Results 131 to 140 of about 20,035 (219)

Familiäre Tumorerkrankungen im Knochen [PDF]

, 2018
Zusammenfassung: Familiäre Erkrankungen, die zur Bildung von Knochentumoren führen, sind selten. Sie entwickeln sich im Zusammenhang mit genetischen Alterationen, die den Zellzyklus (Retinoblastomsyndrom/RB1, Li-Fraumeni-Syndrom/p53), wachstumssteuernde ...
Baumhoer, D., Jundt, G.
core  

A stem-cell-derived platform enables complete Cryptosporidium development in vitro and genetic tractability [PDF]

, 2019
Despite being a frequent cause of severe diarrheal disease in infants and an opportunistic infection in immunocompromised patients, Cryptosporidium research has lagged due to a lack of facile experimental methods.
Baldridge, Megan T, Beatty, Wandy L, Funkhouser-Jones, Lisa J, Kuhlenschmidt, Mark S, Kuhlenschmidt, Theresa B, Ravindran, Soumya, Shen, Bang, Sibley, L. David, Stappenbeck, Thaddeus S, VanDussen, Kelli L, Wang, Qiuling, Wang, Yi, Wilke, Georgia, Witola, William H   +13 more
core   +1 more source

Coordination of Nucleases and Helicases during DNA Replication and Double-strand Break Repair [PDF]

, 2009
Nucleases and helicases are involved in numerous steps in DNA replication and repair. Nucleases act on intermediates in DNA replication created by DNA polymerases (Chapter 4) and helicases (Chapter 3).
Budd, Martin E., Cox, Lynne S., Campbell, Judith L.   +2 more
core   +1 more source

Germline variants in patients from the Iranian hereditary colorectal cancer registry

Cancer Cell International
Background and aim Hereditary cancer syndromes account for 6–10% of all colorectal cancer (CRC) cases and 20% of early-onset CRC. Identifying novel pathogenic germline variants can impact genetic testing, counseling, and surveillance. This study aimed to
Lena Goshayeshi, Saeed Hoorang, Benyamin Hoseini, Mohammad Reza Abbaszadegan, Maryam Afrazeh, Maliheh Alimardani, Fatemeh Maghool, Milad Shademan, Morteza Zahedi, Mehrdad Zeinalian, Foroogh Alborzi, Mohammad Reza Keramati, Ashkan Torshizian, Hassan Vosoghinia, Farnood Rajabzadeh, Alireza Bary, Massih Bahar, Ali Javadmanesh, Jamshid Sorouri-Khorashad, Mohammad Hassan Emami, Nasser Ebrahimi Daryani, Hans F.A. Vasen, Ladan Goshayeshi, Hesam Dehghani   +23 more
doaj   +1 more source

Dna2 initiates resection at clean DNA double-strand breaks [PDF]

, 2017
Hunter, Tony, Li, Shan, Paudyal, Sharad C, Yan, Hong, You, Zhongsheng   +4 more
core   +2 more sources

Pathway landscape and regulatory networks of epigenetically modified Breast Cancer genes [PDF]

Epigenetic changes are a key regulator of gene expression in different cancer histotypes. After investigating the differentially expressed genes upon treatment with a demethylating agent, e.g.
Capobianco, Enrico, Cinti, Caterina, El Baroudi, Mariama, La Sala, Dario   +3 more
core  

Ocular Manifestations in Patients with Werner Syndrome. [PDF]

Int J Mol Sci
Oshitari T, Yamaga M, Maezawa Y.
europepmc   +1 more source

Prognostic Significance of DNA Repair Gene mRNA Expression in Early-Stage Breast Cancer: Insights into Clinical Relevance. [PDF]

Oncol Res
Shehaj I, Krajnak S, Almstedt K, Degirmenci Y, Schwab R, Stewen K, Brenner W, Hasenburg A, Schmidt M, Heimes AS.   +9 more
europepmc   +1 more source

Rare genetic diseases associated with G-quadruplex-induced replication stress. [PDF]

Commun Biol
Herr LM, Mukhopadhyay S, Anderson OM, Couch TH, Jones CM, Brosh RM, Rossi M.   +6 more
europepmc   +1 more source

Pan-Cancer Analysis of WRN: From Multi-Omics Biomarker Discovery to Therapy-Guiding Functional Evidence. [PDF]

Onco Targets Ther
Yao QQ, Qi Y, Shi PQ, Yang ZY, Qu P, Zhang WW.   +5 more
europepmc   +1 more source