Results 61 to 70 of about 716,253 (307)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Overdose education and naloxone distribution in jails: Examining the impact of the Communities That HEAL intervention in 4 states

Health & Justice
Background Opioid-related overdose is the leading cause of mortality among individuals recently released from incarceration in the U.S. Naloxone is an FDA-approved opioid antagonist medication designed to rapidly reverse opioid overdose. Despite evidence
Timothy Hunt, Carrie B. Oser, Peter D. Friedmann, Nicole Mack, Peter Balvanz, Bridget Freisthler, Redonna K Chandler, Karli Hochstatter, Daniel R. Harris, LaShawn Glasgow, Lauren D’Costa, Mary R. Russo, Barry Eggleston, Arnie Aldridge, Paul Bellair, Allyson G. Cogan, James L. David, Nabila El-Bassel, Dawn Goddard-Eckrich, Steve Gomori, Holly Hagan, Steve Hanson, JaNae Holloway, Elizabeth N. Kinnard, Charlie Knott, Michael W. Konstan, Sharon L. Walsh, Patricia A. LeBaron, Michael S. Lyons, Margaret McGladrey, Joan Papp, Sean M. Murphy, Sandra Springer, Emmanuel Oga, Michele Staton, Elizabeth Schady, Fernando Montero, Hilary L. Surratt, Danelle Stevens-Watkins, John Winhusen, Gary A. Zarkin, Greer A. Hamilton, Joel G. Sprunger   +42 more
doaj   +1 more source

HUBUNGAN WORK-FAMILY ENRICHMENT DENGAN WORK ENGAGEMENT PADA PERAWAT WANITA

Jurnal Psikologi Ulayat: Indonesian Journal of Indigenous Psychology, 2015
— A young, married nurse has to play dual roles in her life: in a work and family setting. Playing dual roles does not always end in a conflict, but can also enrich one’s experience and increase one’s quality of life.
C. M. Indah Soca R. Kuntari
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

A ‘Post‐Work’ World: Geographical Engagements with the Future of Work [PDF]

The Political Quarterly, 2019
AbstractThis article reviews geographical research on labour market changes that pose a challenge to ‘work’ as a compelling category of analysis. Drawing inspiration from feminist scholarship that has sought to develop a frame for thinking about the concept of work so that other activities outside employment are recognised, it considers what everyday ...
MacLeavy, J, Lapworth, A
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Religiosity and work engagement: Workload as a moderator

Stress and Health, 2021
AbstractBased on job demands‐resources (JD‐R) theory, this study examines the relationship between religiosity‐from an Islamic lens‐and work engagement, and the moderating role of workload on the relationship between these constructs. The results of a survey of 381 Muslim employees in Jordanian telecoms reveal that religiosity is positively related to ...
Abualigah, Ahmad, Davies, Julie, Harrington, Shelley   +2 more
openaire   +6 more sources

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

New Principles for Work Engagement in Switzerland

Administrative Sciences
Global employee work engagement remains critically low, with only 21% of employees engaged worldwide in 2024 and Switzerland ranking near the bottom in Europe at 8%.
Dalowar Hossan, Qing Zhang, Bert Wolfs, Noor-E-Medina Suraiya Jesmin   +3 more
doaj   +1 more source