Results 71 to 80 of about 3,063,204 (302)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
BMC Psychiatry, 2019 Background Expert psychiatrists conducting work disability evaluations often disagree on work capacity (WC) when assessing the same patient. More structured and standardised evaluations focusing on function could improve agreement. The RELY studies aimed
Regina Kunz +15 more
doaj +1 more source
Di-san junyi daxue xuebao, 2020 Objective To compare the accuracy of different indexes based on heart rate and blood oxygen saturation level for evaluating aerobic exercise capacity among the military staff serving in high-altitude regions.
LI Peng +4 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Re-Orienting Compagnies's Hiring Behaviour : An Innovative 'Back-To-Work' Method in France [PDF]
Current ‘back-to-work' programmes, particularly in France, tend to be built on a concept of personal responsibility for (long-term) unemployment and follow an ‘adaptive' approach: improving the ‘employability' of the unemployed, which is seen as an ...
Marie Salognon
core
Aging and Economic Security Evaluation: Crosscutting Lessons Learned [PDF]
, 2016 This evaluation of Atlantic's grantmaking to support the economic security of low-income elders identifies elements most likely to help advance a policy agenda when working in a politically charged environment: Use a state-by-state approach and target ...
Andrea Anderson, Tanja Kubas-Meyer
core
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Districts and Data: Developing Capacity for Effective Data Use [PDF]
, 2014 The development of large and interconnected data sets has awakened educators to the value of strategically using data to inform education policy and improve instruction. Recognizing that using data effectively is critical to improving student achievement,
Cassie Pickens Jewell +2 more
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Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source