Results 11 to 20 of about 3,224,961 (325)

Disconnected aging: cerebral white matter integrity and age-related differences in cognition. [PDF]

open access: yes, 2014
Cognition arises as a result of coordinated processing among distributed brain regions and disruptions to communication within these neural networks can result in cognitive dysfunction.
Bennett, IJ, Madden, DJ
core   +1 more source

Increased functional connectivity of white-matter in myotonic dystrophy type 1

open access: yesFrontiers in Neuroscience, 2022
BackgroundMyotonic dystrophy type 1 (DM1) is the most common and dominant inherited neuromuscular dystrophy disease in adults, involving multiple organs, including the brain.
Jing Li   +21 more
doaj   +1 more source

Differential Impact of Plasma Homocysteine Levels on the Periventricular and Subcortical White Matter Hyperintensities on the Brain

open access: yesFrontiers in Neurology, 2019
Background: The clinical significance of cerebral white matter hyperintensities (WMH) on brain magnetic resonance imaging (MRI) has recently increased, and recognized now as a risk factor for future stroke and dementia. High levels of plasma homocysteine
Kee Ook Lee   +6 more
doaj   +1 more source

Probing white-matter microstructure with higher-order diffusion tensors and susceptibility tensor MRI. [PDF]

open access: yes, 2013
Diffusion MRI has become an invaluable tool for studying white matter microstructure and brain connectivity. The emergence of quantitative susceptibility mapping and susceptibility tensor imaging (STI) has provided another unique tool for assessing the ...
Li, Wei, Liu, Chunlei, Murphy, Nicole E
core   +1 more source

Pretreatment cognitive and neural differences between sapropterin dihydrochloride responders and non-responders with phenylketonuria [PDF]

open access: yes, 2017
Sapropterin dihydrochloride (BH4) reduces phenylalanine (Phe) levels and improves white matter integrity in a subset of individuals with phenylketonuria (PKU) known as “responders.” Although prior research has identified biochemical and genotypic ...
Christ, Shawn E   +5 more
core   +4 more sources

White Matter Dementia

open access: yesPediatric Neurology Briefs, 1998
Cerebral white matter disorders affecting behavior and cognition are reviewed from the University of Colorado School of Medicine, and Denver VA Medical Center.
J Gordon Millichap
doaj   +1 more source

Isointense infant brain MRI segmentation with a dilated convolutional neural network [PDF]

open access: yes, 2017
Quantitative analysis of brain MRI at the age of 6 months is difficult because of the limited contrast between white matter and gray matter. In this study, we use a dilated triplanar convolutional neural network in combination with a non-dilated 3D ...
Moeskops, Pim, Pluim, Josien P. W.
core   +8 more sources

Rethinking the standard trans-cortical approaches in the light of superficial white matter anatomy

open access: yesNeural Regeneration Research, 2015
A better comprehension of the superficial white matter organization is important in order to minimize potential and avoidable damage to long or intermediate association fibre bundles during every step of a surgical approach.
Francesco Latini, Mats Ryttlefors
doaj   +1 more source

Intracranial electrophysiological and structural basis of BOLD functional connectivity in human brain white matter

open access: yesNature Communications, 2023
While functional MRI (fMRI) studies have mainly focused on gray matter, recent studies have consistently found that blood-oxygenation-level-dependent (BOLD) signals can be reliably detected in white matter, and functional connectivity (FC) has been ...
Yali Huang   +11 more
doaj   +1 more source

Modeling subcortical ischemic white matter injury in rodents: unmet need for a breakthrough in translational research

open access: yesNeural Regeneration Research, 2021
Subcortical ischemic white matter injury (SIWMI), pathological correlate of white matter hyperintensities or leukoaraiosis on magnetic resonance imaging, is a common cause of cognitive decline in elderly.
Yuexian Cui   +3 more
doaj   +1 more source

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