Results 121 to 130 of about 102,615,988 (206)

Ring A structural modified derivatives of withaferin A and the evaluation of their cytotoxic potential

, 2011
Regio-/stereoselective Michael addition to ring A of withaferin-A was performed using an optimized reaction procedure to synthesise a library of 2,3-dihydro,3- -substituted withaferin-A derivatives. The analogues thus obtained were evaluated for in vitro
Debaraj Mukherjee, Saxsena, A.K., Rabiya Majeed, Yousuf, Syed Khalid, Syed Khalid Yousuf, Majeed, Rabiya, Purnima, Basant, K.A. Suri, Sangwan, Payare lal, Payare lal Sangwan, Ahmad, Mudassier, Taneja, Subhash Chandra, Suri, K.A., Mukherjee, Debaraj, Mudassier Ahmad, A.K. Saxsena, Basant Purnima, Subhash Chandra Taneja   +17 more
core   +1 more source

Withaferin a suppresses the expression of vascular endothelial growth factor in ehrlich ascites tumor cells via sp1 transcription factor

, 2009
In the ayurvedic system of medicine, the medicinal plant, Withania somnifera Dunal (Solanaceae) finds application for numerous ailments including cancer.
Bharathi P. Salimath, Prasanna Kumar, S., Shilpa, P.   +2 more
core  

Protective effect of Withaferin-A on tumour formation in 7,12-dimethylbenz[a]anthracene induced oral carcinogenesis in hamsters

, 2009
16-23With an aim to investigate the protective effect of Withaferin-A on 7,12-dimethylbenz[a]anthracene (DMBA) induced oral carcinogenesis in Syrian golden hamsters, tumour incidence, tumour volume and tumour burden and status of detoxication agents ...
Manoharan, S, Alias, Linsa Mary, Menon, Venugopal P, Balakrishnan, S, Panjamurthy, K   +4 more
core  

Combinatorial phenethyl isothiocyanate and withaferin A targets multiple epigenetics pathways to inhibit MCF-7 and MDA-MB-231 human breast cancer cells

Cancer Cell International
Background Epigenetic phytochemicals are considered as an efficacious and safe alternative to synthetic drugs in drug discovery. In this regard, combinatorial interventions enable simultaneously targeting various neoplastic pathways to eradicate multiple
Mohammad Mijanur Rahman, Trygve O. Tollefsbol   +1 more
doaj   +1 more source

Withanolides Are Detected in Human Urine Following Oral Administration of a <i>Withania somnifera</i> Product. [PDF]

Int J Mol Sci
Speers AB, Limoico ED, Lozano-Ortiz A, Marney L, Choi J, Barr SA, Williamson RT, Strangman WK, Maier CS, Soumyanath A.   +9 more
europepmc   +1 more source

Nutraceutical Applications of <i>Withania somnifera</i>: The Scientific Knowledge for Rational Modern Use of the "Ayurvedic Adaptogen". [PDF]

Foods
Pandey S, Pant P, Corbioli G, Bonazzi E, Cisneros-Yupanqui M, Salmaso P, Dall'Acqua S.   +6 more
europepmc   +1 more source

Combined Effects of Withaferin A and Sodium Butyrate on NF-κB Signaling and Epigenetic Regulation in Breast Cancer Cells. [PDF]

Nutrients
Witt BL, Singaravelan N, Tollefsbol TO.
europepmc   +1 more source

New Vistas for Withania somnifera in Signal Transduction of Inflammation and Aging. [PDF]

Pharm Res
Sharma E, Mehta D, Muthuraj P, Panda S, Ajgaonkar S, Maniar D, Biju A, Nair S.   +7 more
europepmc   +1 more source

Molecular docking analysis of DprE1 from <i>M. tuberculosis</i> with phytochemicals. [PDF]

Bioinformation
Raja J, Blessy JJ.
europepmc   +1 more source

Withaferin A, a candidate drug for lupus nephritis, confers renal protection via Pon1‑mediated attenuation of oxidative stress. [PDF]

Int J Mol Med
Xue M, Feng J, Mao X.
europepmc   +1 more source