Results 161 to 170 of about 2,412 (209)

Trypanocidal Withanolides and Withanolide Glycosides from Dunalia brachyacantha

Journal of Natural Products, 2001
Two new withanolide glycosides, (20R,22R)-O-(3)-alpha-L-rhamnopyranosyl(1-->4)-beta-D-glucopyranosyl-1 alpha,12 beta-diacetoxy-20-hydroxywitha-5,24-dienolide (3) and (20R,22R)-O-(3)-beta-D-xylopyranosyl(1-->3)-[beta-D-xylopyranosyl(1-->4)]-beta-D-glucopyranosyl-1 alpha-acetoxy-12 beta,20-dihydroxywitha-5,24-dienolide (4), were isolated from the leaves ...
J A, Bravo B, M, Sauvain, A, Gimenez T, E, Balanza, L, Serani, O, Laprévote, G, Massiot, C, Lavaud   +7 more
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Withanolide C, A chlorinated withanolide from Withania somnifera

Phytochemistry, 1992
Abstract The structure of a new chlorinated withanolide isolated from Withania somnifera chemotype III has been elucidated as 5α-chloro,6β,14α,17β,2Oα F -tetrahydroxy-l-oxo-22R-witha-2,24-dienolide by 1 H and 13 CNMR and chemical ionization mass spectroscopy methods.
Roberto Bessalle, David Lavie
openaire   +1 more source

Withanolide Y, a withanolide from a hybrid of Withania somnifera

Phytochemistry, 1987
Abstract The structure of a withanolide isolated from the hybrid of Withania somnifera chemotype III (Israel) by Indian I (Delhi) has been elucidated as (20R,22R)-5α,6α-epoxy-7α-17α,20-trihydroxy-1-oxo-witha-2,24-dienolide by X-ray single crystal analysis.
Roberto Bessalle, David Lavie, Felix Frolow   +2 more
openaire   +1 more source

Natural Bioactive New Withanolides

Mini-Reviews in Medicinal Chemistry, 2020
Withanolides are a group of highly oxygenated steroids derived from a C28 ergostane skeleton, and have attracted significant scientific interest due to their complex structural features and multiple bioactivities. More than 170 new natural withanolides were isolated and identified in the last 5 years.
Qian-Qian, Xu, Kui-Wu, Wang
openaire   +2 more sources

Withanolides from Iochroma gesnerioides

Phytochemistry, 1994
Three new acetylated withanolides, two of which are diacetylated, were isolated from the aerial parts of Iochroma gesnerioides. Furthermore, six methoxylated derivatives were identified, but they are considered to be artefacts produced during the ...
Dorothée Alfonso, Ilias Kapetanidis, Kapetanidis, Ilias, Alfonso, Dorothée Vera   +3 more
exaly   +2 more sources

Withanolide Z, a New Chlorinated Withanolide fromWithania somnifera

Planta Medica, 2008
Reverse-phase preparative HPLC analysis of the n-butanol fraction of the methanolic extract of Withania somnifera Dunal (leaves) afforded a novel chlorinated withanolide, namely withanolide Z (1), along with four known withanolides, withanolide B (2), withanolide A (3), 27-hydroxywithanolide B (4) and withaferin A (5).
Swapan, Pramanick, Amit, Roy, Shekher, Ghosh, Hemanta K, Majumder, Sibabrata, Mukhopadhyay   +4 more
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Withanolide Artifacts Formed in Methanol

Journal of Natural Products, 2013
Methanol solutions of the main withanolides (6-8) naturally present in Physalis longifolia yielded five artificial withanolides (1-5), including three new compounds (1-3). Withanolides 1 and 2 were identified as intramolecular Michael addition derivatives, while withanolides 3-5 were the result of intermolecular Michael addition.
Cong-Mei, Cao, Huaping, Zhang, Robert J, Gallagher, Barbara N, Timmermann   +3 more
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Withanolides from Jaborosa kurtzii

Journal of Natural Products, 2007
Two new withanolides were isolated and characterized from the aerial parts of Jaborosa kurtzii, namely, jaborosalactone 43 (1), with a spiranoid delta-lactone at C-22, and jaborosalactone 44 (2), a 12-oxowithanolide, which may function as a biosynthetic precursor to 1.
Natalia S, Ramacciotti, Viviana E, Nicotra   +1 more
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Withanolides from Physalis coztomatl

Phytochemistry, 2015
Six withanolides (1-6), as well as two known withanolides (physachenolide D 7 and withanoside VI 8), were isolated from the aerial parts of Physalis coztomatl (Solanaceae). Structural elucidations of 1-6 were achieved through 2D NMR and other spectroscopic techniques, while the structure of 1 was confirmed by X-ray crystallographic analysis.
Zhang, Huaping, Cao, Cong-Mei, Gallagher, Robert J., Day, Victor W., Kindscher, Kelly, Timmermann, Barbara N.   +5 more
openaire   +2 more sources

Biosynthesis of withanolides in Acnistus breviflorus: biogenetic relationships among the main withanolides

Phytochemistry, 1985
Abstract To excised leaves and 15-day-old seedlings of Acnistus breviflorus sodium [1- 14 C]acetate, [2- 14 C]mevalonolactone and [ 14 C-methyl]methionine were administered in separate experiments. From the absolute incorporation values of withaferin A (1), jaborosalactone A (2) and jaborosalactone D (3) isolated at different times after ...
Adriana S. Veleiro, Gerardo Burton, Eduardo G. Gros   +2 more
openaire   +1 more source