Results 131 to 140 of about 147,306 (350)

Novel electrochemical xanthine biosensor based on chitosan–polypyrrole–gold nanoparticles hybrid bio-nanocomposite platform [PDF]

, 2017
Muamer Dervisevic, Esma Dervisevic, Emre Çevik, Mehmet Şenel   +3 more
openalex   +1 more source

Identification of Candidate Blood Biomarkers of Recombinant Human Erythropoietin Administration Using Targeted Polar Metabolomics by HILIC‐MS/MS

Drug Testing and Analysis, EarlyView.
Using targeted HILIC‐MS/MS metabolomics, inosine and hypoxanthine were identified as potential biomarkers of EPO administration. Their consistent and sensitive plasma responses highlight their promise for inclusion in the Athlete Biological Passport (ABP), warranting further investigation to enhance anti‐doping detection strategies. ABSTRACT Increasing
Olivier Salamin, Lejla Ramic, Raul Nicoli, Serge Rudaz, Davy Guillarme, Tiia Kuuranne   +5 more
wiley   +1 more source

Quantification of Uric Acid or Xanthine in Plant Samples

Bio-Protocol, 2015
We developed this protocol to assay and quantify the content of uric acid or xanthine in various tissues of Arabidopsis thaliana mutant lines with defective urate oxidase or xanthine dehydrogenase1 and in their complementation and suppressor lines (Hauck
Oliver Hauck, Claus-Peter Witte
doaj   +1 more source

Correction to the “Posters” for “bridging continents to advance life science 49th FEBS congress, 5–9 July 2025, Istanbul, Türkiye”

FEBS Open Bio, EarlyView.
wiley   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Xanthine Phosphoribosyltransferase from Leishmania donovani [PDF]

, 1999
Armando Jardim, Susan E. Bergeson, Sarah Shih, Nicola Carter, Randall W. Lucas, Gilles Merlin, Peter J. Myler, Kenneth Stuart, Buddy Ullman   +8 more
openalex   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Participation of reactive oxygen species in regulation of Са2+ - activated К + channels of erythrocytes

Бюллетень сибирской медицины, 2009
In this study, we investigated the effects of preincubation with the reactive oxygen species-generating system xanthine oxidase/xanthine on Ca2+-dependent potassium permeability of erythrocyte membrane. The increase of intracellular calcium concentration
O. A. Trubacheva, S. V. Kremeno, I. V. Petrova, A. V. Sitozhevsky, O. V. Gruzdeva, V. V. Ivanov, T. Ye. Suslova   +6 more
doaj   +1 more source

A Comprehensive Review of Probiotics in Alleviating Hyperuricemia: Mechanisms, Strain Engineering, and Food Applications

Food Bioengineering, EarlyView.
Screening and modification of probiotics that can efficiently reduce uric acid provide a new strategy for food‐grade hyperuricemia intervention. ABSTRACT Hyperuricemia has become one of the most prevalent global epidemics, significantly impacting both the economy and the health of individuals.
Le Wang, Qi Wu, Mengjia Zhang, Zifu Ni, Pengshuai Zhang, Siyuan Bai, Yibin Wang, Zhongke Sun   +7 more
wiley   +1 more source

Oxidative stress in the pathogenesis of type 1 diabetes: the role of adipocyte xanthine oxidase

Бюллетень сибирской медицины, 2018
Rationale. According to modern understanding, oxidative stress plays an essential role in the underlying mechanisms for the emergence of type 1 and type 2 diabetes and development of complications in these conditions.
V. V. Ivanov, E. V. Shakhristova, E. A. Stepovaya, N. V. Litvjakov, N. A. Perekucha, O. L. Nosareva, T. S. Fedorova, V. V. Novitsky   +7 more
doaj   +1 more source