Results 41 to 50 of about 1,170,509 (350)

Whole genome sequencing analysis of Plasmodium vivax using whole genome capture

BMC Genomics, 2012
Background Malaria caused by Plasmodium vivax is an experimentally neglected severe disease with a substantial burden on human health. Because of technical limitations, little is known about the biology of this important human pathogen.
Bright A, Tewhey Ryan, Abeles Shira, Chuquiyauri Raul, Llanos-Cuentas Alejandro, Ferreira Marcelo U, Schork Nicholas J, Vinetz Joseph M, Winzeler Elizabeth A   +8 more
doaj   +1 more source

Cronobacter, the emergent bacterial pathogen Enterobacter sakazakii comes of age; MLST and whole genome sequence analysis [PDF]

, 2014
Background: Following the association of Cronobacter spp. to several publicized fatal outbreaks in neonatal intensive care units of meningitis and necrotising enterocolitis, the World Health Organization (WHO) in 2004 requested the establishment of a ...
Dickins, B, Forsythe, SJ, Jolley, KA
core   +2 more sources

Salmonella Serotyping Using Whole Genome Sequencing

Frontiers in Microbiology, 2018
Until recently, traditional serology and the Kauffmann White Scheme (KWS) have been the gold standard for Salmonella serotyping. Whole Genome Sequencing (WGS) has now emerged as an alternative in this field.
George M. Ibrahim, Paul M. Morin
doaj   +1 more source

Toward 959 nematode genomes [PDF]

, 2012
The sequencing of the complete genome of the nematode Caenorhabditis elegans was a landmark achievement and ushered in a new era of whole-organism, systems analyses of the biology of this powerful model organism. The success of the C.
Blaxter, M, Kaur, G, Koutsovoulos, G, Kumar, S   +3 more
core   +1 more source

Rapid whole genome sequencing methods for RNA viruses

Frontiers in Microbiology, 2023
RNA viruses are the etiological agents of many infectious diseases. Since RNA viruses are error-prone during genome replication, rapid, accurate and economical whole RNA viral genome sequence determination is highly demanded.
Masayasu Misu, Masayasu Misu, Tomoki Yoshikawa, Satoko Sugimoto, Yuki Takamatsu, Takeshi Kurosu, Yukiteru Ouji, Masahide Yoshikawa, Masayuki Shimojima, Hideki Ebihara, Masayuki Saijo   +10 more
doaj   +1 more source

Performance of four modern whole genome amplification methods for copy number variant detection in single cells [PDF]

, 2017
Whole genome amplification (WGA) has become an invaluable tool to perform copy number variation (CNV) detection in single, or a limited number of cells.
Cornelis, Senne, Deforce, Dieter, Deleye, Lieselot, Tilleman, Laurentijn, Van Nieuwerburgh, Filip, Vander Plaetsen, Ann-Sophie   +5 more
core   +1 more source

Defining the oral microbiome by whole-genome sequencing and resistome analysis: the complexity of the healthy picture

BMC Microbiology, 2020
Background The microbiome of the oral cavity is the second-largest and diverse microbiota after the gut, harboring over 700 species of bacteria and including also fungi, viruses, and protozoa.
E. Caselli, C. Fabbri, M. D’Accolti, I. Soffritti, Cristian Bassi, S. Mazzacane, Maurizio Franchi   +6 more
semanticscholar   +1 more source

The challenge of consent in clinical genome-wide testing [PDF]

, 2016
Genome-wide testing methods include array comparative genomic hybridisation (aCGH), multiple gene panels, whole exome sequencing (WE) and whole genome sequencing (WGS).
Burke, Katherine, Clarke, Angus
core   +1 more source

A beginner's guide to low‐coverage whole genome sequencing for population genomics

Molecular Ecology, 2020
Low‐coverage whole genome sequencing (lcWGS) has emerged as a powerful and cost‐effective approach for population genomic studies in both model and nonmodel species.
R. Lou, A. Jacobs, Aryn P. Wilder, N. Therkildsen   +3 more
semanticscholar   +1 more source

Clonal evolution in relapsed acute myeloid leukemia revealed by whole genome sequencing

Nature, 2011
Most patients with acute myeloid leukaemia (AML) die from progressive disease after relapse, which is associated with clonal evolution at the cytogenetic level. To determine the mutational spectrum associated with relapse, we sequenced the primary tumour
L. Ding, T. Ley, D. Larson, Christopher A. Miller, D. Koboldt, J. Welch, Julie Ritchey, Margaret A. Young, T. Lamprecht, M. McLellan, Joshua F. McMichael, J. Wallis, Charles Lu, D. Shen, C. Harris, D. Dooling, R. Fulton, L. Fulton, Ken Chen, Heather K. Schmidt, Joelle M. Kalicki-Veizer, V. Magrini, L. Cook, S. McGrath, T. Vickery, M. Wendl, S. Heath, M. Watson, D. Link, M. Tomasson, W. Shannon, J. Payton, S. Kulkarni, P. Westervelt, M. Walter, T. Graubert, E. Mardis, R. Wilson, J. Dipersio   +38 more
semanticscholar   +1 more source