Results 61 to 70 of about 619,697 (299)

Calcified White Matter

Case Reports in Clinical Practice, 2018
No ...
Morteza Daraei
doaj  

Can white matter hyperintensities based Fazekas visual assessment scales inform about Alzheimer’s disease pathology in the population?

Alzheimer’s Research & Therapy
Background White matter hyperintensities (WMH) are considered hallmark features of cerebral small vessel disease and have recently been linked to Alzheimer’s disease (AD) pathology. Their distinct spatial distributions, namely periventricular versus deep
Aishwarya Pradeep, Sheelakumari Raghavan, Scott A. Przybelski, Gregory M. Preboske, Christopher G. Schwarz, Val J. Lowe, David S. Knopman, Ronald C. Petersen, Clifford R. Jack, Jonathan Graff-Radford, Petrice M. Cogswell, Prashanthi Vemuri   +11 more
doaj   +1 more source

White matter tracts in first-episode psychosis: a DTI tractography study of the uncinate fasciculus. [PDF]

, 2008
A model of disconnectivity involving abnormalities in the cortex and connecting white matter pathways may explain the symptoms and cognitive abnormalities of schizophrenia.
Cercignani, M, Barnes, Thomas R.E., Ron, M A, Barnes, Thomas RE, Barnes, T R E, Parker, Geoffrey J M, Barnes, Thomas R E, Joyce, Eileen M, Altmann, Daniel R., Joyce, Eileen M., Ron, Maria A., Barker, Gareth J, Joyce, E M, Cercignani, Mara, Mara Cercignani (4463104), Parker, Geoffrey JM, Parker, G J M, Geoffrey J M Parker (16050170), Barker, Gareth J., Altmann, Daniel R, Barker, G J; id_orcid, Daniel R Altmann (7040552), Gareth J Barker (16050200), Maria A Ron (16050206), Eileen M Joyce (16050203), Thomas R E Barnes (16050197), Altmann, D R, Ron, Maria A, Gary Price (6445520), Price, G, Parker, Geoffrey J.M., Price, Gary   +31 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Restricted Diffusion in Vanishing White Matter

, 2012
To investigate the occurrence of restricted diffusion in vanishing white matter, the affected structures,the time of occurrence in the disease course, and the histopathologic correlate. Retrospective observational study. Forty-six patients with vanishing
Steenweg, M.E., van der Knaap, M.S., van der Lei, Hannemieke D. W., van der Lei, H.D.W., van Wieringen, Wessel N., Bugiani, M., Barkhof, F., Pouwels, Petra J. W., van der Knaap, Marjo S., Vent, Inge M., van Wieringen, W.N., Pouwels, P.J.W., Vent, I.M., Bugiani, Marianna, Steenweg, Marjan E., Barkhof, Frederik, van Wieringen, W.N.; id_orcid   +16 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Gray-white matter ratio in pediatric and adult cardiopulmonary arrest studies: a rapid review

Resuscitation Plus
Objectives: The gray-white matter ratio is used to estimate tissue edema on head computed tomography scans in cardiac arrest research. This rapid review aimed to determine whether gray-white matter ratio values differed between studies that included ...
Kie Honjo, Geraldine Goco, Ahmed Al Khalifah, Nicole McKinnon, Barnaby R. Scholefield, Suzanne Laughlin, Anne-Marie Guerguerian   +6 more
doaj   +1 more source

Late onset vanishing white matter disease presenting with learning difficulties

, 2012
Background: Vanishing white matter is an inherited leukoencephalopathy with typical childhood onset. Late onset forms are rare and may present with an extended range of phenotypes.
van der Knaap, M.S., van der Lei, Hannemieke D. W., Ernestina Santos, van der Lei, H.D.W., Santos, Ernestina, Damásio, Joana, van der Knaap, Marjo S., Hannemieke D.W. van der Lei, Marjo S. van der Knaap, Santos, E., Joana Damásio, Damasio, J., Lei, H.D.W. van der, Knaap, M.S. van der   +13 more
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source