Results 251 to 260 of about 423,254 (279)
Double-edged-sword effect of bisphosphonates on the osteogenic differentiation of human periodontal ligament stem cells. [PDF]
Front PharmacolLi M +6 more
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Photoperiodic regulation of Wnts in spermatogenesis of Brandt's vole (Lasiopodomys brandtii). [PDF]
Front ZoolZhao L +8 more
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Mast Cells Inhibit Stem Cell-driven Epithelial Repair in Inflammatory Bowel Disease via Suppressing Wnt/lrp6/β-Catenin Signaling Pathway. [PDF]
Cell Mol Gastroenterol HepatolZhang T +5 more
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Planar cell polarity emerges through polarized accumulation of Wnt11. [PDF]
Sci AdvMii Y +10 more
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WNT signalling and haematopoiesis: a WNT–WNT situation
Nature Reviews Immunology, 2005The evolutionarily conserved WNT-signalling pathway has pivotal roles during the development of many organ systems, and dysregulated WNT signalling is a key factor in the initiation of various tumours. Recent studies have implicated a role for WNT signal transduction at several stages of lymphocyte development and in the self-renewal of haematopoietic ...
Staal, Frank, Clevers, HC
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Science Signaling, 2003
In the canonical Wnt signaling pathway, Wnts cause stabilization of β-catenin and consequent changes in gene expression. But not all Wnts appear to signal in this way. Developmental actions of Wnt-5, for example, appear not to be mediated by β-catenin, and now two papers show that Wnt-5 actually antagonizes canonical Wnt signaling ...
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In the canonical Wnt signaling pathway, Wnts cause stabilization of β-catenin and consequent changes in gene expression. But not all Wnts appear to signal in this way. Developmental actions of Wnt-5, for example, appear not to be mediated by β-catenin, and now two papers show that Wnt-5 actually antagonizes canonical Wnt signaling ...
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Trends in Genetics, 2004
Recent research on the WNT signaling pathway warrants a reassessment of the basic mechanism that transmits signal from the membrane-bound receptor to the nucleus. This article incorporates these findings into a revised model for pathway activation. We propose that the control of Axin stability, rather than the control of ZW3 phosphorylation of the ...
Nicholas S, Tolwinski, Eric, Wieschaus
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Recent research on the WNT signaling pathway warrants a reassessment of the basic mechanism that transmits signal from the membrane-bound receptor to the nucleus. This article incorporates these findings into a revised model for pathway activation. We propose that the control of Axin stability, rather than the control of ZW3 phosphorylation of the ...
Nicholas S, Tolwinski, Eric, Wieschaus
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Targeting Oncogenic WNT Signalling with WNT Signalling-Derived Peptides
2021WNT signalling is known to be a crucial regulator of embryonic development and tissue homeostasis. Aberrant expression of WNT signalling elements or their mutations has been implicated in carcinogenesis and/or the progression of several different cancer types.
Vikas, Yadav +3 more
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