Results 221 to 230 of about 1,449,284 (254)

RBM15-MKL1 fusion protein promotes leukemia via m6A methylation and Wnt pathway activation. [PDF]

Blood
Mayday MY, Biancon G, Wei M, Ramirez C, Moratti I, Pintado-Urbanc AP, Espinosa JA, Chen M, Wang L, Simon MD, Ofir-Rosenfeld Y, Rausch O, Tebaldi T, Halene S, Krause DS.   +14 more
europepmc   +1 more source

Nanofabricated Biomaterials Model Tumor Extracellular Matrix Topography

Advanced NanoBiomed Research, EarlyView.
The unique structure and composition of the tumor microenvironment and its associated extracellular matrix (ECM) exert profound effects on cancer cell behavior that are difficult to model in vitro. This perspective discusses the utility of nanofabricated biosubstrates, such as the novel collagen‐coated nanogrooved array, for recapitulating the ...
Vic Zamloot, JinSeok Park
wiley   +1 more source

Cancer-associated fibroblasts enhance colorectal cancer lymphatic metastasis via CLEC11A/LGR5-mediated WNT pathway activation. [PDF]

J Clin Invest
Zhang C, Pan T, Zhang Y, Wu Y, Zuo A, Liu S, Ba Y, Liu B, Yang S, Chen Y, Xu H, Luo P, Cheng Q, Weng S, Liu L, Zhou X, Ning J, Han X, Deng J, Liu Z.   +19 more
europepmc   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

Characterization and Cytotoxicity of West Java Coffee Extracts, Chlorogenic Acid, Caffeine on MDA-MB-231, MCF-7 Cell Lines, and Their Impact on <i>MYC</i> and <i>AXIN2</i> Wnt Pathway Gene Expression. [PDF]

Breast Cancer (Dove Med Press)
Aborziza M, Zuhrotun A, Novianto A, Amalia R, Fakih TM, Muchtaridi M.   +5 more
europepmc   +1 more source

Supramolecular Cadmium‐Telluride Proteoliposomal Assemblies for Real‐Time Detection of Protein‐Catalyzed Pt(II)‐Complexes Transmembrane Translocation: Cu(I)‐Pumps Are Electrogenic Pt(II)‐Drug Uniporters

Angewandte Chemie, EarlyView.
Supramolecular mercaptosuccinic acid‐capped CdTe core‐type quantum dot‐encapsulated proteoliposome assemblies (MSA‐CdTe QD PLs) have been developed to study and unambiguously demonstrate real‐time transporter‐mediated turnover translocation of Pt(II)‐based complexes by transmembrane Cu(I) P‐type ATPase pumps (CopA).
Madujika A. Horadigala Gamage, Alessandra Barbanente, Nadeesha T. Liyana Withanage, Yalini H. Wijesundara, Jeremiah J. Gassensmith, Fabio Arnesano, Giovanni Natile, Gabriele Meloni   +7 more
wiley   +1 more source

Case Report: Novel combinatorial factors in the WNT pathway in a pediatric case of valvular aortic stenosis from Lebanon: a brief report. [PDF]

Front Cardiovasc Med
Ataya W, Mohammed F, Arabi M, Bitar F, Nemer G.   +4 more
europepmc   +1 more source

Transcriptional feedback targeting Wnt pathway components reveals hidden heterogeneity in C. elegans seam cell lineages

Ferrando-Marco M, Berger S, Barkoulas M.
europepmc   +1 more source

Exploring WNT pathway dysregulation in serrated colorectal cancer for improved diagnostic and therapeutic strategies. [PDF]

Front Genet
Zhu F, Yan HHN, Tong Y, Zhao Y.
europepmc   +1 more source