Results 51 to 60 of about 169,796 (292)

The Effects of Quetiapine on Craving and Withdrawal Symptoms in Methamphetamine Abuse: A Randomized, Double-Blind, Placebo-Controlled Trial

International Journal of Medical Toxicology and Forensic Medicine, 2020
Background: Patients with Methamphetamine Abuse (MA) are susceptible to many complications like craving, and withdrawal symptoms. These trials were designed to evaluate the effect of quetiapine administration on craving and withdrawal symptoms in MA ...
Najme Sadat Javdan , Amir Ghaderi , Hamid Reza Banafshe   +2 more
doaj   +1 more source

Neural Circuits between Nodose Ganglion and Pulmonary Neuroendocrine Cells Regulate Lung Inflammatory Responses

Advanced Science, EarlyView.
TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen, Shitao Xie, Zhekai Lin, Caiqi Zhao, Rujia Tao, Yingying Ma, Xiaoyan Chen, Renlan Wu, Qingjian Han, Pengfei Sui, Sheng Wang, Hongbin Ji, Hai Song, Xiaoming Zhang, Yangang Sun, Yuanlin Song, Xiao Su   +16 more
wiley   +1 more source

Status dystonicus resembling the intrathecal baclofen withdrawal syndrome: a case report and review of the literature

Journal of Medical Case Reports, 2010
Introduction Status dystonicus is a rare but life-threatening disorder characterized by increasingly frequent and severe episodes of generalized dystonia that may occur in patients with primary or secondary dystonia.
Muirhead William, Jalloh Ibrahim, Vloeberghs Michael   +2 more
doaj   +1 more source

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Pengaruh Pemeberian Ekstrak Etanol Delphinium Grandifl orum Terhadap Tanda Somatik dan Tanda Afektif Nicotine Withdrawal Syndrome pada Tikus Sprague Dawley Betina yang Diberi Nikotin Peroral

IJNP (Indonesian Journal of Nursing Practices), 2014
Background. Nicotine abstinence will lead nicotine withdrawal syndrome in somatic signs and aff  ective signs. Somatic signs such as body weight change. Aff  ective signs such as sign of anxiety.
Nurvita Risdiana
doaj   +1 more source

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

Advanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu, Jiabi Liang, Linda Zeng, Shuping Zhong, Xueling Fang, Yating Xu, Yongjian Wu, Xi Huang   +7 more
wiley   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Effect of Zhumeria majdae Rech. f. & Wendelbo Aerial Parts Extracts and Fractions on Morphine Withdrawal Syndrome in Mice

Journal of Medicinal Plants, 2007
Background: Zhumeria majdae showed antinociceptive and anti-inflammatory activity. The antinociceptive effect was inhibited by naloxone in hot-plate test. Objective: As Z.
H Hosseinzadeh, M Ramezani, M Ghorbani
doaj  

Assessment of a modified MINDS ‐based protocol for management of alcohol withdrawal syndrome on an inpatient medical service [PDF]

, 2023
Kevin M. Krcmarik, Benjamin J. Hulley, Jiayi Huang, Derek Juang, Peter E. Cadman, Charisma Urbiztondo, Christine Vo, Jaclyn Vargas, Ramin Motarjemi, Tarlan Moinizandi, Brian Kwan   +10 more
openalex   +1 more source

The alcohol withdrawal syndrome

Annals of Emergency Medicine, 1982
Summary The alcohol withdrawal syndrome represents an acute medical emergency of probable multifactorial cause. The emergency physician who sees only one point in the spectrum of the patient's disease must be aware of the other clinical entities simulating its presentation.
openaire   +3 more sources