Results 101 to 110 of about 16,598,865 (356)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Severity of Work Disability and Work [PDF]

This paper analyzes the effect of severity of disability on labour force participation by using a self-reported work limitation scale. A dynamic labour force participation model is used to capture the feedback effect of past participation on current ...
Oguzoglu, Umut
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The Effect of Total Hip Arthroplasty on Sports and Work Participation: A Systematic Review and Meta-Analysis

Sports Medicine, 2018
BackgroundTotal hip arthroplasty (THA) is a successful procedure to treat end-stage hip osteoarthritis. The procedure is increasingly performed in adults of working age, who often wish to return to sports (RTS) and return to work (RTW).
A. Hoorntje, A. Hoorntje, Kim Y Janssen, S. Bolder, K. Koenraadt, J. Daams, L. Blankevoort, L. Blankevoort, G. Kerkhoffs, G. Kerkhoffs, P. Kuijer   +10 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

A qualitative study of young workers’ experience of the psychosocial work environment and how this affects their mental health

BMC Public Health
Background The evidence base for the relationship between psychosocial work factors and mental health focuses primarily on the general working population but little is known about young workers.
Malte van Veen, Roosmarijn MC Schelvis, Paulien M Bongers, Karen M Oude Hengel, Cécile RL Boot   +4 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Work, authority and participation : the scenario of circular organizing [PDF]

Two antagonistic tendencies in the way work is organized can be observed in Europe and the North-American continent. First, there is the growing tendency toward more efficient and flexible modes of organizing by way of a clear (re)distribution of ...
Romme,A. Georges L.
core   +1 more source

Propositions and alignment as constructs of cooperation in multiprofessional–client meeting interactions

Nordic Social Work Research
Finland is currently amidst a significant national healthcare and social welfare reform, with the goals of multiprofessional-integrated work and client centredness, necessitating more detailed research on multiprofessional – client meetings as joint ...
Tuuli Kalari
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source