Results 11 to 20 of about 369 (95)

The occurrence of polyomaviruses WUPyV and KIPyV among patients with severe respiratory infections. [PDF]

Braz J Microbiol, 2019
In 2007, the new polyomaviruses WUPyV and KIPyV were identified in patients with acute respiratory infections. The aim of this study was to investigate these viruses in hospitalized patients with severe acute respiratory infection (SARI). A retrospective study was conducted with 251 patients, from April 2009 to November 2010, using nasopharyngeal ...
Caldeira DB, de Souza Luna LK, Watanabe A, Perosa AH, Granato C, Bellei N.   +5 more
europepmc   +4 more sources

Genetic Diversity of the Noncoding Control Region of the Novel Human Polyomaviruses [PDF]

Viruses, 2020
The genomes of polyomaviruses are characterized by their tripartite organization with an early region, a late region and a noncoding control region (NCCR).
Ugo Moens, Carla Prezioso, Valeria Pietropaolo   +2 more
doaj   +2 more sources

Current and Future Point-of-Care Tests for Emerging and New Respiratory Viruses and Future Perspectives [PDF]

Frontiers in Cellular and Infection Microbiology, 2020
The availability of pathogen-specific treatment options for respiratory tract infections (RTIs) increased the need for rapid diagnostic tests. Besides, retrospective studies, improved lab-based detection methods and the intensified search for new viruses
Philipp P. Nelson, Barbara A. Rath, Barbara A. Rath, Barbara A. Rath, Paraskevi C. Fragkou, Paraskevi C. Fragkou, Emmanouil Antalis, Sotirios Tsiodras, Sotirios Tsiodras, Chrysanthi Skevaki, Chrysanthi Skevaki   +10 more
doaj   +2 more sources

A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin α-dependent nuclear localization signals. [PDF]

Protein Sci
Abstract Nucleocytoplasmic transport regulates the passage of proteins between the nucleus and cytoplasm. In the best characterized pathway, importin (IMP) α bridges cargoes bearing basic, classical nuclear localization signals (cNLSs) to IMPβ1, which mediates transport through the nuclear pore complex.
Cross EM, Akbari N, Ghassabian H, Hoad M, Pavan S, Ariawan D, Donnelly CM, Lavezzo E, Petersen GF, Forwood JK, Alvisi G.   +10 more
europepmc   +2 more sources

DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS. [PDF]

Neuropathology
ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Jauhiainen MK, Mielonen OI, Haapaniemi A, Söderlund-Venermo M, Hagström J, Perdomo MF, Sinkkonen ST, Mäkitie AA.   +7 more
europepmc   +2 more sources

Prevalence of DNA of fourteen human polyomaviruses determined in blood donors. [PDF]

Transfusion, 2019
Abstract BACKGROUND Human polyomaviruses (HPyVs), like herpesviruses, cause persistent infection in a large part of the population. In immunocompromised and elderly patients, PyVs cause severe diseases such as nephropathy (BK polyomavirus [BKPyV]), progressive multifocal leukoencephalopathy (JC polyomavirus [JCPyV]), and skin cancer (Merkel cell ...
Kamminga S, van der Meijden E, de Brouwer C, Feltkamp M, Zaaijer H.   +4 more
europepmc   +2 more sources

Activation of Macrophages by Oligomeric Proteins of Different Size and Origin. [PDF]

Mediators Inflamm, 2018
Activation of macrophages is one of the key processes in generating the immune response against pathogens or misfolded/aggregated otherwise unharmful host’s proteins. Antigens and their immune complexes (IC) may shape macrophage phenotype in various directions.
Dalgėdienė I, Lučiūnaitė A, Žvirblienė A.   +2 more
europepmc   +2 more sources

Infrequent detection of KI, WU and MC polyomaviruses in immunosuppressed individuals with or without progressive multifocal leukoencephalopathy. [PDF]

PLoS ONE, 2011
Conflicting prevalence of newly identified KI (KIPyV), WU (WUPyV) and Merkel Cell Carcinoma (MCPyV) polyomaviruses have been reported in progressive multifocal leukoencephalopathy (PML) patient samples, ranging from 0 to 14.3%. We analyzed the prevalence
Xin Dang, Seweryn Bialasiewicz, Michael D Nissen, Theo P Sloots, Igor J Koralnik, Chen S Tan   +5 more
doaj   +1 more source

WU Polyomavirus in Respiratory Epithelial Cells from Lung Transplant Patient with Job Syndrome

Emerging Infectious Diseases, 2015
We detected WU polyomavirus (WUPyV) in a bronchoalveolar lavage sample from lungs transplanted into a recipient with Job syndrome by using immunoassays specific for the WUPyV viral protein 1.
Erica A. Siebrasse, Diana V. Pastrana, Nang L. Nguyen, Annie Wang, Mark J. Roth, Steven M. Holland, Alexandra F. Freeman, John McDyer, Christopher B. Buck, David Wang   +9 more
doaj   +1 more source

Multiorgan WU Polyomavirus Infection in Bone Marrow Transplant Recipient

Emerging Infectious Diseases, 2016
WU polyomavirus (WUPyV) was detected in a bone marrow transplant recipient with severe acute respiratory distress syndrome who died in 2001. Crystalline lattices of polyomavirus-like particles were observed in the patient’s lung by electron microscopy ...
Erica A. Siebrasse, Nang L. Nguyen, Melisa J. Willby, Dean D. Erdman, Marilyn Menegus, David Wang   +5 more
doaj   +1 more source