Results 11 to 20 of about 28,083 (302)

Independent and additive contribution of white matter hyperintensities and Alzheimer’s disease pathology to basal forebrain cholinergic system degeneration

open access: yesNeuroImage: Clinical, 2023
Objectives: Degeneration of the cholinergic basal forebrain nuclei (CBFN) system has been studied extensively in Alzheimer's disease (AD). White matter hyperintensities are a hallmark of aging as well as a common co-morbidity of AD, but their ...
Christine Kindler   +5 more
doaj   +1 more source

APOE4 carrier status determines association between white matter disease and grey matter atrophy in early-stage dementia

open access: yesAlzheimer’s Research & Therapy, 2023
Background White matter hyperintensities, a neuroimaging marker of small-vessel cerebrovascular disease and apolipoprotein ε4 (APOE4) allele, are important dementia risk factors.
Ashwati Vipin   +8 more
doaj   +1 more source

Association of Low Blood Pressure with White Matter Hyperintensities in Elderly Individuals with Controlled Hypertension [PDF]

open access: yesJournal of Stroke, 2020
Background and Purpose Both hypertension and hypotension increase cerebral white matter hyperintensities. However, the effects of hypotension in individuals with treated hypertension are unknown. We analyzed the association of low blood pressure with the
Jun Sung Kim   +8 more
doaj   +1 more source

Prevalence of white matter hyperintensities is not elevated in a large sample of adolescents and young adults with bipolar disorder [PDF]

open access: yesBrazilian Journal of Psychiatry, 2020
Objective: The increased prevalence rate of white matter hyperintensities is one of the most consistently reported brain abnormalities in adults with bipolar disorder.
Sara Z. Mehrhof   +7 more
doaj   +1 more source

Diabetes mellitus and white matter hyperintensity [PDF]

open access: yesGeriatrics & Gerontology International, 2015
White matter hyperintensity (WMH) is a brain lesion detected as a high‐intensity area in magnetic resonance imaging T2 and fluid‐attenuated inversion recovery images, and it has been suggested that WMH reflects damage to small vessels in periventricular and subcortical areas. Although WMH has been linked to the incidence of stroke, more recently it has
Yoshiaki, Tamura, Atsushi, Araki
openaire   +2 more sources

Modeling subcortical ischemic white matter injury in rodents: unmet need for a breakthrough in translational research

open access: yesNeural Regeneration Research, 2021
Subcortical ischemic white matter injury (SIWMI), pathological correlate of white matter hyperintensities or leukoaraiosis on magnetic resonance imaging, is a common cause of cognitive decline in elderly.
Yuexian Cui   +3 more
doaj   +1 more source

White Matter Hyperintensities and Medication Adherence [PDF]

open access: yesBiological Research For Nursing, 2008
White matter hyperintensities (WMH) are associated with hypertension, age, and cognitive function, but the association between WMH and medication adherence has not been examined. The intent of this investigation was to consider the potential implications of hypertension-related brain morphological changes on medication adherence and thereby improve ...
Kathleen C, Insel   +2 more
openaire   +2 more sources

Imprinting methylation predicts hippocampal volumes and hyperintensities and the change with age in later life

open access: yesScientific Reports, 2021
Epigenetic imprinting is important for neurogenesis and brain function. Hippocampal volumes and brain hyperintensities in late life have been associated with early life circumstances. Epigenetic imprinting may underpin these associations. Methylation was
Marlene Lorgen-Ritchie   +10 more
doaj   +1 more source

White matter hyperintensities and hypobaric exposure [PDF]

open access: yesAnnals of Neurology, 2014
ObjectiveDemonstrate that occupational exposure to nonhypoxic hypobaria is associated with subcortical white matter hyperintensities (WMHs) on fluid‐attenuated inversion recovery magnetic resonance imaging (MRI).MethodsEighty‐three altitude chamber personnel (PHY), 105 U‐2 pilots (U2P), and 148 age‐ controlled and health‐matched doctorate degree ...
Stephen A, McGuire   +7 more
openaire   +2 more sources

Relation between migraine pattern and white matter hyperintensities in brain magnetic resonance imaging

open access: yesThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2018
Background Migraine is a common disorder in general population. Presence of white matter hyperintensities (WMHs) in brain MRI of migraine patients was not studied clearly.
Mohamed Negm   +3 more
doaj   +1 more source

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