Results 51 to 60 of about 499,911 (300)

De novo reconstruction of human adipose transcriptome reveals conserved lncRNAs as regulators of brown adipogenesis

Nature Communications, 2018
Long non-coding RNAs are known to regulate mouse white adipose tissue development and brown adipose tissue program expression. Here, the authors construct a roadmap for human long non-coding RNAs expressed in fetal brown adipose tissue, adult omental and
Chunming Ding, Yen Ching Lim, Sook Yoong Chia, Arcinas Camille Esther Walet, Shaohai Xu, Kinyui Alice Lo, Yanling Zhao, Dewen Zhu, Zhihui Shan, Qingfeng Chen, Melvin Khee-Shing Leow, Dan Xu, Lei Sun   +12 more
doaj   +1 more source

Expression profiles and gene set enrichment analysis of the transcriptomes from the cancer tissue, white adipose tissue and paracancer tissue with colorectal cancer [PDF]

PeerJ
Background Colorectal cancer (CRC) is one of the most common cancers worldwide and is related to diet and obesity. Currently, crosstalk between lipid metabolism and CRC has been reported; however, the specific mechanism is not yet understood.
Xiufeng Zhang, Rui Zhu, Ye Jiao, Halizere Simayi, Jialing He, Zhong Shen, Houdong Wang, Jun He, Suzhan Zhang, Fei Yang   +9 more
doaj   +2 more sources

CD47 differentially regulates white and brown fat function

Biology Open, 2020
Mechanisms that enhance energy expenditure are attractive therapeutic targets for obesity. Previously we have demonstrated that mice lacking cd47 are leaner, exhibit increased energy expenditure, and are protected against diet-induced obesity.
Heather Norman-Burgdolf, Dong Li, Patrick Sullivan, Shuxia Wang   +3 more
doaj   +1 more source

Beige Adipose Tissue Identification and Marker Specificity—Overview

Frontiers in Endocrinology, 2021
Adipose tissue (AT) is classified based on its location, physiological and functional characteristics. Although there is a clear demarcation of anatomical and molecular features specific to white (WAT) and brown adipose tissue (BAT), the factors that ...
Anna-Claire Pilkington, Henry A. Paz, Henry A. Paz, Umesh D. Wankhade, Umesh D. Wankhade   +4 more
doaj   +1 more source

Regulatory microRNAs in Brown, Brite and White Adipose Tissue

Cells, 2020
MicroRNAs (miRNAs) constitute a class of short noncoding RNAs which regulate gene expression by targeting messenger RNA, inducing translational repression and messenger RNA degradation.
S. Gharanei, K. Shabir, James E. Brown, M. Weickert, T. Barber, I. Kyrou, H. Randeva   +6 more
semanticscholar   +1 more source

Polyunsaturated fatty acids stimulate de novo lipogenesis and improve glucose homeostasis during refeeding with high fat diet [PDF]

, 2017
The recovery of body weight after a period of caloric restriction is accompanied by an enhanced efficiency of fat deposition and hyperinsulinemia—which are exacerbated by isocaloric refeeding on a high fat diet rich in saturated and monounsaturated ...
Bianco, Francesca, Cancelliere, Rosa, Crescenzo, Raffaella, Dulloo, Abdul G., Giacco, Antonia, Iossa, Susanna, Liverini, Giovanna, Mazzoli, Arianna   +7 more
core   +1 more source

The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs

Science Translational Medicine, 2019
Tryptophan-derived metabolites from the gut microbiota control miR-181 expression in mouse white adipocytes to regulate metabolism and inflammation.
A. Virtue, S. McCright, Jasmine M Wright, M. T. Jimenez, Walter K. Mowel, Jonathan J Kotzin, Leonel Joannas, Megha Basavappa, S. Spencer, M. Clark, S. Eisennagel, Adam Williams, M. Levy, M. Levy, Sasikanth Manne, S. Henrickson, S. Henrickson, E. Wherry, Christoph A. Thaiss, Christoph A. Thaiss, E. Elinav, Jorge Henao-Mejia, Jorge Henao-Mejia   +22 more
semanticscholar   +1 more source

Spatial Metabolomics Reveals the Effects of Dietary Capsaicin Intervention on Interscapular Adipose Tissue Metabolome in Mice

Foods
Capsaicin is a polyphenol with a well-known anti-obesity potential, which could activate brown adipose tissue and promote the browning of white adipose tissue.
Haoqing Yang, Peiying Zheng, Jiamiao Hu, Zhongjing Lin, Natthida Sriboonvorakul, Shaoling Lin   +5 more
doaj   +1 more source

Otopetrin 1 protects mice from obesity-associated metabolic dysfunction through attenuating adipose tissue inflammation. [PDF]

, 2014
Chronic low-grade inflammation is emerging as a pathogenic link between obesity and metabolic disease. Persistent immune activation in white adipose tissue (WAT) impairs insulin sensitivity and systemic metabolism, in part, through the actions of ...
Cheng, Ji-Xin, Cho, Kae Won, Cozacov, Zoharit, Hu, Chun-Rui, Li, Siming, Lin, Jiandie D, Lumeng, Carey N, Saltiel, Alan R, Uhm, Maeran, Wang, Guo-Xiao, Xu, Acer E   +10 more
core   +2 more sources

Fibroblast Growth Factor 21 and Browning of White Adipose Tissue

Frontiers in Physiology, 2019
Interest has been focused on differentiating anatomical, molecular, and physiological characteristics of the types of mammalian adipose tissues. White adipose tissue (WAT) and brown adipose tissue (BAT) are the two main forms of adipose tissue in humans.
R. Matteis, D. Cuevas-Ramos, R. Mehta, C. Aguilar-Salinas   +3 more
semanticscholar   +1 more source