Regional vulnerability of brain white matter in vanishing white matter
Vanishing white matter (VWM) is a leukodystrophy that primarily manifests in young children. In this disease, the brain white matter is differentially affected in a predictable pattern with telencephalic brain areas being most severely affected, while ...
Jodie H.K. Man+7 more
doaj +1 more source
Metachromatic leukodystrophy and transplantation: remyelination, no cross‐correction
Objective In metachromatic leukodystrophy, a lysosomal storage disorder due to decreased arylsulfatase A activity, hematopoietic stem cell transplantation may stop brain demyelination and allow remyelination, thereby halting white matter degeneration ...
Nicole I. Wolf+15 more
doaj +1 more source
Ultra low-mass and small-radius white dwarfs made of heavy elements [PDF]
Seven ultra low-mass and small-radius white dwarfs (LSPM J0815+1633, LP 240-30, BD+20 5125B, LP 462-12, WD J1257+5428, 2MASS J13453297+4200437, and SDSS J085557.46+053524.5) have been recently identified with masses ranging from $\sim$0.02 $M_\odot$ to $\sim$0.08 $M_\odot$ and radii from $\sim$ 4270 km to 10670 km. The mass-radius measurements of these
arxiv +1 more source
White matter development in early puberty: a longitudinal volumetric and diffusion tensor imaging twin study. [PDF]
White matter microstructure and volume show synchronous developmental patterns in children. White matter volume increases considerably during development.
Rachel M Brouwer+8 more
doaj +1 more source
Association between Perivascular Spaces and Progression of White Matter Hyperintensities in Lacunar Stroke Patients. [PDF]
Perivascular spaces are associated with MRI markers of cerebral small vessel disease, including white matter hyperintensities. Although perivascular spaces are considered to be an early MRI marker of cerebral small vessel disease, it is unknown whether ...
Caroline M J Loos+3 more
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Constraining dark matter interactions mediated by a light scalar with white dwarfs [PDF]
Observations of white dwarfs in dark matter-rich environments can provide strong limits on the strength of dark matter interactions. Here we apply the recently improved formalism of the dark matter capture rate in white dwarfs to a general model in which dark matter interacts with the white dwarf ion components via a light scalar mediator.
arxiv +1 more source
Increased functional connectivity of white-matter in myotonic dystrophy type 1
BackgroundMyotonic dystrophy type 1 (DM1) is the most common and dominant inherited neuromuscular dystrophy disease in adults, involving multiple organs, including the brain.
Jing Li+21 more
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Background: The clinical significance of cerebral white matter hyperintensities (WMH) on brain magnetic resonance imaging (MRI) has recently increased, and recognized now as a risk factor for future stroke and dementia. High levels of plasma homocysteine
Kee Ook Lee+6 more
doaj +1 more source
Cerebral white matter disorders affecting behavior and cognition are reviewed from the University of Colorado School of Medicine, and Denver VA Medical Center.
J Gordon Millichap
doaj +1 more source
Spatial Coherence of Oriented White Matter Microstructure: Applications to White Matter Regions Associated with Genetic Similarity [PDF]
We present a method to discover differences between populations with respect to the spatial coherence of their oriented white matter microstructure in arbitrarily shaped white matter regions. This method is applied to diffusion MRI scans of a subset of the Human Connectome Project dataset: 57 pairs of monozygotic and 52 pairs of dizygotic twins.
arxiv +1 more source