Results 71 to 80 of about 52,185 (265)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Remote Work and the Psychosocial Work Environment: The Role of Contact

Nordic Journal of Working Life Studies
Remote work is fundamentally changing the organization of work, replacing the physical work environment of the office and creating a spatial distance between colleagues.
Mari Holm Ingelsrud, Vilde Hoff Bernstrøm, Wendy Nilsen   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Hospital Mergers in Norway: Employee Health and Turnover to Three Destinations

Nordic Journal of Working Life Studies, 2017
This article investigates the probability of turnover to three destinations following hospital merg- ers: within the hospital sector, out of the hospital sector, and out of work.
Mari Holm Ingelsrud
doaj   +1 more source

Working from home environments to enhance wellbeing and productivity

This presentation examines the essential qualities of effective home working en- vironments and their impact on well-being and productivity.
Abuzeinab, Amal, Dye, Abigail, Ogunbode, Charles, Ghaziani, Rokhshid   +3 more
openaire   +1 more source

PSYCHOSOCIAL WORK ENVIRONMENT AND EMPLOYEE WELLBEING: STRESS AND PERSONALITY EFFECTS

Veredas do Direito
The study examines the impact of the psychosocial work environment, measured as a high-order construct, on employee wellbeing, with stress as a mediator and personality as a moderator.  The study collects the data from 230 employees across multiple sectors in Pakistan.
Waqar Akbar, Manoj Kumar, Muhammad Asad Ali, Muhammad Mubeen, Zawiah Mat   +4 more
openaire   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Paid Sick Leave as a Means to Reduce Sickness Presenteeism Among Physicians

Nordic Journal of Working Life Studies, 2017
Recurrent international data show that physicians often attend work while ill, termed sickness presenteeism. The current study investigated if sickness presenteeism scores among European physicians varied according to national paid sick leave legislation.
Ingrid Steen Rostad, Ann Fridner, Marie Gustafsson Sendén, Lise Tevik Løvseth   +3 more
doaj   +1 more source

Noise exposure, satisfaction with the working environment, and the wellbeing process [PDF]

, 2021
Langer, Jennifer, Taylour, Jim, Smith, Andrew   +2 more
openaire   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source