Results 91 to 100 of about 5,535 (193)

Light-induced transcriptional responses associated with proteorhodopsin-enhanced growth in a marine flavobacterium [PDF]

, 2011
Proteorhodopsin (PR) is a photoprotein that functions as a light-driven proton pump in diverse marine Bacteria and Archaea. Recent studies have suggested that PR may enhance both growth rate and yield in some flavobacteria when grown under nutrient ...
A Martinez, Asuncion Martinez, BL Taylor, CC Häse, Curtis R Young, Edward F DeLong, EF DeLong, FJ Stewart, FX Cunningham, G Armstrong, G Sabehi, H Futamata, H Tokuda, Hiroyuki Kimura, J McCarren, J McCarren, JD Storey, JL Spudich, JM González, JM Walter, JR de la Torre, K Izui, KC Keiler, L Gómez-Consarnau, LS Brown, M Gomelsky, M Reich, MA Moran, MB Eisen, N-U Frigaard, O Béjà, O Béjà, PP Gardner, PV Attwood, R Gillet, R Lami, S Jitrapakdee, SD Moore, SJ Giovannoni, U Stingl, V Anantharaman, Y Benjamini, Y Shi   +42 more
core   +1 more source

Folate Interaction With Genetic Risk for Neural Tube Defects Among Infants in Bangladesh

Birth Defects Research, Volume 117, Issue 12, December 2025.
ABSTRACT Background Neural tube defects such as spina bifida (SB) are congenital anomalies associated with significant morbidity and mortality worldwide. Environmental factors, particularly folate, modify SB risk. Based on recurrence rates of SB within families, genetic risk also contributes to SB development.
Enrique Mondragon‐Estrada, Xingyan Wang, Michael D. Uhler, Afifah Farooque, Kelly Liu, Sudipta Kumer Mukherjee, Sheikh Muhammad Ekramullah, D. M. Arman, Joynul Islam, Hafiza Sultana Suchanda, David C. Christiani, Benjamin C. Warf, Maitreyi Mazumdar, Sarah U. Morton   +13 more
wiley   +1 more source

Expression of WW domain-containing oxidoreductase WWOX in pterygium.

Molecular vision, 2016
Pterygium was traditionally regarded as a degenerative disease, but certain characteristics suggest that pterygium is probably premalignant tissue. The human WWOX gene, encoding the WW domain containing oxidoreductase (WWOX, FOR, or WOX1), is a candidate tumor suppressor gene.
Yi-Hsun, Huang, Nan-Shan, Chang, Sung-Huei, Tseng   +2 more
openaire   +1 more source

Molecular features of biguanides required for targeting of mitochondrial respiratory complex I and activation of AMP-kinase. [PDF]

, 2016
BACKGROUND: The biguanides are a family of drugs with diverse clinical applications. Metformin, a widely used anti-hyperglycemic biguanide, suppresses mitochondrial respiration by inhibiting respiratory complex I. Phenformin, a related anti-hyperglycemic
Agip, Ahmed-Noor A, Bridges, Hannah R, Hirst, Judy, Sirviö, Ville A   +3 more
core   +1 more source

Negative Immune Regulator CAD7 Functions as a Small‐Molecule Aldehyde Reductase and Increases Histamine Accumulation in Arabidopsis

Molecular Plant Pathology, Volume 26, Issue 12, December 2025.
CAD7 is a reductase with diverse small aldehyde substrates and enhances histamine accumulation and plant susceptibility, while its silencing activates the phenylpropanoid pathway and plant immunity. ABSTRACT Negative immune regulator CAD7 is a non‐canonical member of the CAD (cinnamyl alcohol dehydrogenase) family in plants. However, little is known on
Liwen Ding, Zewen Liu, Weihang Wang, Yang Yang, Ren Sa, Hongmei Wang, Liru Mi, Yalan Qin, Shaocong Kang, Meruyert Medelbek, Assiya Ansabayeva, Yuling Meng, Weixing Shan   +12 more
wiley   +1 more source

Wwox Deletion in Mouse B Cells Leads to Genomic Instability, Neoplastic Transformation, and Monoclonal Gammopathies

Frontiers in Oncology, 2019
WWOX (WW domain containing oxidoreductase) expression loss is common in various cancers and characteristic of poor prognosis. Deletions, translocations, and loss of expression affecting the WWOX gene are a common feature of various B cell neoplasms such ...
Kevin M. McBride, Hyunsuk Kil, Yunxiang Mu, Joshua B. Plummer, Jaeho Lee, Maciej J. Zelazowski, Manu Sebastian, Martin C. Abba, C. Marcelo Aldaz   +8 more
doaj   +1 more source

Real‐Time Detection of Reduced Nitroreductase with a Reversible Fluorescent Probe

Advanced Science, Volume 12, Issue 42, November 13, 2025.
The first reversible binding probe (rNTRp) is presented that selectively detects the nitroreductase enzyme's active, reduced form (red‐NTR) with a fluorescence turn‐on response. Contrary to the conventional reaction‐based probes known to date, which provide only static information on the accumulated enzyme activity at a given time, rNTRp allows ...
Sourav Sarkar, Anushree Shil, Yong Woong Jun, Yun Jae Yang, Ranran Cheng, Wenli Wu, Xuechen Li, Qiongzheng Hu, Kyo Han Ahn   +8 more
wiley   +1 more source

Characterization of three pyranose dehydrogenase isoforms from the litter-decomposing basidiomycete Leucoagaricus meleagris (syn. Agaricus meleagris) [PDF]

, 2016
Nicht verfügbarMultigenicity is commonly found in fungal enzyme systems, with the purpose of functional compensation upon deficiency of one of its members or leading to enzyme isoforms with new functionalities through gene diversification. Three genes of
Graf, Michael M. H., Haltrich, Dietmar, Kittl, Roman, Kracher, Daniel, Ludwig, Roland, Peterbauer, Clemens, Sygmund, Christoph, Weber, Sandra   +7 more
core   +2 more sources

Intermediate Conductance Calcium‐Dependent Potassium Channel (KCa3.1) Interacting Proteins Using Turboid‐Based Proximity Labeling Technology: Insights Into Interactome and Related Signaling Pathways in Pancreatic Tumors

Journal of Cellular Physiology, Volume 240, Issue 9, September 2025.
ABSTRACT KCa3.1 ion channel is a calcium‐activated potassium channel expressed in various tissues, showing dual localization to the plasma membrane and to mitochondria. This channel is highly expressed in numerous cancers and has been implicated in the regulation of proliferation and migration.
Veronica Carpanese, Soha Sadeghi, Luca Matteo Todesca, Ildikò Szabò, Vanessa Checchetto   +4 more
wiley   +1 more source

Wwox deficiency leads to neurodevelopmental and degenerative neuropathies and glycogen synthase kinase 3β-mediated epileptic seizure activity in mice

Acta Neuropathologica Communications, 2020
Human WWOX gene resides in the chromosomal common fragile site FRA16D and encodes a tumor suppressor WW domain-containing oxidoreductase. Loss-of-function mutations in both alleles of WWOX gene lead to autosomal recessive abnormalities in pediatric ...
Ya-Yun Cheng, Ying-Tsen Chou, Feng-Jie Lai, Ming-Shiou Jan, Tsung-Hao Chang, I-Ming Jou, Pei-Shiuan Chen, Jui-Yen Lo, Shiang-Suo Huang, Nan-Shan Chang, Yung-Tsai Liou, Po-Chih Hsu, Hui-Ching Cheng, Yee-Shin Lin, Li-Jin Hsu   +14 more
doaj   +1 more source