Results 31 to 40 of about 186,141 (260)
The recent progress of peptide regulators for the Wnt/β-catenin signaling pathway
Frontiers in Medicine, 2023 Wnt signaling plays an important role in many biological processes such as stem cell self-renewal, cell proliferation, migration, and differentiation.
Nan Zhang +6 more
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Wnt Signaling in Hepatocellular Carcinoma: Biological Mechanisms and Therapeutic Opportunities
CellsHepatocellular carcinoma (HCC), characterized by significant morbidity and mortality rates, poses a substantial threat to human health. The expression of ligands and receptors within the classical and non-classical Wnt signaling pathways plays an ...
Yingying Zhu, Yajing He, Runliang Gan
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Wnt signaling pathway in development and cancer. [PDF]
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2018 Wnt signaling pathway is one of the most important signaling pathways. The complexity of Wnt signals and their functional role is crucial in development and growth. It is the most active during embryogenesis facilitating new organism formation by cell differentiation, polarization and migration.
Bartłomiej Taciak +4 more
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Autophagy and the Wnt signaling pathway: A focus on Wnt/β-catenin signaling
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2021 Cellular homeostasis and adaptation to various environmental conditions are importantly regulated by the sophisticated mechanism of autophagy and its crosstalk with Wnt signaling and other developmental pathways. Both autophagy and Wnt signaling are involved in embryogenesis and differentiation. Autophagy is responsible for degradation and recycling of
Shahrokh, Lorzadeh +3 more
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Wnt Signaling Pathway in Oral Lesions
Journal of the Pakistan Medical Association, 2019 Wingless-Integrated/Beta-catenin (WNT/-catenin) signalling pathway is one of the principal intercellular signalling pathways in humans. It plays an intrinsic role in the cellular proliferation, differentiation and regeneration along with many other cellular functions.
Iqra, Ejaz, Sarah, Ghafoor
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Secreted antagonists of the Wnt signalling pathway [PDF]
Journal of Cell Science, 2003 The extracellular antagonists of the Wnt signalling pathway can be divided into two broad classes. Both classes of molecule prevent ligand-receptor interactions, but by different mechanisms: members of the first class, which include the sFRP (secreted Frizzled-related protein) family, WIF (Wnt inhibitory factor)-1 and Cerberus, primarily bind to Wnt ...
Yoshiaki, Kawano, Robert, Kypta
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Genes and DiseasesThe evolutionarily conserved Wnt signaling pathway plays a central role in development and adult tissue homeostasis across species. Wnt proteins are secreted, lipid-modified signaling molecules that activate the canonical (β-catenin dependent) and non ...
Michael Yu +18 more
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Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
Pediatric Blood &Cancer, EarlyView.ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
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Role of microRNAs in regulation of WNT signaling pathway in urothelial and prostate cancers
Egyptian Journal of Medical Human Genetics, 2022 Background Urothelial cancer (UC) and prostate cancer (PCa) are the most common cancers among men with a high ratio of mortality in advanced-stages.
Mehdi Montazer +3 more
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