Results 131 to 140 of about 107,799 (290)

XANTHINE OXIDASE

Journal of Biological Chemistry, 1957
Irwin Fridovich, Philip Handler
openaire   +1 more source

Anthocyanin Identification of Methanol-HCl Extract Active Fraction in Rosella (Hibiscus Sabdariffa. L) and Its Potential as Xanthine Oxidase Inhibitor [PDF]

, 2014
The active fraction of methanol-HCl extract of Roselle flower (Hibiscus sabdariffa. L) has been identified and its inhibitor xanthine oxidase potential tested. The aim of this study was to compare the inhibitory activity of xanthine oxidase from methanol-
Anam, K. (Khairul), Kusrini, D. (Dewi), Lestari, P. P. (Pratiwi)   +2 more
core  

Calciprotein particle‐induced calcium overload triggers mitochondrial dysfunction in endothelial cells

The Journal of Physiology, EarlyView.
Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra, Laurent Chatre, Benoit Bernay, Julien Pontin, Mirjam F. Mastik, Azuwerus van Buiten, Dalibor Nakládal, Bastiaan S. Star, Jan‐Luuk Hillebrands, Guido Krenning   +9 more
wiley   +1 more source

Research and development of non-enzymatic electrochemical sensors utilizing porous ZnO/graphene electrodes to determine xanthine

Tạp chí Kiểm nghiệm và An toàn thực phẩm
In this study, we developed a non-enzymatic electrochemical sensor using a porous graphene electrode modified with ZnO nanoparticles (ZnO/fPGE sensor) to determine xanthine (XA) content.
Ta Ngoc Bach, Nguyen Xuan Viet, Nguyen Van Anh, Pham Quang Trung, Nguyen Thi Minh Thu, Phung Thi Thu, Vu Hong Ky, Do Hung Manh, Vu Dinh Lam, Nguyen Huy Dan, Trinh Xuan Anh, Ngo Thi Hong Le   +11 more
doaj   +1 more source

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source

Efficient Detection of Xanthine Content in Edible Mushrooms Using Electrochemical Sensors Based on g-C3N4

Shipin gongye ke-ji
This study aimed to construct a highly sensitive, reliable, and low-cost electrochemical sensor based on graphitic carbon nitride (g-C3N4) modified materials for efficient and convenient detection of purine content in edible mushrooms.
Zhiyan CHEN, Zuyun ZHAO, Yixin CHEN, Yixuan REN, Yajun GAO   +4 more
doaj   +1 more source

Model‐Based Strategy for 6‐Mercaptopurine Treatment in Acute Lymphoblastic Leukemia Maintenance Phase: Prediction of 6‐TGN and 6‐MMP Concentrations to Optimize Treatment

Pediatric Blood &Cancer, Volume 73, Issue 4, April 2026.
ABSTRACT Introduction Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. The pro‐drug 6‐mercaptopurine (6‐MP), essential during maintenance, is converted into active 6‐thioguanine (6‐TGN) and toxic 6‐methylmercaptopurine (6‐MMP) metabolites, resulting in marked variability in efficacy and toxicity.
Anne Ravix, Anaïs Maillat, Eva Choong, Chantal Csajka, Monia Guidi, Francesco Ceppi   +5 more
wiley   +1 more source

Potential Hypoglycemic, Hypolipidemic, and Hypouricemic Bioactive Components From Ampelopsis grossedentata Explored by Affinity Ultrafiltration With Three Enzyme Targets

eFood, Volume 7, Issue 2, April 2026.
By integrating bioaffinity ultrafiltration coupled with HPLC‐MS/MS, this study identified quercetin, myricetrin, dihydromyricetin, and taxifolin from Ampelopsis grossedentata as key inhibitors of α‐glucosidase, pancreatic lipase, and xanthine oxidase, highlighting the promising potential of A.
Siyang Mao, Chu Chu, Yanzhi Xiong, Mengjia Xu, Jian Yang, Mingquan Guo   +5 more
wiley   +1 more source

Potential to Improve Nitrogen Fertilizer Use Efficiency and Mitigate Pollution in Tropical Pastures Grazed by Sheep

New Zealand Journal of Agricultural Research, Volume 69, Issue 2, April 2026.
We hypothesize that increasing N application rates will affect N use efficiency (NUE) for lambs grazing warm‐season annual grasses. We evaluated the effect of N fertilizer application rates (50, 100, 200, and 400 kg N/ha) on forage pearl millet (Pennisetum glaucum (L.) R.) and animal responses: N balance and NUE per animal and per area basis.
Diego Bitencourt de David, Cesar Henrique Espírito Candal Poli, Eduardo Bohrer de Azevedo, Jean Víctor Savian, Marta Moura Kohmann, Paulo César de Faccio Carvalho   +5 more
wiley   +1 more source

Differential Analysis of IAA Anabolism Pathway Based on Bacillus cereus, Bacillus subtilis and Bacillus safensis Genome

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Three Bacillus species isolated from Platycladus orientalis rhizosphere in Taihang Mountains: Bacillus cereus has 3 IAA synthesis pathways (TAM, IAM, IPyA); Bacillus subtilis has IAM/IPyA; and Bacillus safensis only has IPyA (via whole‐genome sequencing).
Dongyue Hou, Xuejie Zhai, Kezhong Zhang, Jinteng Cui   +3 more
wiley   +1 more source