Results 131 to 140 of about 169,270 (280)

Peptide–polymer ligands for a tandem WW-domain, an adaptive multivalent protein–protein interaction: lessons on the thermodynamic fitness of flexible ligands

Beilstein Journal of Organic Chemistry, 2015
Three polymers, poly(N-(2-hydroxypropyl)methacrylamide) (pHPMA), hyperbranched polyglycerol (hPG), and dextran were investigated as carriers for multivalent ligands targeting the adaptive tandem WW-domain of formin-binding protein (FBP21).
Katharina Koschek, Vedat Durmaz, Oxana Krylova, Marek Wieczorek, Shilpi Gupta, Martin Richter, Alexander Bujotzek, Christina Fischer, Rainer Haag, Christian Freund, Marcus Weber, Jörg Rademann   +11 more
doaj   +1 more source

Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles. [PDF]

Sci Adv, 2023
Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q.   +7 more
europepmc   +1 more source

Atomic Interlayer Mo–N4 Sites Enable Rapid Charge Transfer and Efficient CO2 Photoreduction

Advanced Science, EarlyView.
This work achieved efficient CO2 activation and ultrafast interlayer electron transport in a 2D COF by constructing atomic‐level Mo‐N4‐induced interlayer electron bridges (IEB), thereby kinetically and thermodynamically co‐driving the photocatalytic coupling of CO2 reduction with 4‐methoxybenzyl alcohol oxidation.
Lijuan Sun, Haiwei Su, Zhen Chen, William Orbell, Guijie Liang, Weikang Wang, Lele Wang, Juan Yang, Qinqin Liu, Junhua Li   +9 more
wiley   +1 more source

Discovery and optimization of a synthetic small protein domain targeting antibodies

Frontiers in Bioengineering and Biotechnology
IntroductionAntibodies and their derivatives constitute a crucial class of molecules in modern biotechnology and therapeutic development. Consequently, identifying chemically robust affinity ligands capable of specifically recognizing antibodies remains ...
Ana Margarida Gonçalves Carvalho Dias, Ana Margarida Gonçalves Carvalho Dias, Manuel João Brandão Matos, Manuel João Brandão Matos, Cátia Soares, Cátia Soares, Carolina Natal, Carolina Natal, Ana Sofia Pina, Ana Sofia Pina, Ana Cecília Afonso Roque, Ana Cecília Afonso Roque   +11 more
doaj   +1 more source

WW domain binding protein 2 (WBP2) as an oncogene in breast cancer: mechanisms and therapeutic prospects-a narrative review. [PDF]

Gland Surg, 2022
Liu Y, He E, Zhang Y, Liu Y, Wang Y, Chen S, Wu X, Zeng Y, Leng P.   +8 more
europepmc   +1 more source

Adhesion‐Driven Removal of Microplastics From Aquatic Systems by Using Microgel Glues

Advanced Science, EarlyView.
Soft polymeric microgels function as “glues” that aggregate diverse microplastics through multivalent adhesion, promoting their interfacial deposition and co‐precipitation for efficient removal from water. Remarkably, this approach remains effective even for nanoscale plastic particles as small as 50 nm.
Jinmeng Zhang, Jie Xu, Wen Chen, Yanping Chen, Zixin Pan, Weitai Wu   +5 more
wiley   +1 more source

Novel Mutation With Literature Review WW Domain-Containing Oxidoreductase (WWOX) Gene. [PDF]

Cureus, 2022
Sukkar G, Alzahrani RM, Altirkistani BA, Al Lohaibi RS.   +3 more
europepmc   +1 more source

Precipitation‐Modulated Harmonic Architectures Enable Superior Strength–Ductility Synergy from Cryogenic to Elevated Temperatures in Nanostructured Alloys

Advanced Science, EarlyView.
Precipitation‐modulated recrystallization enables a programmable bimodal harmonic architecture in a high‐entropy alloy, delivering 1–2 GPa yield strength with >10% ductility from −196 °C to 700 °C. The resulting broad‐temperature robustness arises from the synergy of dual‐mode nanoprecipitation, harmonic core–shell topology, and temperature‐adaptive ...
Wei Li, Liangyin Xiong, Mengchao Niu, Junhua Luan, Wei Wang, Zengbao Jiao   +5 more
wiley   +1 more source

WWP2 promotes the proliferation and metastasis of NSCLC through Hippo pathway and Wnt pathway

Journal of Taibah University for Science
WWP2 (WW domain-containing E3 ubiquitin protein ligase 2), a member of the HECT family of E3 ubiquitin ligases, contains four WW domains and is frequently overexpressed in non-small-cell lung cancer (NSCLC).
Ke Xu, Shu-Yue Wu, Ya-Mei Han, Xiao-Fang Liu, Xu- Yong Lin   +4 more
doaj   +1 more source

Proton TOCSY NMR relaxation rates quantitate protein side chain mobility in the Pin1 WW domain. [PDF]

J Biomol NMR, 2022
Danmaliki GI, Hwang PM.
europepmc   +1 more source