Results 91 to 100 of about 291,899 (358)

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang   +6 more
wiley   +1 more source

Effect of Rosmarinus officinalis L. Aerial Parts Extract and Fractions on Morphine Withdrawal Syndrome in Mice

open access: yesJournal of Medicinal Plants, 2006
Background: Our previous studies have shown that the aqueous and ethanolic extracts of Rosmarinus officinalis L. aerial parts reduce morphine withdrawal syndrome in mice. Objective: As R. officinalis L.
H Hosseinzadeh   +2 more
doaj  

Opioid Exposed Mothers and Infants in Delaware: Clinical and Legal Considerations [PDF]

open access: yes, 2016
Drug use is on the rise in Delaware, as demonstrated by the continued increase in infants born with neonatal abstinence syndrome. Thoughful, evidence based, and coordinated approaches are necessary to impact this problem.
Paul, MD, David A.   +1 more
core   +1 more source

Effects of human recombinant growth hormone on exercise capacity, cardiac structure, and cardiac function in patients with adult-onset growth hormone deficiency [PDF]

open access: yes, 2017
Objective Epidemiological studies suggest that adult-onset growth hormone deficiency (AGHD) might increase the risk of death from cardiovascular causes. Methods This was a 6-month double-blind, placebo-controlled, randomised, cross-over trial followed by
Atkin, S. L.   +11 more
core   +1 more source

Rapid severe hypertension and organ damage in two‐kidney two‐clip rats produced by different sizes of clips

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Blood pressure increases immediately when the 2K2C rats (made with 0.3, 0.25, and 0.2 mm U‐shaped clips) regain consciousness from anesthesia. 100% of the rats develop hypertension on the day of 2K2C surgery. Blood pressure continues to rise, resulting in severe hypertension and organ damage to the brain, heart, aorta, and kidneys at 1, 2, 4, and 6 ...
Jia‐Sheng Tian   +4 more
wiley   +1 more source

Role of calcium in morphine dependence and naloxone-precipitated withdrawal in mice

open access: yesJournal of Experimental Pharmacology, 2011
Vikas Seth, Prerna Upadhyaya, Vijay Moghe, Mushtaq AhmadDepartment of Pharmacology, Mahatma Gandhi Medical College, Jaipur, Rajasthan, IndiaPurpose: To explore the role of calcium in morphine withdrawal syndrome using various agents affecting calcium ...
Vikas Seth   +3 more
doaj  

Tadalafil improves lean mass and endothelial function in nonobese men with mild ED/LUTS: in vivo and in vitro characterization [PDF]

open access: yes, 2017
PURPOSE: Phosphodiesterase type-5 inhibitor administration in diabetic men with erectile dysfunction (ED) is associated with reduced waist circumference.
Aversa, Antonio   +8 more
core   +1 more source

A mouse model of lung ischemia–reperfusion injury with reversible left hilar entrapment

open access: yesAnimal Models and Experimental Medicine, EarlyView.
A Novel Reversible Left Hilar Entrapment Model for Mouse Lung Ischemia‐Reperfusion Injury with Visual Tracheal Intubation and Live Knot Technique. Abstract Lung ischemia–reperfusion injury (LIRI), an acute lung injury syndrome triggered by lung transplantation or distal organ ischemia, has long been a difficult and hot issue in clinical research.
GuangDong Weng   +4 more
wiley   +1 more source

Evaluating drug withdrawal syndrome risks through food and drug administration adverse event reporting system: a comprehensive disproportionality analysis

open access: yesFrontiers in Pharmacology
ObjectiveThe study aims to identify the drugs associated with drug withdrawal syndrome in the Food and Drug Administration Adverse Event Reporting System (FAERS) and estimate their risks of causing withdrawal syndrome.MethodsAll the data were collected ...
Zheng Zhang   +4 more
doaj   +1 more source

Caffeine and Primary (Migraine) Headaches—Friend or Foe?

open access: yesFrontiers in Neurology, 2019
Background: The actions of caffeine as an antagonist of adenosine receptors have been extensively studied, and there is no doubt that both daily and sporadic dietary consumption of caffeine has substantial biological effects on the nervous system ...
Karl B. Alstadhaug   +3 more
doaj   +1 more source

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