Results 11 to 20 of about 1,031,479 (367)
Modulating the wnt signaling pathway with small molecules [PDF]
Protein Science, 2017 AbstractWnt signaling is a critical component during embryonic development and also plays an important role in regulating adult tissue homeostasis. Abnormal activation of Wnt signaling has been implicated in many cancers, while reduced activity of Wnt signaling leads to poor wound healing and structural formations.
F. Tran, Jie J. Zheng
semanticscholar +6 more sources
Wnt signaling during tooth replacement in zebrafish (Danio rerio): pitfalls and perspectives [PDF]
Frontiers in Physiology, 2014 The canonical (β-catenin dependent) Wnt signaling pathway has emerged as a likely candidate for regulating tooth replacement in continuously renewing dentitions.
Ann eHuysseune +2 more
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Wnt and the Wnt signaling pathway in bone development and disease. [PDF]
Frontiers in Bioscience, 2014 Wnt signaling affects both bone modeling, which occurs during development, and bone remodeling, which is a lifelong process involving tissue renewal. Wnt signals are especially known to affect the differentiation of osteoblasts.
Yiping Wang +6 more
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Wnt signal transduction pathway and apoptosis: a review [PDF]
Cancer Cell International, 2010 The association between the wnt signaling pathway and apoptosis has become more firmly established in the recent scientific literature. Many reports indicate that the wnt signaling pathway regulates apoptosis through a variety of mechanisms. The activity
Pećina-Šlaus Nives
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The Wnt signalling pathway [PDF]
Journal of Cell Science, 2002 Recent advances in the field require an update of our Wnt pathway scheme ( [Hulsken and Behrens, 2000][1]). Intracellular signaling of the Wnt pathway diversifies into at least three branches: (1) the β-catenin pathway (canonical Wnt pathway, blue), which activates target genes in the nucleus ...
Juergen Behrens, Joerg Huelsken
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Loss of pancreas upon activated Wnt signaling is concomitant with emergence of gastrointestinal identity [PDF]
, 2016 Organ formation is achieved through the complex interplay between signaling pathways and transcriptional cascades. The canonical Wnt signaling pathway plays multiple roles during embryonic development including patterning, proliferation and ...
Cano, David A. +7 more
core +11 more sources
Wnt signaling in colorectal cancer: pathogenic role and therapeutic target
Molecular Cancer, 2022 Background The Wnt signaling pathway is a complex network of protein interactions that functions most commonly in embryonic development and cancer, but is also involved in normal physiological processes in adults.
Hui Zhao +7 more
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Roles of the Wnt Signaling Pathway in Head and Neck Squamous Cell Carcinoma
Frontiers in Molecular Biosciences, 2021 Head and neck squamous cell carcinoma (HNSCC) is the most common type of head and neck tumor. It is a high incidence malignant tumor associated with a low survival rate and limited treatment options.
Jing Xie +3 more
semanticscholar +1 more source
Regulation of Avian Leukosis Virus Subgroup J Replication by Wnt/β-Catenin Signaling Pathway
Viruses, 2021 Wnt/β-catenin signaling is a highly conserved pathway related to a variety of biological processes in different cells. The regulation of replication of various viruses by Wnt/β-catenin signaling pathway has been reported. However, the interaction between
Dandan Qiao +7 more
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Wnt signal transduction pathways [PDF]
Organogenesis, 2008 The Wnt signaling pathway is an ancient and evolutionarily conserved pathway that regulates crucial aspects of cell fate determination, cell migration, cell polarity, neural patterning and organogenesis during embryonic development. The Wnts are secreted glycoproteins and comprise a large family of nineteen proteins in humans hinting to a daunting ...
Raymond Habas, Yuko Komiya
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