded in CuBDC and ZIF‐8 MOFs that are tailored to the requirements of deep‐infected diabetic wounds.
Ayse Gunyakti Mujtaba, Ayşe Karakeçili, Berna Topuz, Barış Batur, Okan Onar, Mehmet Eray Elçiğir, Çağdaş Oto, Alireza Hanifehnezhad, Kaan Orhan   +8 more
wiley   +1 more source

Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk [PDF]

, 2019
BACKGROUND: Muscle wasting from chronic kidney disease (CKD) or from defective insulin signalling results in morbidity and, ultimately, mortality. We have identified an endogenous mediator of insulin resistance, signal regulatory protein alpha (SIRPα ...
Dong, Jiangling, Garibotto, Giacomo, Hruska, Keith, Hu, Zhaoyong, Mitch, William E, Thomas, Sandhya S, Verzola, Daniela, Wu, Jiao   +7 more
core   +2 more sources

Lytic cocktail:An effective method to alleviate severe burn induced hyper-metabolism through regulating white adipose tissue browning [PDF]

, 2022
Background: Browning of white adipose tissue is associated with elevated resting metabolic rates and is considered to be one of the indispensable causes of hypermetabolism in burn patients.
Gao, Min, Harmsen, Martin C., Liu, Dan, Liu, Yan, Shi, Yan, Yang, Peilang, Yu, Tianyi, Zhang, Meng, Zhang, Xiong   +8 more
core   +1 more source