Results 61 to 70 of about 388,905 (379)

Effects of Different Fasting Modes Combined with Exercise Training on Browning of White Adipose Tissue in Mice [PDF]

Shipin Kexue
To investigate the effect of intermittent fasting (IF) combined with exercise on browning of white adipose tissue (WAT), we randomly divided male C57BL/6 mice aged 5–6 weeks into six groups: control (Con), exercise (Ex), alternate-day fasting (ADF ...
LI Yinhuan, WANG Xukai, SHI Jian, XU Linjing, ZHOU Lizi, LI Weiye, LIU Hui, LIU Chunhong
doaj   +1 more source

Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus

Adipocyte, 2021
Mammalian adipose tissue can be divided into two major types, namely, white adipose tissue (WAT) and brown adipose tissue (BAT). According to classical view, the main function of WAT is to store excess energy in the form of triglycerides, while BAT is a ...
Long Cheng, Jingkang Wang, Hongyu Dai, Yuhui Duan, Yongcheng An, Lu Shi, Yinglan Lv, Huimin Li, Chen Wang, Quantao Ma, Yaqi Li, Pengfei Li, Haifeng Du, Baosheng Zhao   +13 more
doaj   +1 more source

Otopetrin 1 protects mice from obesity-associated metabolic dysfunction through attenuating adipose tissue inflammation. [PDF]

, 2014
Chronic low-grade inflammation is emerging as a pathogenic link between obesity and metabolic disease. Persistent immune activation in white adipose tissue (WAT) impairs insulin sensitivity and systemic metabolism, in part, through the actions of ...
Cheng, Ji-Xin, Cho, Kae Won, Cozacov, Zoharit, Hu, Chun-Rui, Li, Siming, Lin, Jiandie D, Lumeng, Carey N, Saltiel, Alan R, Uhm, Maeran, Wang, Guo-Xiao, Xu, Acer E   +10 more
core   +2 more sources

Association of environmental exposure to perchlorate, nitrate, and thiocyanate with overweight/obesity and central obesity among children and adolescents in the United States of America using data from the National Health and Nutrition Examination Survey (NHANES) 2005–2016

New Directions for Child and Adolescent Development, Volume 2022, Issue 185-186, Page 107-122, November 2022., 2022
Abstract The association of overweight/obesity, and central obesity with thiocyanate (SCN), perchlorate (CIO), and nitrate (NO) in childhood and adolescence is unclear. Therefore, this study aimed to explore this association in 4447 participants comprising children and adolescents (aged 6–19 years) using data from the United States National Health and ...
Qi Jiang, Qin Li
wiley   +1 more source

UCP1 Induction during Recruitment of Brown Adipocytes in White Adipose Tissue Is Dependent on Cyclooxygenase Activity [PDF]

, 2010
Background The uncoupling protein 1 (UCP1) is a hallmark of brown adipocytes and pivotal for cold- and diet-induced thermogenesis. Methodology/Principal Findings Here we report that cyclooxygenase (COX) activity and prostaglandin E2 (PGE2) are crucially ...
A Cederberg, A Cederberg, AE Stenbit, Aimin Xu, AK Bauer, AM Cypess, B Cannon, B Cannon, B Razani, Barbara Cannon, BT Hyman, C Guerra, C Guerra, C Guerra, C Guerra, CJ Narvaez, D Grujic, DE Cummings, DE Cummings, Even Fjære, F Picard, F Ushikubi, G Garruti, G Leonardsson, G Vassaux, H Oberkofler, H Oberkofler, H Oberkofler, H Oberkofler, Haldis Haukaas Lillefosse, HD Gaskins, HM Feldmann, HM Feldmann, Ingeborg Bronstad, J Himms-Hagen, J Kopecky, J Kopecky, J Kopecky, J Kopecky, J Kopecky, J Mercader, JA Timmons, Jacob B. Hansen, Jan Nedergaard, JB Hansen, JB Hansen, JB Hansen, JB Hansen, JB Hansen, JB Hansen, JB Hansen, JG Granneman, JG Granneman, JN Fain, Josep Mercader, Jun Wang, K Muller-Decker, K Ström, K Tsukiyama-Kohara, KA Virtanen, Karsten Kristiansen, L Madsen, L Madsen, L Madsen, L Madsen, L Madsen, Lise Madsen, Lone M. Pedersen, M Abramovitz, M Jimenez, M Jimenez, M Saito, M. Luisa Bonet, MA Nolan, MC Zingaretti, ME Lean, N Dali-Youcef, N Petrovic, NJ Rothwell, P Seale, P Seale, Pedro Araujo, Peter Voshol, Philip Hallenborg, PM Watson, PM Watson, PM Watson, PO Hetu, Qin Hao, RA Koza, Rasmus K. Petersen, Rita De Matteis, RK Petersen, RK Semple, S Cinti, S Cinti, S Collins, S Enerbäck, Saverio Cinti, SG Morham, Stein Ove Døskeland, SY Toh, T Kunikata, Tao Ma, WD van Marken Lichtenbelt, Y Sakuma, YH Tseng, Z Zhou   +107 more
core   +13 more sources

