Results 51 to 60 of about 113,931,576 (202)

Benefits of Withania somnifera (Ashwagandha) supplementation in obesity

Journal of Education, Health and Sport, 2023
Introduction and purpose: Ashwagandha (fam. Solanaceae) also known as Withania somnifera, is an herb commonly used in traditional Ayurvedic medicine. It is sometimes called Indian ginseng or winter cherry and it is used for its extensive health benefits
Alicja Nowak, Klaudia Bogusz, Natalia Baran, Marcela Maksymowicz, Adriana Bielak, Aleksandra Nowak, Łucja Cywka, Weronika Szwed, Piotr Machowiec   +8 more
doaj   +1 more source

Estimating the production of withaferin A and withanolide A in Withania somnifera (L.) dunal using aquaponics for sustainable development in hill agriculture

Frontiers in Plant Science, 2023
IntroductionHumanity is suffering from huge and severe difficulties, including changes in climate, soil degradation, scarcity of water and the security of food and medicines, among others.
Manali Singh, Shivani Bhutani, Nisha Dinkar, Anita Mishra, Kahkashan Perveen, Alanoud T. Alfagham, Mehrun Nisha Khanam, Santosh Chandra Bhatt, Deep Chandra Suyal   +8 more
doaj   +1 more source

Evaluation of the Cytotoxic, Anti-Inflammatory, and Immunomodulatory Effects of Withaferin A (WA) against Lipopolysaccharide (LPS)-Induced Inflammation in Immune Cells Derived from BALB/c Mice

Pharmaceutics, 2022
(1) Background: Inflammation is one of the primary responses of the immune system and plays a key role in the pathophysiology of various diseases. Recent reports suggest that various phytochemicals exhibit promising anti-inflammatory and immunomodulation
Abdullah M. Alnuqaydan, Abdulmajeed Almutary, Gh Rasool Bhat, Tanveer Ahmad Mir, Shadil Ibrahim Wani, Mohd Younis Rather, Shabir Ahmad Mir, Bader Alshehri, Sulaiman Alnasser, Faten M. Ali Zainy, Bilal Rah   +10 more
doaj   +1 more source

Withaferin A for COVID-19: a Network Pharmacology Approach

Applied Biochemistry and Biotechnology, 2023
COVID-19 has become a global challenge as there are very few treatment options available. This has proved to impact several physiological implications like immunological injury, myocardial infarction, micro-thrombus formation, neurological complications and multi-organ dysfunction. A combination therapy or a systems pharmacology approach can be adopted
Ashasmita S. Mishra, Bhuvaneswari Varadarajan, Srayaa Sathish, Sujata Roy   +3 more
openaire   +2 more sources

Withaferin A recovery in sWRE.

, 2013
sWRE powder was dissolved in different solvents and the concentration (A) and recovery rate (B) of Withaferin A in sWRE was measured by HPLC. The stability of Withaferin A in sWRE (90% EtOH stock solution) over time is shown in a bar graph with the ...
Doris R. Powell (457630), Songli Xu (457629), Anapatricia Garcia (457628), Paula M. Vertino (457631), Zhen Yang (107412), Adam I. Marcus (457633), Shivendra Singh (457632)   +6 more
core   +1 more source

ISOLATION AND CHARACTERIZATION OF WITHAFERIN-A FROM THE WITHANIA SOMNIFERA (ASHWAGANDHA) [PDF]

, 2017
The research work is related to an improved process of isolation & characterization of Withaferin-A from withania somnifera (Sanskrit: Ashawagandha, English: Winter cherry).
Rakesh Kumar Jat, Bali Reddy Keesara, Keesara, Bali Reddy, Jat, Rakesh Kumar   +3 more
core   +1 more source

Pharmacokinetics and bioequivalence of Withania somnifera (Ashwagandha) extracts – A double blind, crossover study in healthy adults

Heliyon, 2023
Introduction: Withania somnifera (WS) or ashwagandha is an adaptogenic plant used extensively in traditional medicines and as a food supplement. Despite a long history of use and numerous clinical trials, the human pharmacokinetics of withanolides, the ...
Se-Kwon Kim, Jayachandran Venkatesan, Priyank Rathi, Benny Antony   +3 more
doaj   +1 more source

Withaferin A Analogs That Target the AAA+ Chaperone p97 [PDF]

ACS Chemical Biology, 2015
Understanding the mode of action (MOA) of many natural products can be puzzling with mechanistic clues that seem to lack a common thread. One such puzzle lies in the evaluation of the antitumor properties of the natural product withaferin A (WFA). A variety of seemingly unrelated pathways have been identified to explain its activity, suggesting a lack ...
Shasha, Tao, Joseph, Tillotson, E M Kithsiri, Wijeratne, Ya-Ming, Xu, MinJin, Kang, Tongde, Wu, Eric C, Lau, Celestina, Mesa, Damian J, Mason, Robert V, Brown, James J La, Clair, A A Leslie, Gunatilaka, Donna D, Zhang, Eli, Chapman   +13 more
openaire   +2 more sources

Enhanced production of withaferin - a in shoot cultures of Withania somnifera (L) Dunal [PDF]

, 2014
Withania somnifera (L) Dunal, commonly known as ashwagandha or Indian ginseng, is the source of large number of pharmacologically active withanolides. Withaferin-A (WS-3), a major withanolide of W.
Koul, Sushma, Khazir, Jabeena, Cowan, Don A., Hakeem, Khalid Rehman, Mir, Bilal Ahmad, Hakeem, Khalid R.   +5 more
core   +1 more source

Design and synthesis of new withaferin A inspired hedgehog pathway inhibitors [PDF]

, 2021
Withanolides constitute a well-known family of plant-based alkaloids characterised by widespread biological properties, including the ability of interfering with Hedgehog (Hh) signalling pathway.
Basili I., Passarella D., Mori M., Bonandi E., Calcaterra A., Botta B., Infante P., Catti F., Di Marcotullio L.   +8 more
core   +1 more source