Exploring the effect of Er, Cr: YSGG laser combined with GBR on osteogenesis at extraction sockets in rats with severe periodontitis via the Wnt/β-catenin pathway. [PDF]
Lasers Med SciGuo Y, Wang Y, Zhang G, Kong L, Yang S.
europepmc +1 more source
Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension in <i>Xenopus</i>. [PDF]
ElifeSeo HS +11 more
europepmc +1 more source
STEAP1 Suppresses Oral Squamous Cell Carcinoma by Targeting Wnt/β-Catenin Signalling and EMT. [PDF]
Cancer MedJin K +5 more
europepmc +1 more source
Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review). [PDF]
Oncol RepLi H, Song S, Wang L, Liu Q.
europepmc +1 more source
Patchouli alcohol suppresses <i>Helicobacter pylori</i>-associated gastric cancer by activating PXR to inhibit the Wnt/β-catenin pathway and EMT. [PDF]
Front PharmacolZhang X +5 more
europepmc +1 more source
Related searches:
Wnt Proteins in Mammary Development and Cancer
Journal of Mammary Gland Biology and Neoplasia, 2004Secreted proteins of the Wnt family play widespread roles in the regulation of embryonic development, and aberrant activation of the canonical Wnt/beta-catenin pathway is one of the most frequent signaling abnormalities known in human cancer. While the consequences of Wnt signaling in development are diverse at the cellular level, they are often ...
Anthony Brown
exaly +4 more sources
Fatty acylation of Wnt proteins
Nature Chemical Biology, 2016Wnt proteins are critical regulators of signaling networks during embryonic development and in adult tissue homeostasis. The generation of active Wnt proteins requires their regulated secretion into the extracellular space. Once secreted, Wnts signal through the cell surface via receptor binding on Wnt-receiving cells, a mechanism that is prevalent in ...
Aaron H, Nile, Rami N, Hannoush
openaire +2 more sources
The role of Wnt proteins in arthritis
Nature Clinical Practice Rheumatology, 2008Wnt proteins regulate organ development, tumorigenesis and bone homeostasis, among other functions. The binding of Wnt proteins to plasma membrane receptors on mesenchymal cells induces the differentiation of these cells into the osteoblast lineage and thereby supports bone formation.
Georg, Schett +2 more
openaire +2 more sources
Multiplicity of the interactions of Wnt proteins and their receptors
Cellular Signalling, 2007Wnts are secreted proteins that are essential for a wide array of developmental and physiological processes. They signal across the plasma membranes by interacting with serpentine receptors of the Frizzled (Fz) family and members of the low-density-lipoprotein receptor-related protein (LRP) family.
Akira, Kikuchi +2 more
openaire +2 more sources
Active Wnt proteins are secreted on exosomes
Nature Cell Biology, 2012Wnt signalling has important roles during development and in many diseases. As morphogens, hydrophobic Wnt proteins exert their function over a distance to induce patterning and cell differentiation decisions. Recent studies have identified several factors that are required for the secretion of Wnt proteins; however, how Wnts travel in the ...
Julia Christina, Gross +3 more
openaire +2 more sources