Results 231 to 240 of about 1,133,912 (305)

Metastasis Pattern‐Specific Biomarkers and Therapeutic Targets in Gastric Cancer: From Surgical Specimens to Clinical Translation

Annals of Gastroenterological Surgery, EarlyView.
Gastric cancer metastasis should be considered according to its anatomical route, because lymphatic, peritoneal, and hematogenous dissemination involve partly distinct molecular mechanisms. This review summarizes metastasis pattern‐associated and pattern‐specific molecules identified using surgical specimens, evaluates their evidence and translational ...
Mitsuro Kanda
wiley   +1 more source

Supramolecular Cadmium‐Telluride Proteoliposomal Assemblies for Real‐Time Detection of Protein‐Catalyzed Pt(II)‐Complexes Transmembrane Translocation: Cu(I)‐Pumps Are Electrogenic Pt(II)‐Drug Uniporters

Angewandte Chemie, EarlyView.
Supramolecular mercaptosuccinic acid‐capped CdTe core‐type quantum dot‐encapsulated proteoliposome assemblies (MSA‐CdTe QD PLs) have been developed to study and unambiguously demonstrate real‐time transporter‐mediated turnover translocation of Pt(II)‐based complexes by transmembrane Cu(I) P‐type ATPase pumps (CopA).
Madujika A. Horadigala Gamage, Alessandra Barbanente, Nadeesha T. Liyana Withanage, Yalini H. Wijesundara, Jeremiah J. Gassensmith, Fabio Arnesano, Giovanni Natile, Gabriele Meloni   +7 more
wiley   +2 more sources

Wnt signaling regulates passive cell competition in the retina by inducing differential cell adhesion. [PDF]

Nat Commun
Min X, Chow A, Mao Y, Wu H, Makrides N, Bock J, Wu Y, Almonte Y, Tao C, Zhang X.   +9 more
europepmc   +1 more source

A Generative AI Framework to Predict Cardiomyocyte Contraction Function From Single Static Images

Advanced Intelligent Discovery, EarlyView.
A single static hiPSC‐cardiomyocyte image is fed into a U‐Net‐GAN framework, which directly predicts a pixel‐resolved contraction heatmap without time‐lapse imaging. StyleGAN2‐generated synthetic cell–heatmap pairs augment training, improving prediction fidelity (SSIM = 0.84).
Andrew Kowalczewski, Chenyan Wang, Xinrui Wang, Huaxiao Yang, Zhao Qin, Zhen Ma   +5 more
wiley   +1 more source

L-DOPA enhances iRPE differentiation via Wnt signaling and improves cytotherapy for retinal degradation. [PDF]

Stem Cell Res Ther
Ke Y, Zhao Y, Feng Q, Xue M, Zhang M, Tan L, Ren X.   +6 more
europepmc   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

Wnt signaling-mediated activation of cancer cell stemness in thoracic SMARCA4-deficient undifferentiated tumor cells. [PDF]

Cell Death Discov
Xu Y, Wang L, Zhang H, Liang L, Han H, Xiao T, Zhang C, He Q, Yu Z, Gao J.   +9 more
europepmc   +1 more source

Wnt signaling promotes inflammation and EMT-associated gene expression in mesenchymal TNBC. [PDF]

Sci Rep
García-Areas R, Girard E, Lasla H, Raynal V, Pandey AK, Servant N, Jézéquel P, Dubois T.   +7 more
europepmc   +1 more source

Wnt signaling patterns a central-peripheral body axis in the early-diverging metazoan Trichoplax adhaerens. [PDF]

Mol Biol Evol
Di G, Jin M, Li W, Yuan M, Zhang Y, Zhao C.   +5 more
europepmc   +1 more source