Results 1 to 10 of about 6,982,631 (374)
Therapeutic Advances in Neurological Disorders, 2012 White matter dementia (WMD) is a syndrome introduced in 1988 to highlight the potential of cerebral white matter disorders to produce cognitive loss of sufficient severity to qualify as dementia. Neurologists have long understood that such a syndrome can
Christopher M. Filley
doaj +3 more sources
White Matter-Gray Matter Correlation Analysis Based on White Matter Functional Gradient
Brain SciencesBackground: The spontaneous fluctuations in functional magnetic resonance imaging (fMRI) signals of the brain’s gray matter (GM) have been interpreted as representations of neural activity variations.
Zhengjie Li +5 more
doaj +2 more sources
Definitions, 2020 T he nerve tissue forming the bulk of the deep parts of the brain and the superficial parts of the spinal cord. It is composed of nerve cell processes, i.e.
openaire +2 more sources
CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging
Nature Neuroscience, 2022 A hallmark of nervous system aging is a decline of white matter volume and function, but the underlying mechanisms leading to white matter pathology are unknown.
Tugberk Kaya +13 more
semanticscholar +1 more source
Common genetic variation influencing human white matter microstructure
Science, 2021 Connecting the dots on white matter The white matter of the brain, which is composed of axonal tracts connecting different brain regions, plays key roles in both normal brain function and a variety of neurological disorders. Zhao et al. combined detailed
Bingxin Zhao +14 more
semanticscholar +1 more source
White matter changes underlie hypertension-related cognitive decline in older adults
NeuroImage: Clinical, 2023 Hypertension has been well recognized as a risk factor for cognitive impairment and dementia. Although the underlying mechanisms of hypertension-affected cognitive deterioration are not fully understood, white matter changes (WMCs) seem to play an ...
Zilin Li +4 more
doaj +1 more source
Regional vulnerability of brain white matter in vanishing white matter
Acta Neuropathologica Communications, 2023 Vanishing white matter (VWM) is a leukodystrophy that primarily manifests in young children. In this disease, the brain white matter is differentially affected in a predictable pattern with telencephalic brain areas being most severely affected, while ...
Jodie H.K. Man +7 more
doaj +1 more source
What's the Matter? White Matter? [PDF]
Neuron, 2000 Although many children acquire reading skills rapidly with some formal training, for others learning to read is among the most difficult challenges they face in the first few years at school. The reasons for these large individual differences in skill acquisition are still obscure, with the relative contribution of biological and environmental factors ...
Zeffiro, Thomas, Eden, Guinevere
openaire +2 more sources
Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion
Theranostics, 2020 Microglial activation participates in white matter injury after cerebral hypoperfusion. However, the underlying mechanism is unclear. Here, we explore whether activated microglia aggravate white matter injury via complement C3-C3aR pathway after chronic ...
Lin-Yuan Zhang +11 more
semanticscholar +1 more source
Metachromatic leukodystrophy and transplantation: remyelination, no cross‐correction
Annals of Clinical and Translational Neurology, 2020 Objective In metachromatic leukodystrophy, a lysosomal storage disorder due to decreased arylsulfatase A activity, hematopoietic stem cell transplantation may stop brain demyelination and allow remyelination, thereby halting white matter degeneration ...
Nicole I. Wolf +15 more
doaj +1 more source