Results 121 to 130 of about 169,270 (280)
Advanced Science, EarlyView.Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi +15 more
wiley +1 more source
Advanced Science, EarlyView.Metal‐free molecular crystal [(CH3C6H10NH3)(18‐crown‐6)][ClO4] functions as a high‐performance molecular ferroelectric. Through strategic methylation of the cyclohexylamine unit, the compound achieves large spontaneous polarization and outstanding piezoelectric coefficients.
Nan Chen +4 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT The lithium plating reaction in graphite electrodes acts as a root cause for the accelerated degradation and the internal short circuits in lithium‐ion batteries. Here, an electrochemical model based on multi‐scale microstructural images was established to identify lithium plating‐stripping processes, thereby supporting the predictive outcomes
Heng Huang +9 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Acute liver injury (ALI), driven by diverse insults such as drug toxicity and ischemia‐reperfusion, poses a high mortality risk and lacks targeted therapies. While reactive oxygen species (ROS), neutrophil extracellular traps (NETs), and a coordinated cell death pathway PANoptosis have been implicated, their interplay as a unified pathogenic ...
Xiaopeng Cai +13 more
wiley +1 more source
MetalCenter‐Dependent Selectivity Divergence in MN4 Single‐Atom Catalysts for Aerobic HMF Oxidation
Advanced Science, EarlyView.Two single‐atom catalysts with M‐N4 configurations (FeN4 and CoN4) were developed for selective HMF oxidation. FeN4 achieves 93.9% selectivity toward FFCA via superoxide anions (O2•−), while CoN4 preferentially produces FDCA through hydroxyl radicals (•OH). DFT calculations reveal that distinct adsorption energies and charge redistribution at the metal
Haoyu Wang +6 more
wiley +1 more source
Engineering gain-of-function mutants of a WW domain by dynamics and structural analysis. [PDF]
Protein Sci, 2023 Lu J +6 more
europepmc +1 more source
Solid‐Like yet Reconfigurable 3D‐Printed Liquid Tubular Wires From Nonconductive Molecules
Advanced Science, EarlyView.This work shatters the current reliance of liquid electronics on intrinsically conductive materials by introducing a novel interfacial redox strategy that transforms non‐conductive molecules into high‐performance, 3D liquid tubular wires with solid‐like electrical properties and exceptional reconfigurability. It opens a vast design space for all‐liquid
Yuchen Fu +6 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Large‐ion (K, Na) battery systems mitigate uneven global lithium distribution, while their ability to attain recharge time shorter than refueling would remove the final barrier for secondary batteries to replace petroleum vehicles. However, their large‐ion chemistry makes ultra‐fast charging an even significant challenge.
Shukai Ding +12 more
wiley +1 more source
The WW domain of IQGAP1 binds directly to the p110α catalytic subunit of PI 3-kinase. [PDF]
Biochem J, 2023 Bardwell AJ +6 more
europepmc +1 more source
Advanced Science, EarlyView.A high‐entropy air electrode material, Gd0.2Pr0.2Ba0.2Sr0.2Ca0.2FeO3−δ (GPBSCF), is developed for both solid oxide fuel cells and reversible protonic ceramic cells. Its enhanced activity stems from increased oxygen vacancies/holes. The stability improvement is attributed to lattice distortion, while thermal expansion reduction is synergistically due to
Ying Zhang +9 more
wiley +1 more source