Results 71 to 80 of about 114,628,411 (160)
Scientific ReportsWith the aging process of the global population and the development of medical technology, the cases of postoperative cognitive dysfunction (POCD) are also increasing.
Haijun Hu +7 more
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Molecular Mechanism behind the Safe Immunostimulatory Effect of Withania somnifera
Biomolecules, 2023 Withania somnifera (L.) Dunal (family Solanaceae) is a medicinal plant known for, among many pharmacological properties, an immune boosting effect. Our recent study revealed that its key immunostimulatory factor is lipopolysaccharide of plant-associated ...
Kriti Kalpana +3 more
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British Journal of Pharmacology, EarlyView.Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka +3 more
wiley +1 more source
Rapid and sensitive method for determination of withaferin-A in human plasma by HPLC
, 2011 Background: To develop and validate a rapid and sensitive high-performance liquid chromatographic method for determination of withaferin-A in human plasma.
Pankaj Patial, Vikram Gota
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Nano Select, Volume 7, Issue 10, October 2026.Surface‐modified niosomes are introduced as multifunctional nanoparticles for precision tumor treatment that combine hydrophilic and lipophilic drug encapsulation with ligand‐based targeting via antibodies, peptides, transferrin, and folic acid. This modification leads to increased tumor selectivity, facilitates cell entry, and enables enhanced ...
Narges Sahraei +3 more
wiley +1 more source
Nanoencapsulation of Withaferin-A for the Treatment of Neurological Disorder [PDF]
, 2022 A better delivery mechanism is ensured by a superior formulation. This study is based on the fact that people believe in natural products more than chemical products.
Sonu Sharma, Dr. Viney Lather, Dr. Vikram Sharma
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Genetic and Withaferin A Analysis of Iranian Natural Populations of and by RAPD and HPTLC
Natural Product Communications, 2009 For successful conservation and breeding of a medicinal species, it is important to evaluate its genetic diversity as well as its content of phytochemical compounds. The aim of the present study was to investigate the genetic variation of Iranian natural
Mohammad Hossein Mirjalili +4 more
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The FASEB Journal, Volume 40, Issue 18, 30 September 2026.MR identified phenylalanine as a causal PC risk factor (OR 1.18). A 5‐gene RF model (AUC 0.955) highlighted SLC6A14 as the top biomarker. Single‐cell analysis revealed epithelial–immune crosstalk. Molecular docking identified genistein (−9.1 kcal/mol) as a lead SLC6A14‐targeting compound.
Xing Liu +3 more
wiley +1 more source
Withaferin A promotes proliferation and migration of brain endothelial cells [PDF]
, 2016 Purpose: To investigate the effect of withaferin A (WFA) on the proliferation and migration of brain endothelial cells.Methods: BALB-5023 mouse microvascular cells were treated with a range of withaferin A (WFA) concentrations from 10 to 100 ng/mL ...
Huang, Li-An +3 more
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MedComm, Volume 7, Issue 9, September 2026.Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan +9 more
wiley +1 more source