Results 151 to 160 of about 168,253 (297)

Assessment of the molecular mechanisms of drug‐induced hidden cardiotoxicity by a multi‐omics approach: The example of rofecoxib

British Journal of Pharmacology, EarlyView.
Background and Purpose Hidden cardiotoxicity is defined as drug‐induced cardiotoxicity that becomes obvious only in the presence of comorbidities. However, the molecular mechanisms of hidden cardiotoxicity are not always known. Therefore, unbiased multi‐omics approaches could assist in revealing regulatory pathways.
Bennet Y. Weber, Gábor B. Brenner, Barnabás Váradi, Bence Ágg, Csenger Kovácsházi, Olivér M. Balogh, Donagh Egan, Kieran Wynne, David Matallanas, Rainer Schulz, Péter Ferdinandy, Zoltán Giricz, Anikó Görbe   +12 more
wiley   +1 more source

Effect of Frequency of Prospekta Administration: Anxiolytic Effect in Wistar Rats. [PDF]

Dose Response
Svitkin K, Morozova E, Krasheninnikova A, Kardash E, Ganina K, Emelyanova A, Tarasov S, Epstein O.   +7 more
europepmc   +1 more source

Circulatory Effects of the Prostaglandin E₁ on Spontaneously Hypertensive Rats and Normotensive Wistar Rats

, 1976
Masahiko KOGURE, Nagao Kajiwara, Masayuki Koshino, Takashi Sasaki, Gentaro Takahashi, Minoru Kubota, Akio Yamamura, Muneaki Furukata, Kazuaki Kuroda, K Sakai, Michinobu Hatano   +10 more
openalex   +2 more sources

The Application of Polymeric Nanoparticles as Drug Delivery Carriers to Cells in Neurodegenerative Diseases

Cell Proliferation, EarlyView.
Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin, Libo Nie, Yan Deng, Ghulam Jilany Khana, Nongyue He   +4 more
wiley   +1 more source

In Vitro Fertilization of Rat Eggs with Special Reference to Temporal Relationship between Penetration and Development of Sperm Head in the Rats of Wistar Strain

, 1978
Masashi Miyake, Koji Niwa, A. Iritani
openalex   +2 more sources

Exercise Delays Brain Ageing Through Muscle‐Brain Crosstalk

Cell Proliferation, EarlyView.
This graphical abstract illustrates the reciprocal crosstalk between the brain and peripheral organs, highlighting the profound impact of exercise on brain health through systemic interactions. It underscores how exercise influences the brain via signals from various organs and, conversely, how the brain modulates functions of peripheral organs.
Shirin Pourteymour, Rakesh Kumar Majhi, Frode A. Norheim, Christian A. Drevon   +3 more
wiley   +1 more source

Non-Celiac Wheat Gluten Sensitivity Model: Effects on Hepatic Morphophysiology of Wistar Rats. [PDF]

Nutrients
Duarte ALR, Silva GBVD, Santa Rosa AC, Raniero GZ, Monteiro ARG, de Souza GH, Sá-Nakanishi AB, Comar JF, Cuman RKN, Natali MRM.   +9 more
europepmc   +1 more source

TOXIC EFFECTS OF CYCLOSPORINE ON THE ENDOCRINE PANCREAS OF WISTAR RATS

, 1986
Hans-Jürgen Hahn, F. Laube, S Lücke, Ingrid Klöting, К.-D. Kohnert, R. WARZOCK   +5 more
openalex   +1 more source

Accelerating Bone Healing With METTL3 Overexpressed Adipose‐Derived Stem Cells in Osteoporotic Rats

Cell Proliferation, EarlyView.
METTL3 promotes osteogenic differentiation of osteoporotic adipose‐derived stem cells and accelerates the repair of cranial defect areas in osteoporotic rats by activating the Wnt signalling pathway. ABSTRACT The treatment of postmenopausal osteoporosis (OP) presents a multifaceted challenge.
Hui Tang, Zhenzhen Chen, Lu Zeng, Yuping Xie, Daowen Luo, Shuanglin Peng, Fangzhi Lou, Tianli Wu, Jingang Xiao   +8 more
wiley   +1 more source

Chromolaena Odorata and male fertility: Evidence from the testes and epididymis of Wistar Rats. [PDF]

Reprod Fertil
Uwejigho RE, Enemali F, Emojevwe V, Jesuyomike OM, Adeyomoye OI.   +4 more
europepmc   +1 more source