Results 71 to 80 of about 5,567,921 (295)

Childhood Adversity and White Matter Microstructure: White Matter Differences Associated with Trauma Exposure

Stresses
Current research on the effects of childhood trauma largely focuses on maltreatment. In the current study, we used diffusion tensor imaging (DTI) to determine the association between potentially traumatic exposures not related to maltreatment and ...
Andrea Rodriguez, Helen Petropoulos, Pilar M. Sanjuan, Yu-Ping Wang, Tony W. Wilson, Vince D. Calhoun, Julia M. Stephen   +6 more
doaj   +1 more source

Influence of white matter inhomogeneous anisotropy on EEG forward computing [PDF]

, 2008
In this paper, we model the human head using the Volume and Wang’s constraint methods, and study the inhomogeneous anisotropic conductivity for white matter (WM) using finite element method (FEM).
Bashar, R., Wen, P., Li, Y.
core   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

FEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim, Thi Thanh Mai Tran, Nakyung Kang, Min‐Woo Lee, Mihye Lee   +4 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Multivariate prediction of white matter BOLD activity and its relationship to marginal connectivity

NeuroImage
Functional MRI studies have traditionally focused on gray matter, whereas white matter BOLD signals have often been treated as weak or artifactual.
Muwei Li, Zhaohua Ding, John C Gore
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Spatial coupling of enlarged perivascular spaces and white matter lesions across the Alzheimer's disease continuum

Frontiers in Neuroscience
IntroductionEmerging evidence suggests that impaired waste-clearance systems contribute to Alzheimer's disease pathogenesis, yet the etiology of clearance dysfunction markers, such as enlarged perivascular spaces, remains unclear.
Serena Tang, Serena Tang, Pamela Thropp, Isabella Hausle, Kyan Younes, Duygu Tosun, Duygu Tosun   +6 more
doaj   +1 more source

Compression analysis of the gray and white matter of the spinal cord

Neural Regeneration Research, 2020
The spinal cord is composed of gray matter and white matter. It is well known that the properties of these two tissues differ considerably. Spinal diseases often present with symptoms that are caused by spinal cord compression.
Norihiro Nishida, Fei Jiang, Junji Ohgi, Akihiro Tanaka, Yasuaki Imajo, Hidenori Suzuki, Masahiro Funaba, Takashi Sakai, Itsuo Sakuramoto, Xian Chen   +9 more
doaj   +1 more source

Extent of altered white matter in unilateral and bilateral periventricular white matter lesions in children with unilateral cerebral palsy

, 2016
Aims: To investigate the extent of white matter damage in children with unilateral cerebral palsy (UCP) caused by periventricular white matter lesions comparing between unilateral and bilateral lesions; and to investigate a relationship between white ...
Rose, S., Pannek, K., Boyd, Roslyn, Fiori, S., Scheck, S., Reid, L., Fripp, J., Fiori S, Rose SE, Scheck SM, Pannek K, Reid L, Boyd RN, Fripp J   +13 more
core   +1 more source

Different patterns of white matter degeneration using multiple diffusion indices and volumetric data in mild cognitive impairment and Alzheimer patients [PDF]

, 2012
Alzheimeŕs disease (AD) represents the most prevalent neurodegenerative disorder that causes cognitive decline in old age. In its early stages, AD is associated with microstructural abnormalities in white matter (WM).
Alves, Gilberto Sousa, Gilberto Sousa Alves, Felipe Sudo, Tarik Karakaya, Letice Valente, Laurence O’Dwyer, Viola Oertel-Knöchel, Engelhardt, Eliasz, David Prvulovic, Denise Moreira, Christian Knöchel, O’Dwyer, Laurence, Karakaya, Tarik, Fabian Fuβer, Carlos Eduardo Alves, Fußer, Fabian, Johannes Pantel, Laurence O'Dwyer, Valente, Letice, Jerson Laks, Prvulovic, David, Moreira, Denise, Alves, Carlos Eduardo, Alina Jurcoane, Pantel, Johannes, Oertel-Knöchel, Viola, Laks, Jerson, Eliasz Engelhardt, Sudo, Felipe, Fabian Fußer, Jurcoane, Alina, Knöchel, Christian, Alves Gilberto Sousa, Alves Carlos Eduardo, Prvulovic David, Sudo Felipe, Karakaya Tarik, Fuβer Fabian, Oertel-Knöchel Viola, O’Dwyer Laurence, Valente Letice, Moreira Denise, Knöchel Christian, Laks Jerson, Pantel Johannes, Engelhardt Eliasz, Jurcoane Alina   +46 more
core   +2 more sources