Results 81 to 90 of about 113,931,576 (202)
Rapid and sensitive method for determination of withaferin-A in human plasma by HPLC
, 2011 Background: To develop and validate a rapid and sensitive high-performance liquid chromatographic method for determination of withaferin-A in human plasma.
Pankaj Patial, Vikram Gota
core +1 more source
The FASEB Journal, Volume 40, Issue 18, 30 September 2026.MR identified phenylalanine as a causal PC risk factor (OR 1.18). A 5‐gene RF model (AUC 0.955) highlighted SLC6A14 as the top biomarker. Single‐cell analysis revealed epithelial–immune crosstalk. Molecular docking identified genistein (−9.1 kcal/mol) as a lead SLC6A14‐targeting compound.
Xing Liu +3 more
wiley +1 more source
Broad-spectrum antitumor properties of Withaferin A: a proteomic perspective
RSC Medicinal Chemistry, 2020 A review discussing the broad-spectrum antitumor properties of the natural steroid Withaferin A based on the binding with its true cancer protein targets: a defined stress dependent and stress independent mode of action.
Martin Dom +2 more
openaire +4 more sources
MedComm, Volume 7, Issue 9, September 2026.Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan +9 more
wiley +1 more source
Withaferin A attenuates ovalbumin induced airway inflammation
Frontiers in Bioscience, 2019 The molecular mechanism of how airway inflammation develops is not fully understood. Withaferin A (WA) is a natural phytochemical isolated from the plant Withania somnifera. It is a well-investigated bioactive compound that possesses a variety of health-promoting effects, including anti-inflammatory and anti-oxidative activities.
Hong Mei, Zhao +4 more
openaire +2 more sources
Ferroptosis: Newly Emerged Regulator for Human Disease
MedComm, Volume 7, Issue 9, September 2026.Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao +4 more
wiley +1 more source
Nanoencapsulation of Withaferin-A for the Treatment of Neurological Disorder [PDF]
, 2022 A better delivery mechanism is ensured by a superior formulation. This study is based on the fact that people believe in natural products more than chemical products.
Sonu Sharma, Dr. Viney Lather, Dr. Vikram Sharma
core +1 more source
MedComm – Oncology, Volume 5, Issue 3, September 2026.Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K +5 more
wiley +1 more source
Genetic and Withaferin A Analysis of Iranian Natural Populations of and by RAPD and HPTLC
Natural Product Communications, 2009 For successful conservation and breeding of a medicinal species, it is important to evaluate its genetic diversity as well as its content of phytochemical compounds. The aim of the present study was to investigate the genetic variation of Iranian natural
Mohammad Hossein Mirjalili +4 more
doaj +1 more source
Withaferin A promotes proliferation and migration of brain endothelial cells [PDF]
, 2016 Purpose: To investigate the effect of withaferin A (WFA) on the proliferation and migration of brain endothelial cells.Methods: BALB-5023 mouse microvascular cells were treated with a range of withaferin A (WFA) concentrations from 10 to 100 ng/mL ...
Huang, Li-An +3 more
core +1 more source