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Wnt signaling during tooth replacement in zebrafish (Danio rerio): pitfalls and perspectives [PDF]

open access: yesFrontiers in Physiology, 2014
The canonical (β-catenin dependent) Wnt signaling pathway has emerged as a likely candidate for regulating tooth replacement in continuously renewing dentitions.
Ann eHuysseune   +2 more
doaj   +4 more sources

Wnt signaling in colorectal cancer: pathogenic role and therapeutic target

open access: yesMolecular Cancer, 2022
Background The Wnt signaling pathway is a complex network of protein interactions that functions most commonly in embryonic development and cancer, but is also involved in normal physiological processes in adults.
Hui Zhao   +7 more
doaj   +1 more source

Squalene activates Wnt/β-Catenin signaling pathway to mediate NF-κB pathway to regulate inflammatory response and disease resistance in hybrid grouper (♀ Epinephelus fuscoguttatus × ♂ E. lanceolatu)

open access: yesAquaculture Reports, 2023
We previously found that squalene may influence immunity of grouper by affecting the Wnt/β-Catenin signaling pathway, but the exact mechanism is uncertain.
Xiaobo Yan   +8 more
doaj   +1 more source

Regulation of Avian Leukosis Virus Subgroup J Replication by Wnt/β-Catenin Signaling Pathway

open access: yesViruses, 2021
Wnt/β-catenin signaling is a highly conserved pathway related to a variety of biological processes in different cells. The regulation of replication of various viruses by Wnt/β-catenin signaling pathway has been reported. However, the interaction between
Dandan Qiao   +7 more
doaj   +1 more source

Loss of pancreas upon activated Wnt signaling is concomitant with emergence of gastrointestinal identity [PDF]

open access: yes, 2016
Organ formation is achieved through the complex interplay between signaling pathways and transcriptional cascades. The canonical Wnt signaling pathway plays multiple roles during embryonic development including patterning, proliferation and ...
Cano, David A.   +7 more
core   +10 more sources

Wnt/β-catenin signaling pathway inhibits the proliferation and apoptosis of U87 glioma cells via different mechanisms. [PDF]

open access: yesPLoS ONE, 2017
The Wnt signaling pathway is necessary for the development of the central nervous system and is associated with tumorigenesis in various cancers. However, the mechanism of the Wnt signaling pathway in glioma cells has yet to be elucidated. Small-molecule
Liyang Gao   +6 more
doaj   +1 more source

Regulation of the WNT-CTNNB1 signaling pathway by severe fever with thrombocytopenia syndrome virus in a cap-snatching manner

open access: yesmBio, 2023
The segmented negative-strand RNA viruses (sNSVs) include highly pathogenic human and animal viruses such as Lassa virus (LASV), severe fever with thrombocytopenia syndrome virus (SFTSV), and influenza A virus (IAV).
Xia-Ming Jiang   +9 more
doaj   +1 more source

Interaction of viral oncogenic proteins with the Wnt signaling pathway [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2018
It is estimated that up to 20% of all types of human cancers worldwide are attributed to viruses. The genome of oncogenic viruses carries genes that have protein products that act as oncoproteins in cell proliferation and transformation.
Sayyad Khanizadeh   +4 more
doaj   +1 more source

Expression Levels of WNT Signaling Pathway Genes During Early Tooth Development

open access: yesOrganogenesis, 2023
It is known to all that Wnt signaling pathway plays an important role in the early development of tooth. Our previous research found that Wnt signaling pathway played crucial roles in dental development, and mutations in antagonist of Wnt signaling ...
Yuhan Song   +4 more
doaj   +1 more source

A CRISPR knockout screen reveals new regulators of canonical Wnt signaling

open access: yesOncogenesis, 2021
The Wnt signaling pathways play fundamental roles during both development and adult homeostasis. Aberrant activation of the canonical Wnt signal transduction pathway is involved in many diseases including cancer, and is especially implicated in the ...
Tamar Evron   +9 more
doaj   +1 more source

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