The occurrence of polyomaviruses WUPyV and KIPyV among patients with severe respiratory infections. [PDF]
In 2007, the new polyomaviruses WUPyV and KIPyV were identified in patients with acute respiratory infections. The aim of this study was to investigate these viruses in hospitalized patients with severe acute respiratory infection (SARI). A retrospective study was conducted with 251 patients, from April 2009 to November 2010, using nasopharyngeal ...
Caldeira DB +5 more
europepmc +4 more sources
Genetic Diversity of the Noncoding Control Region of the Novel Human Polyomaviruses [PDF]
The genomes of polyomaviruses are characterized by their tripartite organization with an early region, a late region and a noncoding control region (NCCR).
Ugo Moens +2 more
doaj +2 more sources
Current and Future Point-of-Care Tests for Emerging and New Respiratory Viruses and Future Perspectives [PDF]
The availability of pathogen-specific treatment options for respiratory tract infections (RTIs) increased the need for rapid diagnostic tests. Besides, retrospective studies, improved lab-based detection methods and the intensified search for new viruses
Philipp P. Nelson +10 more
doaj +2 more sources
Pathogen Profile of Pediatric Community-Acquired Pneumonia in Wuhan, 2023: A BALF-Based Study. [PDF]
Objective To analyze the distribution characteristics of pathogens in the bronchoalveolar lavage fluid of children with community‐acquired pneumonia. Methods We retrospectively analyzed the etiological data of 1526 children diagnosed and treated at the Maternal and Child Health Hospital of Hubei Province from January 1, 2023, to December 31, 2023 ...
Wang Z +9 more
europepmc +2 more sources
A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin α-dependent nuclear localization signals. [PDF]
Abstract Nucleocytoplasmic transport regulates the passage of proteins between the nucleus and cytoplasm. In the best characterized pathway, importin (IMP) α bridges cargoes bearing basic, classical nuclear localization signals (cNLSs) to IMPβ1, which mediates transport through the nuclear pore complex.
Cross EM +10 more
europepmc +2 more sources
Complete genome analysis of human influenza C virus co-infection with WU polyomavirus in a Sri Lankan child: A brief report [PDF]
Thulani Pattiyakumbura
exaly +2 more sources
DNA Virus Detection in Olfactory Neuroblastomas Using Targeted Enrichment NGS. [PDF]
ABSTRACT A variety of malignancies can be found in the sinonasal tract including the nasal cavity, paranasal sinuses, and skull base. Many of these are attributed to viruses, for example, carcinomas with the presence of transcriptionally active high‐risk human papillomavirus, as well as Epstein–Barr virus associated malignant lymphoepithelial carcinoma
Jauhiainen MK +7 more
europepmc +2 more sources
Prevalence of DNA of fourteen human polyomaviruses determined in blood donors. [PDF]
Abstract BACKGROUND Human polyomaviruses (HPyVs), like herpesviruses, cause persistent infection in a large part of the population. In immunocompromised and elderly patients, PyVs cause severe diseases such as nephropathy (BK polyomavirus [BKPyV]), progressive multifocal leukoencephalopathy (JC polyomavirus [JCPyV]), and skin cancer (Merkel cell ...
Kamminga S +4 more
europepmc +2 more sources
Activation of Macrophages by Oligomeric Proteins of Different Size and Origin. [PDF]
Activation of macrophages is one of the key processes in generating the immune response against pathogens or misfolded/aggregated otherwise unharmful host’s proteins. Antigens and their immune complexes (IC) may shape macrophage phenotype in various directions.
Dalgėdienė I +2 more
europepmc +2 more sources
Infrequent detection of KI, WU and MC polyomaviruses in immunosuppressed individuals with or without progressive multifocal leukoencephalopathy. [PDF]
Conflicting prevalence of newly identified KI (KIPyV), WU (WUPyV) and Merkel Cell Carcinoma (MCPyV) polyomaviruses have been reported in progressive multifocal leukoencephalopathy (PML) patient samples, ranging from 0 to 14.3%. We analyzed the prevalence
Xin Dang +5 more
doaj +1 more source

