Results 81 to 90 of about 3,275 (173)

Pharmacological induction of acetyl-CoA carboxylase 1 autophagic degradation attenuates lipid accumulation and cholangiocarcinoma progression

Journal of Experimental & Clinical Cancer Research
Background Aberrant glycogen metabolism drives lipid accumulation and adaptive lipid homeostasis reprogramming, a metabolic adaptation critical for sustaining malignant progression and chemoresistance in cholangiocarcinoma (CCA).
Yani Pan, Nannan Zhang, Xueni Fu, Xinyu Wang, Yichun Ma, Qi Chen, Yue Zhou, Hongwen Liu, Yun Zhu, Lei Xu, Qiang Wang, Dongyin Chen, Zhangding Wang, Lei Wang   +13 more
doaj   +1 more source

Combinatorial phenethyl isothiocyanate and withaferin A targets multiple epigenetics pathways to inhibit MCF-7 and MDA-MB-231 human breast cancer cells

Cancer Cell International
Background Epigenetic phytochemicals are considered as an efficacious and safe alternative to synthetic drugs in drug discovery. In this regard, combinatorial interventions enable simultaneously targeting various neoplastic pathways to eradicate multiple
Mohammad Mijanur Rahman, Trygve O. Tollefsbol   +1 more
doaj   +1 more source

New Vistas for Withania somnifera in Signal Transduction of Inflammation and Aging. [PDF]

Pharm Res
Sharma E, Mehta D, Muthuraj P, Panda S, Ajgaonkar S, Maniar D, Biju A, Nair S.   +7 more
europepmc   +1 more source

Combined Effects of Withaferin A and Sodium Butyrate on NF-κB Signaling and Epigenetic Regulation in Breast Cancer Cells. [PDF]

Nutrients
Witt BL, Singaravelan N, Tollefsbol TO.
europepmc   +1 more source

Molecular docking analysis of DprE1 from <i>M. tuberculosis</i> with phytochemicals. [PDF]

Bioinformation
Raja J, Blessy JJ.
europepmc   +1 more source

Withaferin A, a candidate drug for lupus nephritis, confers renal protection via Pon1‑mediated attenuation of oxidative stress. [PDF]

Int J Mol Med
Xue M, Feng J, Mao X.
europepmc   +1 more source

DFT supported computational insights into Withaferin A structure and its binding interaction with Hsp90. [PDF]

Sci Rep
Shoni R, Karki PR, Tripathi K.
europepmc   +1 more source

Oral Administration of Withaferin A Increases Infiltration of CD4⁺ Helper T Cells in a Mouse Model of Mammary Tumor. [PDF]

J Cancer Prev
Hahm ER, Singh KB, Singh SV.
europepmc   +1 more source

Ashwagandha (Withania Somnifera): a comprehensive narrative review of its role in enhancing physical performance and health. [PDF]

Nutr Metab (Lond)
Nobari H, Parnian-Khajehdizaj N, Johnson K, Ramos-Álvarez JJ.   +3 more
europepmc   +1 more source

RETRACTION: Proinflammatory Cytokines IL-6 and TNF-α Increased Telomerase Activity through NF-κB/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells. [PDF]

Mediators Inflamm
Inflammation MO.
europepmc   +1 more source