Roles of FGFs as adipokines in adipose tissue development, remodeling, and metabolism

Frontiers in Endocrinology, 2014
White and brown adipose tissues, which store and burn lipids, respectively, play critical roles in energy homeostasis. Fibroblast growth factors (FGFs) are signaling proteins with diverse functions in development, metabolism, and neural function. Among
Nobuyuki eItoh, Hiroya eOhta
doaj   +1 more source

Unraveling White Adipose Tissue Heterogeneity and Obesity by Adipose Stem/Stromal Cell Biology and 3D Culture Models

Cells, 2023
The immune and endocrine dysfunctions of white adipose tissue are a hallmark of metabolic disorders such as obesity and type 2 diabetes. In humans, white adipose tissue comprises distinct depots broadly distributed under the skin (hypodermis) and as ...
Leandra S. Baptista, Karina R. Silva, Lara Jobeili, Lucile Guillot, Dominique Sigaudo-Roussel   +4 more
doaj   +1 more source

Cold-induced lipid dynamics and transcriptional programs in white adipose tissue

BMC Biology, 2019
In mammals, cold exposure induces browning of white adipose tissue (WAT) and alters WAT gene expression and lipid metabolism to boost adaptive thermogenesis and maintain body temperature.
Ziye Xu, Wenjing You, Yanbing Zhou, Wentao Chen, Yizhen Wang, T. Shan   +5 more
semanticscholar   +1 more source

Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning [PDF]

, 2019
Type-2 Familial Partial Lipodystrophy is caused by LMNA mutations. Patients gradually lose subcutaneous fat from the limbs, while they accumulate adipose tissue in the face and neck.
A Armani, A Giordano, A Infante, A Koppen, Alessandra Gambineri, AM Cypess, AM Cypess, Assuero Giorgetti, B Gustafson, C Capanni, C Capanni, C Capanni, C Evangelisti, C Le Dour, C Vigouroux, C Zhang, Camilla Pellegrini, CH Choi, Cristina Capanni, CS Patlak, CY Liao, D Araujo-Vilar, D Camozzi, D Dorner, D Li, David Araujo-Vilar, Davide Andrenacci, DG Batrakou, DJ Klionsky, E Mattioli, E Mattioli, Elisa Schena, Elisabetta Mattioli, FJ Ramos, G Bidault, G Lattanzi, G Ruiz de Eguino, Giovanna Lattanzi, HM Ni, J Orava, JC Choi, JC Choi, K Cao, K Frondorf, K Liu, KA Virtanen, Laura Zanotti, M Caron, M Friesen, Manuela Loi, Maria Angela Guzzardi, Marta Columbaro, MC Zingaretti, N Lehman, N Mizushima, N Patni, P Bernasconi, P Cohen, Paolo Morselli, Patricia Iozzo, R Singh, RJ Brown, RL Boguslavsky, S Cinti, S Dominici, S Goldman, S Rodriguez-Acebes, Sabino Prencipe, Saverio Cinti, SJ Goldman, Stefano Squarzoni, V Bereziat, V Cenni, V Cenni, V Garcia-Alonso, V Ouellet, V Ouellet, Y Liu, Z Dou   +78 more
core   +2 more sources

Lipolysis and lipases in white adipose tissue – An update [PDF]

Archives of Endocrinology and Metabolism, 2015
Lipolysis is defined as the sequential hydrolysis of triacylglycerol (TAG) stored in cell lipid droplets. For many years, it was believed that hormone-sensitive lipase (HSL) and monoacylglycerol lipase (MGL) were the main enzymes catalyzing lipolysis in the white adipose tissue.
Bolsoni-Lopes, Andressa, Alonso-Vale, Maria Isabel C.   +1 more
openaire   +6 more sources