Results 61 to 70 of about 5,567,921 (295)

Jacobi Hofschauspieler als Mephisto / [fotografiert von:] Gebrüder Matter [PDF]

, 1870
JACOBI HOFSCHAUSPIELER ALS MEPHISTO / [FOTOGRAFIERT VON:] GEBRÜDER MATTER [Künstlerfotografien zum Faustthema : Darsteller und Darstellerinnen des "Faust"] (-) Jacobi Hofschauspieler als Mephisto / [fotografiert von:] Gebrüder Matter (63) (1)
Matter
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Gray-white matter ratio in pediatric and adult cardiopulmonary arrest studies: a rapid review

Resuscitation Plus
Objectives: The gray-white matter ratio is used to estimate tissue edema on head computed tomography scans in cardiac arrest research. This rapid review aimed to determine whether gray-white matter ratio values differed between studies that included ...
Kie Honjo, Geraldine Goco, Ahmed Al Khalifah, Nicole McKinnon, Barnaby R. Scholefield, Suzanne Laughlin, Anne-Marie Guerguerian   +6 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Nonparenchymal fluid is the source of increased mean diffusivity in preclinical Alzheimer's disease

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2019
Introduction Although increased mean diffusivity of the white matter has been repeatedly linked to Alzheimer's disease pathology, the underlying mechanism is not known.
Farshid Sepehrband, Ryan P. Cabeen, Giuseppe Barisano, Nasim Sheikh‐Bahaei, Jeiran Choupan, Meng Law, Arthur W. Toga, Alzheimer's Disease Neuroimaging Initiative   +7 more
doaj   +1 more source

White matter matters: a multimodal approach to investigate white matter microstructure and metabolism

, 2014
White matter connects different brain areas and applies electrical insulation to the neuron’s axons with myelin sheaths in order to enable quick signal transmission.
Giezendanner, Stéphanie
core  

White matter tracts in first-episode psychosis: a DTI tractography study of the uncinate fasciculus. [PDF]

, 2008
A model of disconnectivity involving abnormalities in the cortex and connecting white matter pathways may explain the symptoms and cognitive abnormalities of schizophrenia.
Cercignani, M, Barnes, Thomas R.E., Ron, M A, Barnes, Thomas RE, Barnes, T R E, Parker, Geoffrey J M, Barnes, Thomas R E, Joyce, Eileen M, Altmann, Daniel R., Joyce, Eileen M., Ron, Maria A., Barker, Gareth J, Joyce, E M, Cercignani, Mara, Mara Cercignani (4463104), Parker, Geoffrey JM, Parker, G J M, Geoffrey J M Parker (16050170), Barker, Gareth J., Altmann, Daniel R, Barker, G J; id_orcid, Daniel R Altmann (7040552), Gareth J Barker (16050200), Maria A Ron (16050206), Eileen M Joyce (16050203), Thomas R E Barnes (16050197), Altmann, D R, Ron, Maria A, Gary Price (6445520), Price, G, Parker, Geoffrey J.M., Price, Gary   +31 more
core   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source