Results 131 to 140 of about 89,320 (324)
The chemistry of xanthine oxidase. 5. Electron-spin resonance of xanthine oxidase solutions [PDF]
, 1959 Robert C. Bray +2 more
openalex +1 more source
A Xanthine Derivative With Novel Heat Shock Protein 90‐Alpha Inhibitory and Senolytic Properties
Aging Cell, EarlyView.This study aimed to find safe senolytic drugs that selectively eliminate senescent cells. Focusing on HSP90 inhibitors, we employed a virtual screening to identify novel, safer compounds (A). K5, a xanthinic candidate, effectively eliminated senescent cells in various cellular models (B), extended lifespan in flies, and reduced aging signs in mice (C).
Sandra Atlante +24 more
wiley +1 more source
Studies on xanthine oxidase [PDF]
Biochemical Journal, 1934 David Ezra Green, Malcolm Dixon
openaire +3 more sources
Further Studies with Xanthine Oxidase Inhibitors
, 1959 W.W. Westerfeld +2 more
openalex +1 more source
Brain Pathology, Volume 35, Issue 3, May 2025.Aerobic exercise improves transfer of healthy mitochondria from astrocytes to neurons in the 5 × FAD mice. Abstract Mitochondrial dysfunction is a well‐established hallmark of Alzheimer's disease (AD). Despite recent documentation of transcellular mitochondrial transfer, its role in the pathogenesis of AD remains unclear.
Jiachen Cai +10 more
wiley +1 more source
Steps in the oxidation of xanthine to uric acid catalysed by milk xanthine oxidase [PDF]
, 1959 H. Gutfreund, Julian M. Sturtevant
openalex +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and purpose Thiopurines are used in paediatric inflammatory bowel disease (IBD), but some patients do not respond. Because the gut microbiota influences drug efficacy and IBD‐patient microbiota presents increased bacterial abundance, we investigated the impact of candidate Enterobacteriaceae on drug cytotoxicity, metabolism and ...
Martina Franzin +13 more
wiley +1 more source
KHẢO SÁT KHẢ NĂNG ỨC CHẾ ENZYME XANTHINE OXIDASE TỪ LÁ SA KÊ (ARTOCARPUS ALTILIS (PARK.) FOSB)
Tạp chí Khoa học Đại học Cần Thơ, 2014 Tăng acid uric không chỉ là nguyên nhân gây nên bệnh gout, mà còn làm tăng nguy cơ bệnh tim mạch, sỏi thận, đái tháo đường và các hội chứng chuyển hóa.
Đái Thị Xuân Trang +2 more
doaj
NOTES ON THE QUANTITATIVE DETERMINATION OF XANTHINES AND URIC ACIDS IN PLASMA
, 1958 Felix Bergmann +2 more
openalex +1 more source
Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals
Cell Proliferation, EarlyView.One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye +6 more
wiley +1 more source