Results 31 to 40 of about 28,083 (302)

Validation of Automated White Matter Hyperintensity Segmentation [PDF]

Journal of Aging Research, 2011
Introduction. White matter hyperintensities (WMHs) are a common finding on MRI scans of older people and are associated with vascular disease. We compared 3 methods for automatically segmenting WMHs from MRI scans.Method. An operator manually segmented WMHs on MRI images from a 3T scanner.
Sean D. Smart, Michael J. Firbank, John T. O'Brien   +2 more
openaire   +3 more sources

Morphological Brain Changes after Climbing to Extreme Altitudes--A Prospective Cohort Study. [PDF]

PLoS ONE, 2015
Findings of cerebral cortical atrophy, white matter lesions and microhemorrhages have been reported in high-altitude climbers. The aim of this study was to evaluate structural cerebral changes in a large cohort of climbers after an ascent to extreme ...
Raimund Kottke, Jacqueline Pichler Hefti, Christian Rummel, Martinus Hauf, Urs Hefti, Tobias Michael Merz   +5 more
doaj   +1 more source

Late-life depression, heart failure and frontal white matter hyperintensity: a structural magnetic resonance imaging study

Brazilian Journal of Medical and Biological Research, 2005
The relevance of the relationship between cardiac disease and depressive symptoms is well established. White matter hyperintensity, a bright signal area in the brain on T2-weighted magnetic resonance imaging scans, has been separately associated with ...
J.R.C. Almeida, T.C.T.F. Alves, M. Wajngarten, J. Rays, C.C. Castro, Q. Cordeiro, R.M.S. Telles, R.J. Fraguas, G.F. Busatto   +8 more
doaj   +1 more source

Microstructural white matter changes preceding white matter hyperintensities in migraine

Neurology, 2019
We used magnetization transfer imaging to assess white matter tissue integrity in migraine, to explore whether white matter microstructure was more diffusely affected beyond visible white matter hyperintensities (WMHs), and to explore whether focal invisible microstructural changes precede visible focal WMHs in migraineurs.We included 137 migraineurs ...
Arkink, E.B., Palm-Meinders, I.H., Koppen, H., Milles, J., Lew, B. van, Launer, L.J., Hofman, P.A.M., Terwindt, G.M., Buchem, M.A. van, Ferrari, M.D., Kruit, M.C.   +10 more
openaire   +5 more sources

Migraine and white matter hyperintensities [PDF]

Neurology, 2013
OBJECTIVE: Migraine is associated with white matter hyperintensities (WMH) cross-sectionally, but its effect on WMH progression is uncertain. METHODS: Participants in the Atherosclerosis Risk in Communities cohort study (n = 10,924) completed a standardized headache questionnaire between 1993 and 1995.
Ali G, Hamedani, Kathryn M, Rose, B Lee, Peterlin, Thomas H, Mosley, Laura H, Coker, Clifford R, Jack, David S, Knopman, Alvaro, Alonso, Rebecca F, Gottesman   +8 more
openaire   +2 more sources

Cardiometabolic state links neurovascular burden with brain structure and function: Evidence from EEG and MRI

NeuroImage
Aging affects brain structure and function alongside metabolic and vascular processes leading to energetic impairments. While local neurometabolic dysfunction in aging is well-documented, the influence of systemic cardiometabolic and vascular markers on ...
Daniel Franco-O’Byrne, Ana M. Castro-Laguardia, Carolina Delgado, James M. Shine, David Huepe, Raul González-Gomez, Enzo Tagliazucchi, Cecilia Gonzalez-Campo, Agustín Ibañez, Vicente Medel   +9 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Early life socioeconomic circumstance and late life brain hyperintensities--a population based cohort study.

PLoS ONE, 2014
ContextThere have been many reports confirming the association between lower childhood socioeconomic circumstance and cardiovascular disease but evidence for links with cerebrovascular disease is contradictory.
Alison D Murray, Christopher J McNeil, Sima Salarirad, Lawrence J Whalley, Roger T Staff   +4 more
doaj   +1 more source

Pre-operative Cerebral Small Vessel Disease on MR Imaging Is Associated With Cerebral Hyperperfusion After Carotid Endarterectomy

Frontiers in Cardiovascular Medicine, 2021
Objectives: To determine whether pre-operative cerebral small vessel disease is associated with cerebral hyperperfusion (CH) after carotid endarterectomy (CEA).Methods: Seventy-seven patients (mean age of 66 years and 58% male) undergoing CEA for carotid
Xiaoyuan Fan, Zhichao Lai, Tianye Lin, Hui You, Juan Wei, Mingli Li, Changwei Liu, Feng Feng, Feng Feng   +8 more
doaj   +1 more source

White-matter hyperintensities in first-episode psychosis [PDF]

British Journal of Psychiatry, 2008
BackgroundWhite-matter hyperintensities have been associated with both schizophrenia and mood disorders, particularly bipolar disorder, but results are inconsistent across studiesAimsTo examine whether white-matter hyperintensities are a vulnerability marker for psychosis or are specifically associated with bipolar disorderMethodT2-weighted magnetic ...
Zanetti, Marcus V., Schaufelberger, Maristela S., de Castro, Cláudio C., Menezes, Paulo R., Scazufca, Márcia, McGuire, Philip K., Murray, Robin M., Busatto, Geraldo F.   +7 more
openaire   +2 more sources