Results 211 to 220 of about 1,054 (243)

Clinical Presentation and Evolution of Isolated Focal and Segmental Dystonia in Adults - 20 Years' Experience from a Botulinum Toxin Clinic. [PDF]

Ann Indian Acad Neurol
Vijayaraghavan A, Krishnan S, Patel KS, Mohan SK, Radhakrishnan V, Sanalkumar A, Sarma SG, Cherian A, Puthanveedu DK.   +8 more
europepmc   +1 more source

Deficient Homeostatic Regulation of Practice-Dependent Plasticity in Writer’s Cramp

, 2010
Carmen Terranova, Jun-Suk Kang, Angelo Quartarone, Ulf Ziemann, Rüdiger Hilker   +4 more
core   +1 more source

Nuclear factor of activated T cells as a driver of tumor progression and a target for precision therapy

Animal Models and Experimental Medicine, EarlyView.
Overview illustration of dysregulated NFAT activation coordinating upstream signaling, post‐translational regulation and cancer promoting pathways to induce abnormal gene expression that drives tumor development, progression and immune escape. Abstract The Nuclear Factor of Activated T Cells (NFAT) family comprises closely related transcription factors.
Hira Khan, Khushbakhat Alia, Yusra Al Dhaheri, Muhammad Naseem, Rabah Iratni, Edgar Serfling, Khalid Muhammad   +6 more
wiley   +1 more source

Photo‐Triggered, Fast, and Fluorogenic Thiophene‐Based Cycloalkynes for the Bioorthogonal Fluorescent Labeling of 1,3‐Dipole‐Tagged Molecules in No‐Wash Conditions

Angewandte Chemie, EarlyView.
Thiophene is king! The fusion of thiophene rings to cycloalkynes super‐charged their copper‐free click chemistry applications, by (1) enhancing the alkyne reactivity (fastest cyclooctyne to date) and (2) rendering the alkyne fluorogenic (with fluorescence enhancement up to 150‐fold upon reaction), making these bioorthogonal reagents ideal for tracking ...
Jurgen Schulz, Zoeisha S. Chinoy, Tarek Khalaf, Yukang Li, Pengchen Ma, Dennis Svatunek, Kendall N. Houk, Frédéric Friscourt   +7 more
wiley   +1 more source

Neurobiology of Dystonia: Review of Genetics, Animal Models, and Neuroimaging. [PDF]

Brain Sci
Rissardo JP, McGarry A, Shi Y, Caprara ALF, Walker IM.   +4 more
europepmc   +1 more source

Primary writing tremor and writer’s cramp: Distinct phenomenology, diverging pathophysiology

, 2011
Robert Chen, Alberto J. Espay
core   +1 more source

Programmable Solid‐Electrolyte Interfaces for Efficient and Selective Electrochemical Hydrogenations

Angewandte Chemie, EarlyView.
Poly(ionic liquid) binders are shown to actively control the electrode microenvironment, strongly enhancing electrochemical hydrogenation compared to traditional binders. The work redefines the binder as an active component of catalytic electrode design, reshaping local potential gradients and interfacial ion distribution to modulate adsorbed H ...
Anastasios Orestis Grammenos, Jessica Brandt, Yu Zhang, Zeen Wu, Mateusz M. Marzec, Sotirios Sotiropoulos, Piotr Jeleń, Jiayin Yuan, Markus Antonietti, Mateusz Odziomek   +9 more
wiley   +1 more source

Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization

Angewandte Chemie, EarlyView.
The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu, Zeliang Zhang, Benedikt Seligmann, Van Hung Bui, Tuan‐Anh Minh Nguyen, Thu‐Thuy T. Dang, Jakob Franke   +6 more
wiley   +1 more source

Selective Nitrate Transmembrane Transport Through Adaptive Weak C─H Bonding Cyanostilbene Water Channels

Angewandte Chemie, EarlyView.
Here we demonstrate that weak HB CH donor cyanostilbenes promote water/ion transport through their ability to form less‐ordered transient water channels within the lipid bilayer with increased water permeability and NO3−/ Cl− selectivity. ABSTRACT Transmembrane water transport strongly depends on how dynamic, translocating water clusters are stabilized
Ioan Stroia, Dan‐Dan Su, Yuhao Li, Niculina Hadade, Ion Grosu, Arie van der Lee, Mihail Barboiu   +6 more
wiley   +1 more source

Beyond <i>SGCE</i>: expanding the clinical and molecular spectrum of <i>KCTD17</i>- and <i>KCNN2</i>-related myoclonus-dystonia. [PDF]

Front Neurol
Krygier M, Sitek EJ, Chylińska M, Ziętkiewicz S, Zawadzka M, Dulski J, Schinwelski M, Kostrzewa G, Wierzba J, Płoski R, Zech M, Mazurkiewicz-Bełdzińska M.   +11 more
europepmc   +1 more source