Results 81 to 90 of about 869,078 (353)

Progress toward pharmacotherapies for cannabis-use disorder: an evidence-based review

Substance Abuse and Rehabilitation, 2016
Jan Copeland, Izabella Pokorski UNSW Medicine, University of New South Wales, Sydney, NSW, Australia Abstract: Cannabis is the most widely used and variably regulated drug in the world, with increasing trends of use being reported in the US, Australia ...
Copel, J, Pokorski I
doaj  

Ibogaine Detoxification Transitions Opioid and Cocaine Abusers Between Dependence and Abstinence: Clinical Observations and Treatment Outcomes

Frontiers in Pharmacology, 2018
Ibogaine may be effective for transitioning opioid and cocaine dependent individuals to sobriety. American and European self-help groups provided public testimonials that ibogaine alleviated drug craving and opioid withdrawal symptoms after only a single
Deborah C. Mash, Deborah C. Mash, Linda Duque, Bryan Page, Kathleen Allen-Ferdinand   +4 more
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Coning during withdrawal from two fluids of different density in a porous medium

, 2009
The steady response of the interface between two fluids with different density in a porous medium is considered during extraction through a line sink. Supercritical withdrawal, or coning as it is often called, in which both fluids are being withdrawn, is
Hocking, GC, Hocking, G.C., Zhang, Hong, Zhang, H., Hocking, G., Zhang, H   +5 more
core   +1 more source

Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents

Nature Medicine, 2017
Opiates are essential for treating pain, but termination of opiate therapy can cause a debilitating withdrawal syndrome in chronic users. To alleviate or avoid the aversive symptoms of withdrawal, many of these individuals continue to use opiates ...
Nicole E. Burma, R. Bonin, H. Leduc‐Pessah, C. Baimel, Z. F. Cairncross, M. Mousseau, Jhenkruthi Vijaya Shankara, P. Stemkowski, Dinara V. Baimoukhametova, J. Bains, Michael C. Antle, G. Zamponi, C. Cahill, S. Borgland, Y. de Koninck, Tuan Trang   +15 more
semanticscholar   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Turtle Flexion Reflex Motor Patterns Show Windup, Mediated Partly by L-type Calcium Channels

Frontiers in Neural Circuits, 2017
Windup is a form of multisecond temporal summation in which identical stimuli, delivered seconds apart, trigger increasingly strong neuronal responses. L-type Ca2+ channels have been shown to play an important role in the production of windup of spinal ...
Keith P. Johnson, Stephen M. Tran, Emily A. Siegrist, Krishna B. Paidimarri, Matthew S. Elson, Ari Berkowitz, Ari Berkowitz   +6 more
doaj   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Notice of withdrawal [PDF]

British Journal of Dermatology, 2020
L. Frommherz, J. Küsel, A. Zimmer, J. Fischer, C. Has. Skin fragility caused by biallelic KRT10 mutations: an intriguing form of self-improving epidermolytic ichthyosis https://onlinelibrary.wiley.com/doi/10.1111/bjd.18325 The above article from the British Journal of Dermatology, published online on 6 July 2019 in Wiley Online Library ...
openaire   +2 more sources