Results 81 to 90 of about 530,731 (253)

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Evaluation of brain white matter changes on MRI in patients newly diagnosed with obstructive sleep apnea compared with the control group

The Egyptian Journal of Bronchology
Background Obstructive sleep apnea (OSA) is nowadays introduced as a risk factor for white matter brain changes. Research on OSA and white matter changes provides contradictory evidence for the contextual link between the two conditions. This study aimed
Farzaneh Khoroushi, Yasmin Davoodi, Amirhossein Fathabadi, Reihane Bakhshi, Yasamin Sharifian, Maryam Salehi, Leila Ghofranyha, Ehsan Hassannejad, Farnaz Kharaghani   +8 more
doaj   +1 more source

Association between white matter hyperintensities and gray matter volume in cerebral small vessel disease: insights from periventricular and deep white matter lesions

Frontiers in Neurology
ObjectiveTo investigate the relationship between the severity of periventricular white matter hyperintensities (PWMH) and deep white matter hyperintensities (DWMH) and gray matter volume in cerebral small vessel disease (CSVD) patients.MethodsClinical ...
Weishun Feng, Xinjun Lei, Shida Xu, Zhihua Xu   +3 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Correspondence between white matter hyperintensities and regional grey matter volumes in Alzheimer's disease

Frontiers in Aging Neuroscience
ObjectiveWhite matter hyperintensities (WMH) are the most common neuroimaging manifestation of cerebral small vessel disease, and is frequently observed in Alzheimer’s disease (AD).
Fangyuan Yi, Fangyuan Yi, Jirui Wang, Meiqing Lin, Baizhu Li, Shiyu Han, Shan Wang, Yingbin Jin, Ning Hu, Yutong Chen, Xiuli Shang   +10 more
doaj   +1 more source

On the Trail of White Matter [PDF]

The Journal of Neuropsychiatry and Clinical Neurosciences, 2020
openaire   +2 more sources

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source

Research Progress on Tractography of Superficial White Matter Based on Diffusion Magnetic Resonance Imaging

Chinese Journal of Magnetic Resonance
In recent years, significant progress has been made in tractography of superficial white matter in the brain based on diffusion magnetic resonance imaging.
MENG Jingxin, WANG Yuanjun
doaj   +1 more source