Results 91 to 100 of about 118,549,391 (165)
eFood, Volume 7, Issue 4, August 2026.Physapubescin B may interfere with multiple cancer‐associated signaling pathways by inhibiting Ras/Raf/mitogen‐activated protein kinase kinase/extracellular signal‐regulated kinase (Ras/Raf/MEK/ERK) signaling and vascular endothelial growth factor (VEGF)‐dependent angiogenesis.
Wojciech Koch +11 more
wiley +1 more source
, 2013 The hydrogen bond interactions between the p21WAF1 (PDB-id: 1AXC) and small molecules - withaferin A and withanone.
M. Uthayakumar (308967) +9 more
core +1 more source
Withaferin A Suppresses Liver Tumor Growth in a Nude Mouse Model by Downregulation of Cell Signaling Pathway Leading to Invasion and Angiogenesis [PDF]
, 2015 Purpose: To investigate the effect of withaferin A on tumor growth and metastasis in liver in a nude mouse model.Methods: Withaferin A was injected through a portal vein to the orthotopic liver tumor in a nude mice model.
Wang, YX, Dong, CW, Ding, WB
core +1 more source
, 2021 © 2021, The Author(s), under exclusive licence to Springer Nature B.V. part of Springer Nature.Abnormal expression of claudin-1 (CLDN1) has important roles in carcinogenesis and metastasis in various cancers. The role of CLDN1 in human oral squamous cell
Swarup, Neeti +29 more
core +1 more source
Withaferin A Associated Differential Regulation of Inflammatory Cytokines
Frontiers in Immunology, 2018 A role of inflammation-associated cytokines/chemokines has been implicated in a wide variety of human diseases. Here, we investigated the regulation of inflammatory cytokines released by monocyte-derived THP-1 cells following treatment with the dietary ...
Seema Dubey +5 more
doaj +1 more source
Withaferin-A: A Potential Anticancer Withanolide from \u3cem\u3eWithania somnifera\u3c/em\u3e (L.) Dun. [PDF]
, 2005 Withania somnifera (Ashwagandha) is a plant used in medicine from the time of Ayurveda, the ancient system of Indian medicine. The dried roots of the plant are used in the treatment of nervous and sexual disorders.
Singh, Amrit Pal
core
Scientific ReportsEnterovirus D68 (EV-D68) is a significant global health threat, responsible for severe respiratory and neurological complications, with no FDA-approved antiviral treatments currently available.
Mansoor Alsahag
doaj +1 more source
Molecular Cancer, 2010 Background Multidrug resistance (MDR) is a major obstacle in cancer treatment and is often the result of overexpression of the drug efflux protein, P-glycoprotein (P-gp), as a consequence of hyperactivation of NFκB, AP1 and Nrf2 transcription factors. In
Gerlo Sarah +7 more
doaj +1 more source
, 2013 The hydrogen bond interactions between the NRF-2 (PDB-id: 2FLU) and small molecules - withaferin A and withanone.
M. Uthayakumar (308967) +9 more
core +1 more source
NRF2, a target of withanone and withaferin A.
, 2013 Docking of withanone (Wi-N) (A) and withaferin A (Wi-A) (B) with Nrf-2 (PDB-id: 2FLU), and Western blot analysis of Nrf2 in U2OS cells treated with Wi-A and Wi-N (C). (D) Detection of Nrf2 in the nuclear and cytosolic fractions of cells treated with Wi-A
M. Uthayakumar (308967) +9 more
core +1 more source