Results 11 to 20 of about 4,186,199 (340)
Microglia exacerbate white matter injury via complement C3/C3aR pathway after hypoperfusion
Theranostics, 2020 Microglial activation participates in white matter injury after cerebral hypoperfusion. However, the underlying mechanism is unclear. Here, we explore whether activated microglia aggravate white matter injury via complement C3-C3aR pathway after chronic ...
Linyuan Zhang +11 more
semanticscholar +1 more source
Metachromatic leukodystrophy and transplantation: remyelination, no cross‐correction
Annals of Clinical and Translational Neurology, 2020 Objective In metachromatic leukodystrophy, a lysosomal storage disorder due to decreased arylsulfatase A activity, hematopoietic stem cell transplantation may stop brain demyelination and allow remyelination, thereby halting white matter degeneration ...
Nicole I. Wolf +15 more
doaj +1 more source
Association between Perivascular Spaces and Progression of White Matter Hyperintensities in Lacunar Stroke Patients. [PDF]
PLoS ONE, 2015 Perivascular spaces are associated with MRI markers of cerebral small vessel disease, including white matter hyperintensities. Although perivascular spaces are considered to be an early MRI marker of cerebral small vessel disease, it is unknown whether ...
Caroline M J Loos +3 more
doaj +1 more source
Increased functional connectivity of white-matter in myotonic dystrophy type 1
Frontiers in Neuroscience, 2022 BackgroundMyotonic dystrophy type 1 (DM1) is the most common and dominant inherited neuromuscular dystrophy disease in adults, involving multiple organs, including the brain.
Jing Li +21 more
doaj +1 more source
Vanishing white matter disease [PDF]
Paediatria Croatica, 2006 Vanishing White Matter Disease (VWMD) is one of the most prevalent inherited white matter disorders in childhood, with a large variety in the age of onset and rate of progression. The classical and most common type shows its onset between the ages of 2 and 6 years in children with initially normal motor and mental development.
Mejaski-Bosnjak, V. +5 more
openaire +5 more sources
Frontiers in Neurology, 2019 Background: The clinical significance of cerebral white matter hyperintensities (WMH) on brain magnetic resonance imaging (MRI) has recently increased, and recognized now as a risk factor for future stroke and dementia. High levels of plasma homocysteine
Kee Ook Lee +6 more
doaj +1 more source
The Microvasculature of the Cerebral White Matter: Arteries of the Subcortical White Matter [PDF]
Journal of Neuropathology & Experimental Neurology, 2003 The microvascular architecture of the human cerebral subcortical white matter was studied. Most of the subcortical arteries ran straight through the cortex, but upon entering the white matter, they began to coil, loop, and spiral. Vascular stains showed wide spaces between the adventitial sheaths and blood vessels. The blood vessels coiled, looped, and
Zean Zhang +5 more
openaire +3 more sources
White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes
Acta Neuropathologica Communications, 2018 Alzheimer’s disease (AD) is conceptualized as a progressive consequence of two hallmark pathological changes in grey matter: extracellular amyloid plaques and neurofibrillary tangles.
S. E. Nasrabady +3 more
semanticscholar +1 more source
Rethinking the standard trans-cortical approaches in the light of superficial white matter anatomy
Neural Regeneration Research, 2015 A better comprehension of the superficial white matter organization is important in order to minimize potential and avoidable damage to long or intermediate association fibre bundles during every step of a surgical approach.
Francesco Latini, Mats Ryttlefors
doaj +1 more source
White matter changes underlie hypertension-related cognitive decline in older adults
NeuroImage: Clinical, 2023 Hypertension has been well recognized as a risk factor for cognitive impairment and dementia. Although the underlying mechanisms of hypertension-affected cognitive deterioration are not fully understood, white matter changes (WMCs) seem to play an ...
Zilin Li +4 more
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