Results 91 to 100 of about 3,520 (162)

Advancing Flexible Pressure Sensors for Next‐Generation Medical Monitoring

Advanced Sensor Research, Volume 5, Issue 6, June 2026.
This review highlights recent advances in flexible pressure sensors for next‐generation medical monitoring. The sensing mechanisms, material and structural optimization strategies, and intelligent algorithms are systematically summarized. Emerging applications in cardiovascular, respiratory, neurological, laryngeal, and ocular disease monitoring are ...
Chunjun Su, Xingfa Gao, Rixuan Wang, Shuhua Yang, Yinglun Sun   +4 more
wiley   +1 more source

DXS106 and DXS559 flank the X-linked dystonia-parkinsonism syndrome locus (DYT3).

, 1994
The locus (DYT3) underlying the X-linked dystonia-parkinsonism syndrome (XDP) was delineated within proximal Xq12-Xq13.1 by analysis of linkage, allelic association, and haplotypes. Short tandem repeat polymorphisms at loci DXS227, DXS559, DXS453, DXS106,
Fairweather, ND, Müller, U, FAIRWEATHER, N, Wagner, T, Haberhausen, G, Chelly, J, Monaco, Anthony, Fairweather, Nicholas, MONACO, A, Chelly, Jamel, Haberhausen, Gerd, Müller, Ulrich, Wagner, Torsten   +12 more
core   +1 more source

Fibroblast Transcriptomics in Molecular Diagnostics of a Comprehensive Dystonia Cohort

Annals of Neurology, Volume 99, Issue 6, Page 1363-1378, June 2026.
Objective Genomic sequencing leaves >50% of dystonia‐affected individuals without a diagnosis. Where DNA‐oriented approaches remain insufficient, integrating multiomics is essential to advance genome interpretation. Herein, we incorporated RNA sequencing (RNA‐seq) data from 167 patients with dystonia across a range of ages and presentations. Methods We
Alice Saparov, Ivana Dzinovic, Theresa Brunet, Vicente A. Yépez, Florian Hölzlwimmer, Elisabetta Indelicato, Birgit Assmann, Susann Badmann, Diana Ballhausen, Steffen Berweck, Felix Brechtmann, Melanie Brugger, Kevork Derderian, Felix Distelmaier, Philip Harrer, Denisa Harvanova, Petra Havrankova, Ann‐Kathrin Jaroszynski, Miriam Kolnikova, Robert Kopajtich, Anne Koy, Magdalena Krygier, Lukas Kunc, Katarina Kusikova, Oliver Maier, Maria Mazurkiewicz‐Bełdzińska, Christian Mertes, Ava Oberlack, Timo Roser, Alexandra Sitzberger, Ugo Sorrentino, Antonia M. Stehr, Katharina Vill, Matias Wagner, Holger Prokisch, Sylvia Boesch, Jan Necpal, Robert Jech, Juliane Winkelmann, Elisabeth Graf, Julien Gagneur, Matej Skorvanek, Michael Zech   +42 more
wiley   +1 more source

Reduced Neuron-Specific Expression of the TAF1 Gene Is Associated with X-Linked Dystonia-Parkinsonism

, 2007
X-linked dystonia-parkinsonism (XDP) is a movement disorder endemic to the Philippines. The disease locus, DYT3, has been mapped to Xq13.1. In a search for the causative gene, we performed genomic sequencing analysis, followed by expression analysis of ...
Tabuena, Ma. Daisy, Tomizawa, Maiko, Matsumoto, Shinnichi, Tooyama, Ikuo, Kaji, Ryuji, Ando, Satoshi, Maranon, Elma, Makino, Satoshi, Dantes, Marita, Ogasawara, Kazumasa, Goto, Satoshi, Lee, Lillian V., Nishimura, Masataka, Tamiya, Gen, Yasuno, Katsuhito, Akatsu, Hiroyasu   +15 more
core   +1 more source

Beyond the Homunculus—SCAN‐AMN as a Shared Action‐Oriented Neural Substrate across Movement Disorders

Movement Disorders, EarlyView.
Arjun Balachandar, Alvaro Hernandez‐Guillen, Nico U.F. Dosenbach, Anthony E. Lang, Christos Ganos   +4 more
wiley   +1 more source

Long-Term Outcomes of Bilateral Pallidal Deep Brain Stimulation for X-Linked Dystonia and Parkinsonism.

, 2018
BACKGROUND: X-linked dystonia parkinsonism (XDP) causes adult-onset progressive dystonia and parkinsonism, which may not respond to pharmacotherapy. OBJECTIVE: Previous case reports have reported beneficial effects from bilateral pallidal (GPi) deep ...
Witt, Jennifer, Glass, Graham A, Heath, Susan, Galifianakis, Nicholas B, Starr, Philip A, Volz, Monica, Ostrem, Jill Louise, Kilbane, Camilla   +7 more
core  

Insights into molecular mechanisms of disease in Neurodegeneration with Brain Iron Accumulation; unifying theories.

, 2016
Neurodegeneration with brain iron accumulation (NBIA) is a group of disorders characterised by dystonia, parkinsonism and spasticity. Iron accumulates in the basal ganglia and may be accompanied by Lewy bodies, axonal swellings and hyperphosphorylated ...
Arber, C, Houlden, H, H. Houlden, C. E. Arber, S. Wray, Wray, S, A. Li, Li, A   +7 more
core   +1 more source

The roles of TAF1 in neuroscience and beyond

Royal Society Open Science
The transcriptional machinery is essential for gene expression and regulation; dysregulation of transcription can result in a range of pathologies, including neurodegeneration, cancer, developmental disorders and cardiovascular disease.
Elisa M. Crombie, Karen Cleverley, H. T. Marc Timmers, Elizabeth M. C. Fisher   +3 more
doaj   +1 more source

Disease onset in X-linked dystonia-parkinsonism correlates with expansion of a hexameric repeat within an SVA retrotransposon in TAF1

, 2017
Significance The genetic basis of X-Linked dystonia-parkinsonism (XDP) has been difficult to unravel, in part because all patients inherit the same haplotype of seven sequence variants, none of which has ever been identified in ...
Rachita Yadav, Mai-Linh Ton, Christine A. Vaine, Xandra O. Breakefield, Jyotsna Dhakal, Naoto Ito, Kotchaphorn Mangkalaphiban, Christopher T. Russo, William T. Hendriks, Nutan Sharma, D. Cristopher Bragg, Patrick Acuña, Ulrich Müller, David Shin, Trisha Multhaupt-Buell, Nichita J. Kulkarni, Criscely Go, Mark Ang, Laurie J. Ozelius, Anne Cheng, Taylor N. Francoeur   +20 more
core   +1 more source

Research productivity of the Department of Neurosciences of the University of the Philippines Manila: a bibliometric analysis

Cogent Education
Research output is widely recognized as a key indicator of productivity and a measure of the status of a nation’s research activity. This bibliometric analysis examined the research productivity of the Department of Neurosciences at the University of the
Mykha Marie B. Tabuzo, Ena Elizabeth L. Naoe, Veeda Michelle M. Anlacan, Roland Dominic G. Jamora   +3 more
doaj   +1 more source