Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Growing occupation of professional writing in academic spaces: Combinations of theory and practice
The book chapter, "Growing occupation of professional writing in academic spaces: combinations of theory and practice" is written by the listed authors including Maureen Nicholson (Douglas College).Writing Centres, Writing Seminars, Writing Culture ...
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In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Instructional technology, L2 writing theory, and IFL: a case-study conducted in a British university among tutors and students [PDF]
This study reviews a series of theoretical models and educational experiences, in order to examine how some of the claims made in the existing literature regarding the role of IT - mainly computer technologies - in writing instruction play out in the ...
Mizza, Daria
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Enhancing college English writing through self-efficacy-based instruction
This quasi-experimental study implemented a 15-week instructional intervention targeting first-year non-English major college students. The intervention integrated differentiated instruction, multi-source feedback, and a structured three-phase writing ...
Huiling Jiang
doaj +1 more source
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
The effects of a feedback-based instruction programme on developing EFL writing and revision skills of first year Moroccan university students [PDF]
The stimulus for this study was problems I encountered in my teaching of academic writing to first year undergraduates majoring in English at a Moroccan university. Their problems ranged from sentence, to paragraph to essay levels.
Haoucha, Malika
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Online PBPD and Coaching for Teaching SRSD Argumentative Writing in Middle School Classrooms
Teachers report a need for professional development in order to feel more confident and be more effective in providing writing instruction and intensive intervention to support middle school students.
Amber B. Ray +3 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source

