Results 51 to 60 of about 254,914 (259)

Roles of FGFs as adipokines in adipose tissue development, remodeling, and metabolism

open access: yesFrontiers in Endocrinology, 2014
White and brown adipose tissues, which store and burn lipids, respectively, play critical roles in energy homeostasis. Fibroblast growth factors (FGFs) are signaling proteins with diverse functions in development, metabolism, and neural function. Among
Nobuyuki eItoh, Hiroya eOhta
doaj   +1 more source

Unraveling White Adipose Tissue Heterogeneity and Obesity by Adipose Stem/Stromal Cell Biology and 3D Culture Models

open access: yesCells, 2023
The immune and endocrine dysfunctions of white adipose tissue are a hallmark of metabolic disorders such as obesity and type 2 diabetes. In humans, white adipose tissue comprises distinct depots broadly distributed under the skin (hypodermis) and as ...
Leandra S. Baptista   +4 more
doaj   +1 more source

Global gene expression profiling of brown to white adipose tissue transformation in sheep reveals novel transcriptional components linked to adipose remodeling [PDF]

open access: yes, 2015
BACKGROUND: Large mammals are capable of thermoregulation shortly after birth due to the presence of brown adipose tissue (BAT). The majority of BAT disappears after birth and is replaced by white adipose tissue (WAT).
Basse, Astrid L.   +9 more
core   +3 more sources

Spatial Metabolomics Reveals the Effects of Dietary Capsaicin Intervention on Interscapular Adipose Tissue Metabolome in Mice

open access: yesFoods
Capsaicin is a polyphenol with a well-known anti-obesity potential, which could activate brown adipose tissue and promote the browning of white adipose tissue.
Haoqing Yang   +5 more
doaj   +1 more source

Epigenetic regulation of white adipose tissue plasticity and energy metabolism by nucleosome binding HMGN proteins

open access: yesNature Communications, 2022
White adipose tissue browning plays an important role in regulating whole-body energy homeostasis and metabolism. Here the authors show that the HMGN nucleosome binding proteins epigenetically promote white adipocyte differentiation and modulate the rate
Ravikanth Nanduri   +9 more
doaj   +1 more source

Latest Advancements on Combating Obesity by Targeting Human Brown/Beige Adipose Tissues

open access: yesFrontiers in Endocrinology, 2022
Obesity is defined as overaccumulation of white adipose tissue in the body, mainly under the skin (subcutaneous adiposity) or in the abdominal cavity (visceral adiposity).
Ruping Pan   +3 more
doaj   +1 more source

Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice [PDF]

open access: yes, 2016
The present study aimed to determine the effect of thyroid hormone dysfunction on brown adipose tissue activity and white adipose tissue browning in mice.
Hankir, Mohammed [u.v.m.]   +8 more
core   +1 more source

Effects of Different Fasting Modes Combined with Exercise Training on Browning of White Adipose Tissue in Mice [PDF]

open access: yesShipin Kexue
To investigate the effect of intermittent fasting (IF) combined with exercise on browning of white adipose tissue (WAT), we randomly divided male C57BL/6 mice aged 5–6 weeks into six groups: control (Con), exercise (Ex), alternate-day fasting (ADF ...
LI Yinhuan, WANG Xukai, SHI Jian, XU Linjing, ZHOU Lizi, LI Weiye, LIU Hui, LIU Chunhong
doaj   +1 more source

Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus

open access: yesAdipocyte, 2021
Mammalian adipose tissue can be divided into two major types, namely, white adipose tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function of WAT is to store excess energy in the form of triglycerides, while BAT is a ...
Long Cheng   +13 more
doaj   +1 more source

Characterization of Cre recombinase models for the study of adipose tissue [PDF]

open access: yes, 2014
The study of adipose tissue in vivo has been significantly advanced through the use of genetic mouse models. While the aP2-CreBI and aP2-CreSalk lines have been widely used to target adipose tissue, the specificity of these lines for adipocytes has ...
Berry, Ryan   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy