Results 21 to 30 of about 6,982,631 (374)

White Matter Dementia

open access: yesPediatric Neurology Briefs, 1998
Cerebral white matter disorders affecting behavior and cognition are reviewed from the University of Colorado School of Medicine, and Denver VA Medical Center.
J Gordon Millichap
doaj   +1 more source

White matter changes in Alzheimer’s disease: a focus on myelin and oligodendrocytes

open access: yesActa Neuropathologica Communications, 2018
Alzheimer’s disease (AD) is conceptualized as a progressive consequence of two hallmark pathological changes in grey matter: extracellular amyloid plaques and neurofibrillary tangles.
S. E. Nasrabady   +3 more
semanticscholar   +1 more source

Interleukin-6, age, and corpus callosum integrity. [PDF]

open access: yes, 2014
The contribution of inflammation to deleterious aging outcomes is increasingly recognized; however, little is known about the complex relationship between interleukin-6 (IL-6) and brain structure, or how this association might change with increasing age.
Bettcher, Brianne M   +13 more
core   +5 more sources

Rethinking the standard trans-cortical approaches in the light of superficial white matter anatomy

open access: yesNeural Regeneration Research, 2015
A better comprehension of the superficial white matter organization is important in order to minimize potential and avoidable damage to long or intermediate association fibre bundles during every step of a surgical approach.
Francesco Latini, Mats Ryttlefors
doaj   +1 more source

White matter hyperintensities: relationship to amyloid and tau burden.

open access: yesBrain : a journal of neurology, 2019
Although white matter hyperintensities have traditionally been viewed as a marker of vascular disease, recent pathology studies have found an association between white matter hyperintensities and Alzheimer's disease pathologies.
J. Graff‐Radford   +17 more
semanticscholar   +1 more source

Intracranial electrophysiological and structural basis of BOLD functional connectivity in human brain white matter

open access: yesNature Communications, 2023
While functional MRI (fMRI) studies have mainly focused on gray matter, recent studies have consistently found that blood-oxygenation-level-dependent (BOLD) signals can be reliably detected in white matter, and functional connectivity (FC) has been ...
Yali Huang   +11 more
doaj   +1 more source

Does functional MRI detect activation in white matter?A review of emerging evidence, issues, and future directions

open access: yesFrontiers in Neuroscience, 2014
Functional magnetic resonance imaging (fMRI) is a non-invasive technique that allows for visualization of activated brain regions. Until recently, fMRI studies have focused on gray matter.
Jodie Reanna Gawryluk   +2 more
doaj   +1 more source

Modeling subcortical ischemic white matter injury in rodents: unmet need for a breakthrough in translational research

open access: yesNeural Regeneration Research, 2021
Subcortical ischemic white matter injury (SIWMI), pathological correlate of white matter hyperintensities or leukoaraiosis on magnetic resonance imaging, is a common cause of cognitive decline in elderly.
Yuexian Cui   +3 more
doaj   +1 more source

Neuroinflammation and myelin status in Alzheimer’s disease, Parkinson’s disease, and normal aging brains: A small sample study [PDF]

open access: yes, 2019
Microglia and astrocytes play important roles in mediating the immune processes and nutritional support in the central nervous system (CNS). Neuroinflammation has been indicated in the progression of neurodegenerative diseases Alzheimer’s disease (AD ...
Benzinger, Tammie L. S.   +7 more
core   +2 more sources

Obsessive compulsive symptom dimensions are linked to altered white-matter microstructure in a community sample of youth

open access: yesTranslational Psychiatry, 2022
Obsessive-compulsive symptoms (OCS) are common in school-aged children and predict the development of obsessive compulsive disorder (OCD). White-matter abnormalities have been described in OCD, but the white matter correlates of OCS in the developing ...
Rachael G. Grazioplene   +4 more
doaj   +1 more source

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