Results 251 to 260 of about 336,645 (300)

Long Noncoding RNA H19 Mediates STAT3‐Dependent Activation of Keratinocytes and Fibroblasts in Systemic Sclerosis Skin

Arthritis &Rheumatology, EarlyView.
Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz, Christopher W. Wasson, Rebecca L. Ross, Francesco Del Galdo   +3 more
wiley   +1 more source

Selective and Potent Peptide Binders of RNF43 for Wnt Signaling Inhibition. [PDF]

ACS Cent Sci
Hwang S, Salcedo PF, Korcari A, Nicoludis JM, Valdivia EM, Peng L, Balana AT, Mak J, Crittenden CM, Famili A, Liu P, Castillo-Azofeifa D, Hannoush RN, Miller SE, Schroeder CI, Gao X.   +15 more
europepmc   +1 more source

SRCIN1 promotes thyroid carcinoma growth by activating Wnt signaling pathway. [PDF]

Sci Rep
Han C.
europepmc   +1 more source

Localized Wnt-signaling promotes asymmetric NuMA-dependent oriented divisions and unequal apportioning of mitochondria. [PDF]

Nat Commun
Eli S, Rauso G, Ghezzi P, Szczerkowski JLA, Bruzzi M, Rizzelli F, Iommazzo F, Loffreda A, Castagna F, Donà F, Gaddoni C, Dondi A, Marenda M, Rodighiero S, Tournier P, Lavagnino Z, Parazzoli D, Gauthier NC, Tamburri S, Pasini D, Habib SJ, Mapelli M.   +21 more
europepmc   +1 more source

The ratio of Wnt signaling activity to Sox2 transcription factor levels predicts neuromesodermal fate potential. [PDF]

Development
Morabito RM, Tatarakis D, Swick R, Stettnisch S, Nayak PK, Schilling TF, Horsfield JA, Martin BL.   +7 more
europepmc   +1 more source

Lithium Chloride rescues Monensin-potentiated Wnt signaling inhibition in inflammatory bone loss in rats. [PDF]

Braz Dent J
Chagas A, Gomes S, Oliveira D, Viana K, Chaves J, Martins C, Costa V, Angelino G, Azevedo S, Almeida D, Sena JM, Gondim D, Leitão R, Marques M, Goes P.   +14 more
europepmc   +1 more source

[Expression of Concern] Insulin‑dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation. [PDF]

Int J Mol Med
Hie M, Iitsuka N, Otsuka T, Tsukamoto I.
europepmc   +1 more source

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Targeting Oncogenic WNT Signalling with WNT Signalling-Derived Peptides

2021
WNT signalling is known to be a crucial regulator of embryonic development and tissue homeostasis. Aberrant expression of WNT signalling elements or their mutations has been implicated in carcinogenesis and/or the progression of several different cancer types.
Vikas, Yadav, Njainday, Jobe, Lubna, Mehdawi, Tommy, Andersson   +3 more
openaire   +2 more sources

Rethinking WNT signaling

Trends in Genetics, 2004
Recent research on the WNT signaling pathway warrants a reassessment of the basic mechanism that transmits signal from the membrane-bound receptor to the nucleus. This article incorporates these findings into a revised model for pathway activation. We propose that the control of Axin stability, rather than the control of ZW3 phosphorylation of the ...
Nicholas S, Tolwinski, Eric, Wieschaus
openaire   +2 more sources