Results 91 to 100 of about 136,469 (314)

Teachers’ writing proficiency and assessment ability: the missing link in teachers’ written corrective feedback practice in an Iranian EFL context

open access: yesLanguage Testing in Asia, 2017
Background Teachers’ writing proficiency and writing assessment ability and their role in improving writing instruction in second language learning classrooms are issues that have not been investigated empirically and rigorously.
Majid Nemati   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Writing and reading in Montessori preschools in the digital age – A valid teaching approach?

open access: yesProblemy Wczesnej Edukacji
Writing and reading instruction in Montessori preschools remains consistent despite digital tools. In this article, the validity of Montessori’s reading and writing instruction is reviewed and discussed in relation to both previous research and societal
Per Gynther, Eva-Maria Tebano Ahlquist
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Stylistics in the creative writing curriculum: A problem-posing approach

open access: yes, 2017
The synergies between creative writing instruction and stylistic analysis have been noted for more than a decade in the Stylistics literature – see for example Michael Burke (2010: 7; 2013), Jeremy Scott (2013a; 2013b: 99), et al – but there remain very ...
Bolland, Craig
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Exploring the impacts of academic writing instruction on the use of academic writing norms and conventions: A qualitative study

open access: yesEducational Academic Research
Writing is a far-reaching element which requires the efficient use of linguistic structures and rhetorical patterns for a more advanced writing proficiency.
Canan Aksakallı
doaj   +1 more source

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